Antimicrobial activity of different disinfectants against cariogenic microorganisms

Çelik, Esra Uzer; Tunaç, Ayşe Tuğçe; Ateş, Mustafa; Şen, Bilge Hakan

doi:10.1590/1807-3107bor-2016.vol30.0125

Cited by 23 publications

(10 citation statements)

References 37 publications

(39 reference statements)

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“…From the present finding, it is revealed of S. mutans ATCC 25175 in vitro at levels as low as 6.24 mg/ml. We used chlorhexidine as a positive control in the study, because it is still commercially used as one of the treatment options for S. mutans (Eden, 2008) and interestingly, the MIC value for AVCO is found to be lower than the MIC value for chlorhexidine from previous study (Uzer Celik et al, 2016). The excellent A similar finding after hydrolysing VCO with lipolytic Geotrichum candidum was observed by Khoramnia et al (2013), suggesting that the enzymatic reaction had improved the medium-chain fatty acids contents in VCO and its antimicrobial activity.…”

Section: Minimum Inhibitory Concentration (Mic) Of Avco and Vcomentioning

confidence: 97%

Fatty Acid Evaluation and Antimicrobial Activity of Virgin Coconut Oil and Activated Virgin Coconut Oil on Streptococcus mutans

Haron¹,

Mukhtar²,

Omar³

et al. 2019

AOS

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For decades, coconut oil was reported to possess a broad spectrum of antimicrobial activity due to its abundant fatty acid's contents. Streptococcus mutans (S. mutans) has been strongly implicated as the main etiological factor in dental caries. Regardless of the ongoing medical advances, the therapeutic resources for dental caries remain ineffectual, and this has led to renewed interest in using virgin coconut oil (VCO) as a possible choice for dental caries control. In this study, the ability of VCO and activated virgin coconut oil (AVCO) combatting cariogenic S. mutans ATCC 25175 has been evaluated. Fatty acids contents were compared through gas chromatography-mass spectrum (GC-MS) analysis, and their antimicrobial activity was determined using disc diffusion and minimum inhibitory concentration (MIC) test. From the GC-MS analysis, AVCO (59%) was found to have a slightly higher medium-chain fatty acids (MCFA) as compared to VCO (54.1%), and the long-chain fatty acids (LCFA) contents in VCO (45.9%) was found to be higher than AVCO (41%). Interestingly, S. mutans ATCC 25175 was found to be susceptible towards AVCO (MIC: 6.24 mg/ml) and resistance towards VCO in vitro. The excellent antimicrobial activity of AVCO as a result from (i) the release of individuals fatty acids after activation of VCO by lipase digestion and (ii) the present of MCFA and LCFA that are significant in antimicrobial activity. Further study can be designed to specifically examine the activity of individuals fatty acids present in oils against S.mutans virulence genes/protein using molecular dynamic assessment.

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Section: Minimum Inhibitory Concentration (Mic) Of Avco and Vcomentioning

confidence: 97%

Fatty Acid Evaluation and Antimicrobial Activity of Virgin Coconut Oil and Activated Virgin Coconut Oil on Streptococcus mutans

Haron¹,

Mukhtar²,

Omar³

et al. 2019

AOS

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“…Octenidine dihydrochloride (OCT; Octenisept ® , schülke ™ , Norderstedt, Germany), a bispyridine derivative, has broad-spectrum antimicrobial efficacy against Gram-positive and Gram-negative bacteria as well as fungi 33 . While this has mostly been used as an endodontic irrigant, it has recently found utility in the topical care of burn wounds 34 . OCT compounds have demonstrated no impairment of wound healing and lower colonization of bacteria on wound beds 35 .…”

Section: Classificationmentioning

confidence: 99%

Topical Antimicrobials in Burn Care

Cambiaso‐Daniel¹,

Boukovalas²,

Bitz³

et al. 2018

Annals of Plastic Surgery

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Burn wounds disrupt the body’s primary defense against invasion and colonization by microorganisms. Topical antimicrobials are one component in burn wound care. These agents suppress microbial growth to advantage skin cells and wound healing. Topical antimicrobials can be divided into two superclasses: antiseptics and antibiotics. Herein we review the four main classes of topical antiseptics (emulsifiers, acids, oxidizers, and heavy metals) as well as antiseptic-impregnated dressings in current clinical use and address the mechanisms as well as the advantages and disadvantages of each antiseptic for burn wound management.

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“…5,6 In addition to the above-mentioned adverse effect on adhesion, over the years, the antimicrobial property of CHX has been questioned through various studies. 7,8…”

Section: Introductionmentioning

confidence: 99%

Nanotechnology in Dentin Disinfection: Can We Preserve the Bond?

Attiguppe

Tripathi

Sugandhan

et al. 2019

International Journal of Clinical Pediatric Dentistry

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Aims The aim of this study is to evaluate the effect of cavity disinfection with 2% chlorhexidine (CHX) and Ag–Au nanoparticles on microleakage and resin tag penetrability of composite restoration under in vitro conditions. Materials and methods Twenty-five human permanent molars extracted for therapeutic reasons were used in the study. Class V cavity of standard dimension was prepared on the buccal and lingual surfaces of the teeth. The teeth were randomly allocated into two groups based on the cavity disinfectant used: group I being 2% CHX gluconate (chlorhexidina Friedrich and Bianca Mittelstadt (FGM)) and group II being cavity disinfectant containing Ag–Au nanoparticles (nanocare gold). In both the groups, the dentin was etched with 37% phosphoric acid and cavity disinfectants were applied following which dentine bonding agent and composite resin were applied and cured. The specimens were then viewed under a stereomicroscope and a scanning electron microscope for microleakage and resin tag formation, respectively. Results The results were statistically analyzed using an independent “ t ” test. No significant difference was seen between the two groups with respect to both microleakage and resin tag penetration values ( p > 0.05). Conclusion The cavity disinfectant containing Ag–Au nanoparticles did not affect the sealing ability and resin tag penetrability of composite resin in permanent molars when compared with 2% CHX. How to cite this article Attiguppe P, Tripathi AP, et al. Nanotechnology in Dentin Disinfection: Can We Preserve the Bond? Int J Clin Pediatr Dent 2019;12(1):42–46.

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Antimicrobial activity of different disinfectants against cariogenic microorganisms

Cited by 23 publications

References 37 publications

Fatty Acid Evaluation and Antimicrobial Activity of Virgin Coconut Oil and Activated Virgin Coconut Oil on Streptococcus mutans

Fatty Acid Evaluation and Antimicrobial Activity of Virgin Coconut Oil and Activated Virgin Coconut Oil on Streptococcus mutans

Topical Antimicrobials in Burn Care

Nanotechnology in Dentin Disinfection: Can We Preserve the Bond?

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