Evaluation of an antibacterial orthodontic adhesive incorporated with niobium-based bioglass: an in situ study

Degrazia, Felipe Weidenbach; Altmann, Aline Segatto Pires; Ferreira, Carolina Jung; Arthur, Rodrigo Alex; Leitune, Vicente Castelo Branco; Samuel, Susana Maria Werner; Collares, Fabrício Mezzomo

doi:10.1590/1807-3107bor-2019.vol33.0010

Cited by 19 publications

(8 citation statements)

References 42 publications

(57 reference statements)

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“…Altmann et al [ 85 ] developed an orthodontic adhesive containing 1,3,5-triacryloylhexahydro-1,3,5-triazine with antibacterial activity ( S. mutans ). Degrazia et al [ 88 ] used the orthodontic adhesive containing triazine and niobium phosphate bioglass around brackets. This approach resulted in the inhibition of S. mutans and total Streptococci increase and, additionally, an anti-demineralization effect.…”

Section: Resultsmentioning

confidence: 99%

Functional Coatings for Orthodontic Archwires—A Review

et al. 2020

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In this literature review, the current state-of-art of coatings for orthodontic archwires’ increasing antimicrobial and relevant mechanical properties, such as surface topography, friction or corrosion resistance, has been presented. There is a growing request for orthodontic appliances, therefore, most researchers focus on innovative functional coatings to cover orthodontic archwires and brackets. Orthodontic appliances are exposed to the unfavorable oral cavity environment, consisting of saliva flow, food, temperature and appliance force. As a consequence, friction or biocorrosion processes may occur. This can affect the functionality of the orthodontic elements, causing changes in their microstructure, surface topography and mechanical properties. Furthermore, the material which the orthodontic archwire is made from is of particular importance in terms of the possible corrosion resistance. This is especially important for patients who are hypersensitive to metals, for example, nickel, which causes allergic reactions. In the literature, there are some studies, carried out in vitro and in vivo, mostly examining the antibacterial, antiadherent, mechanical and roughness properties of functional coatings. They are clinically acceptable but still some properties have to be studied and be developed for better results. In this paper the influence of additives such as nanoparticles of silver and nitrogen-doped TiO2 applied on orthodontic brackets by different methods on the antimicrobial properties was analyzed. Future improvement of coating techniques as well as modification of the archwire composition can reduce the release of nickel ions and eliminate friction and bacterial adhesion problems, thus accelerating treatment time.

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Section: Resultsmentioning

confidence: 99%

Functional Coatings for Orthodontic Archwires—A Review

et al. 2020

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“…The study’s findings demonstrate that there was no discernible difference between the antibacterial monomer-containing primer group and the control group in terms of their capacity to prevent demineralization during orthodontic treatment [ 68 ]. Degrazia et al, examined the demineralization and antibacterial properties of an experimental orthodontic adhesive made of triazine and niobium bioglass phosphate (TAT) around attachments placed on enamel surfaces [ 31 ]. From the results of this study, the growing of S. mutans and total streptococcus were inhibited by the adhesive in the triazine and niobium phosphate-based bioglass, which had an anti-demineralization impact.…”

Section: Discussionmentioning

confidence: 99%

White Spots: Prevention in Orthodontics—Systematic Review of the Literature

Patano

Malcangi

Sardano

et al. 2023

IJERPH

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Early-stage dental demineralization, called white spots (WS), get their name from the characteristic colour that enamel takes on due to the acid attack of salivary cariogenic bacteria. They are often associated with fixed orthodontic therapy (FOT) and, if left untreated, evolve into caries with repercussions on oral health and dental aesthetics. This review aims to identify the most effective prophylaxis strategies to prevent WS during FOT. The search for the reviewed studies was conducted on the Pubmed, Scopus, and Web of Science databases, selecting English-only articles published in the 5 years from January 2018 to January 2023. The keywords used were “WS” and “fixed orthodontic*”, using “AND” as the Boolean operator. A total of 16 studies were included for qualitative analysis. Prevention begins with maintaining proper oral hygiene; fluoride in toothpaste, mouthwashes, gels, varnishes, and sealants can be added to prophylaxis and used regularly. Using a laser in combination with fluoride helps prevent the occurrence of WS and assists in the repair processes of initial lesions. Further studies are needed to establish international guidelines for preventing WS in orthodontically treated patients.

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“…Future studies are encouraged to investigate the antibacterial activity of dental materials with MC-IL and analyze if the SFE and contact angle differences could interfere with the antibacterial property. Furthermore, in situ studies [ 47 ] applying the infiltrants in enamel is an exciting future study to translate the knowledge from the bench to the clinical setting.…”

Section: Discussionmentioning

confidence: 99%

Ionic liquid-loaded microcapsules doped into dental resin infiltrants

Cuppini

García

Souza

et al. 2021

Bioactive Materials

Self Cite

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Resin infiltrants have been effectively applied in dentistry to manage non-cavitated carious lesions in proximal dental surfaces. However, the common formulations are composed of inert methacrylate monomers. In this study, we developed a novel resin infiltrant with microcapsules loaded with an ionic liquid (MC-IL), and analyzed the physical properties and cytotoxicity of the dental resin. First, the ionic liquid 1- n -butyl-3-methylimidazolium bis(trifluoromethanesulfonyl)imide (BMI.NTf 2 ) was synthesized. BMI.NTf 2 has previously shown antibacterial activity in a dental resin. Then, MC-IL were synthesized by the deposition of a preformed polymer. The MC-IL were analyzed for particle size and de-agglomeration effect via laser diffraction analysis and shape via scanning electron microscopy (SEM). The infiltrants were formulated, and the MC-IL were incorporated at 2.5%, 5%, and 10 wt%. A group without MC-IL was used as a control. The infiltrants were evaluated for ultimate tensile strength (UTS), contact angle, surface free energy (SFE), and cytotoxicity. The MC-IL showed a mean particle size of 1.64 (±0.08) μm, shriveled aspect, and a de-agglomeration profile suggestive of nanoparticles' presence in the synthesized powder. There were no differences in UTS among groups (p > 0.05). The incorporation of 10 wt% of MC-IL increased the contact angle (p < 0.05), while the addition from 5 wt% reduced the SFE in comparison to the control group (p < 0.05). The human cell viability was above 90% for all groups (p > 0.05). The incorporation of microcapsules as a drug-delivery system for ionic liquids may be a promising strategy to improve dental restorative materials.

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Evaluation of an antibacterial orthodontic adhesive incorporated with niobium-based bioglass: an in situ study

Cited by 19 publications

References 42 publications

Functional Coatings for Orthodontic Archwires—A Review

Functional Coatings for Orthodontic Archwires—A Review

White Spots: Prevention in Orthodontics—Systematic Review of the Literature

Ionic liquid-loaded microcapsules doped into dental resin infiltrants

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