Eugenia uniflora L.: potential uses as a bioactive plant

Moura, Gabriela Silva; Oliveira, Ivan Júnior de; Bonome, Lisandro Tomas da Silva; Franzener, Gilmar

doi:10.1590/1808-1657000752017

Cited by 9 publications

(5 citation statements)

References 44 publications

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“…However, by using a solid-phase extraction technique, this is the first study to identify and quantify quercetin by HPLC, which contributes to quality control studies of plant extracts. The βsitosterol isolated from DEE was previously described by Samy et al [32], in the EtOAc fraction obtained from the methanolic extract of E. uniflora leaves. The flavonoids and steroids found in E. uniflora have been documented as natural bioactive products with potent anticancer activity [33,34].…”

Section: Discussionmentioning

confidence: 99%

Chemical Analysis and in Vitro Antiproliferative Potential of Eugenia uniflora L. (Myrtaceae)

Gomes

Zanchet

Serpa

et al. 2020

EJMP

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Natural products and especially medicinal plants, have been extensively studied and have exhibited antiproliferative effects. The species Eugenia uniflora L. (Myrtaceae) is native to Brazil and distributed throughout Australia, East Asia, and the Americas. The leaves are commonly used for the treatment of diarrhea, fever, and hypertension. However, the chemical properties and antiproliferative potential of the extracts remain to be elucidated. In this work, the antiproliferative effects of hydroethanolic (HEE) and dichloromethane (DEE) extracts of leaves from E. uniflora against a panel of human tumor cell lines in vitro were evaluated. Quercetin was identified using an HPLC, and the chemical component β-sitosterol was isolated. The HEE was an inactive extract, whereas the DEE extract showed antiproliferative activity against OVCAR-3 ovarian cells. In a bioassay-guided process, more pronounced antiproliferative effects were found for β-sitosterol isolated from DEE, which demonstrated potent antiproliferative effects against glioblastoma (U-251 cells) and leukemia (K-562 cells). This study contributes to the knowledge of E. uniflora and suggests that β-sitosterol is a potential chemotherapeutic compound.

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Section: Discussionmentioning

confidence: 99%

Chemical Analysis and in Vitro Antiproliferative Potential of Eugenia uniflora L. (Myrtaceae)

Gomes

Zanchet

Serpa

et al. 2020

EJMP

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“…Dentre os métodos existentes para calcular as interações entre substâncias ativas, utilizou-se o Índice Segundo Moura et al (2018) vários estudos demonstram a presença de antraquinonas, esteroides, triterpenos, heterosídeos de flavonoides, de saponina e de taninos, sesquiterpenos, compostos fenólicos, antocianinas, flavonoides e carotenoides nas folhas de E. uniflora, sugerindo assim, um importante potencial fitoterápico a ser investigado.…”

Section: Determinação Do íNdice Da Concentração Inibitória Fracionári...unclassified

TESTE DE SINERGISMO DA ATIVIDADE ANTIMICROBIANA DOS EXTRATOS DE Eugenia uniflora E PRÓPOLIS POR MÉTODO DE CHECKERBOARD

Dalmagro

Donadel

Pinc

et al. 2022

REMS

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Introdução: A crescente resistência bacteriana aos antibióticos tornou-se uma ameaça à população. Devido ao avanço da fitoterapia nos últimos anos, estudos sobre a ação antimicrobiana de diferentes bioativos têm sido incentivados cada vez mais. De acordo com a literatura, Eugenia uniflora apresenta composição química complexa e seus compostos possuem atividade terapêutica anti-inflamatória, hipotensora, hipoglicemiante, antipirética e antibacteriana. No própolis, foram identificados cerca de 300 compostos relacionados a atividades farmacológicas como anti-inflamatória, antioxidante, antifúngica, hepatoprotetora e antibacteriana. Objetivo: Portanto, o trabalho teve como objetivo avaliar a atividade antimicrobiana individual e combinada dos extratos de E. uniflora e Própolis por checkerboard. Metodologia: Os extratos foram testados em triplicata, frente a Candida albicans, Escherichia coli e Staphylococcus aureus. A incubação foi realizada por 24 horas a 35 ± 2 ºC para bactérias, e 48 horas a 25 ± 2 ºC para o fungo. A avaliação dos resultados bacterianos foi realizada empregando cloreto de trifeniltetrazólio a 2% e a multiplicação fúngica pela turvação do meio. Resultados: Foram encontrados os valores de 62,50 e 7,81 mg/mL para C. albicans, E. coli 7,81 e 3,90 mg/ mL e S. aureus 7,81 e 7,81 mg/mL, para própolis e E. uniflora, respectivamente, quando combinados. Ao calcular o índice de concentração inibitória fracional, observou-se que os valores se compreenderam entre 0,74 e 1,06, indicando que não ocorreu interação entre os extratos avaliados. Conclusão: Assim, apesar da atividade antimicrobiana já comprovada para os extratos de E. uniflora e própolis, a combinação dos extratos não apresentou efeito sinérgico nas condições e metodologia avaliada.

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“…In traditional medicine, pitanga leaves are used as antipyretic, antidiarrheal, antihypertensive, 4,5 antimicrobial 6 as well as in the treatment of sore throat, rheumatism, and headaches 5 . E. uniflora can also be used in the heterogeneous reforestation since it is a light‐demanding pioneer and a salt tolerance species 7 …”

Section: Introductionmentioning

confidence: 99%

In vitro germination and controlled release fertilizer effects on ex vitro development of Eugenia uniflora L. plantlets

2022

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Background Eugenia uniflora L (Myrtaceae) is a native shrub from Brazil and is used in traditional medicine and also in the food industry to produce different types of juices, jellies, ice cream, and can also be consumed unprocessed. This species is propagated by seeds, which have irregular germination leading to low producer orchards affecting its economic viability for large‐scale production and the quality of seedlings. Thus, the main goal of this study was to evaluate different in vitro germination conditions and the effects of substrate and fertilizer on ex vitro plantlets development. Results Seeds germinated in MS0 under light had the highest speed germination index (1.63). The highest root system length was observed in seeds cultivated in MS + 1 μmol GA3 in the presence of light (12.85 cm). Plantlets developed under MS + 1 μmol GA3 in the presence of light, showed the highest dry weight mass (29.7 mg). The three‐way ANOVA indicated that the type of fertilizer, culture medium, and light conditions separately showed significant effects on shoot length (p < 0.0001, 0.0278, and 0.036 respectively), root collar diameter (p < 0.0001, 0.0428, and 0.0165, respectively) and also for the fresh and dry weight of the shoot, just by the type of fertilizer (p < 0.0001) and culture medium (p < 0.05) used. Conclusion It was concluded that MS0 under light is the most suitable condition for Brazilian cherry germination and commercial substrate plus the controlled release NPK 15‐9‐12 fertilizer provides better plant growth.

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Eugenia uniflora L.: potential uses as a bioactive plant

Cited by 9 publications

References 44 publications

Chemical Analysis and in Vitro Antiproliferative Potential of Eugenia uniflora L. (Myrtaceae)

Chemical Analysis and in Vitro Antiproliferative Potential of Eugenia uniflora L. (Myrtaceae)

TESTE DE SINERGISMO DA ATIVIDADE ANTIMICROBIANA DOS EXTRATOS DE Eugenia uniflora E PRÓPOLIS POR MÉTODO DE CHECKERBOARD

In vitro germination and controlled release fertilizer effects on ex vitro development of Eugenia uniflora L. plantlets

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