Tissue characterization following revascularization of immature dog teeth using different disinfection pastes

Pagliarin, Cláudia Medianeira Londero; Londero, Clacir de Lourdes Dotto; Felippe, Mara Cristina Santos; Felippe, Wilson Tadeu; Danesi, Cristiane Cademartori; Barletta, Fernando Branco

doi:10.1590/1807-3107bor-2016.vol30.0074

Cited by 14 publications

(21 citation statements)

References 38 publications

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“…Therefore, considering the results obtained and the principles of sustainability (reduce, reuse, and recycle), this work could contribute to the utilization of BP to obtain films for use in the food and pharmaceutical industries. However, further research is needed to gain a better understanding of the properties and applications of these films 13 Pagliarin et al [23] The results of this study suggest that propolis paste may be a feasible substitute for triple antibiotic paste in the disinfection of root canals of immature teeth with necrotic pulps, with the advantage of not causing changes in tooth color.…”

Section: N°bibliographic Referencementioning

confidence: 84%

“…Conclusions may be due to the propolis chemical composition, which has more active compounds than geopropolis. Since propolis exhibited a better response, further experiments should be carried out both in vitro and in vivo, as treatment with conventional antifungal agents is still problematic 23 Silva et al [33] The acute study revealed no lethal effects at 300 mg/kg of HERP, but toxic signs were observed, as HERP had na LD50 of more than 300 mg/kg, indicating a warning. The most toxic signals in subacute studies were observed in males at a dose of 200 mg/kg HERP.…”

Section: N°bibliographic Referencementioning

confidence: 99%

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Beekeeping in Brazil: A Bibliographic Review

Araújo¹,

Araújo²,

Viana³

et al. 2020

Beekeeping - New Challenges

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Brazil presents favorable conditions for beekeeping, having a suitable climate; native flowering plants with great potential for the production of honey, pollen, propolis, and royal jelly; and bees adapted to our conditions, tolerant to the main apicultural diseases and highly productive. Through the meliponiculture, the conservation of mainly native forest areas is allowed; therefore, they are the best environments for the creation of native bees and production of by-products of the beehive with quality. The stingless bees are very sensitive to any disturbance due to anthropogenic action. A systematic bibliographical review was carried out in different electronic databases, through descriptors referring to beekeeping in Brazil. The identification of articles and their inclusion occurred between January 2018 and April 2018. The bibliographic research was conducted in the following electronic databases: (1) Scientific Electronic Library Online (SciELO), (2) Public Library of Science (PLOS) Biology, and (3) ScienceDirect. In order to help in the process of standardization of bee products and traceability of the production chain, it was possible to draw a profile of the main bioactive substances of the beehive products of Brazil. It was also possible to relate the benefits of an adequate management of beekeeping and meliponiculture in Brazil.

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Section: N°bibliographic Referencementioning

confidence: 84%

Section: N°bibliographic Referencementioning

confidence: 99%

Beekeeping in Brazil: A Bibliographic Review

Araújo¹,

Araújo²,

Viana³

et al. 2020

Beekeeping - New Challenges

View full text Add to dashboard Cite

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“…It was suggested that stem cells of apical papilla (SCAP) can be considered an endogenous cell source for pulp revascularization [23, 27]. However, in cases of loss of apical papilla, which probably occurs with avulsed teeth, stem cells can be migrated from the periapical tissues or from a distance source into the canal space [28].…”

Section: Discussionmentioning

confidence: 99%

Apical Revascularization after Delayed Tooth Replantation: An Unusual Case

Lucisano

Filho

Silva

et al. 2016

Case Reports in Dentistry

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The aim of this paper is to present the clinical and radiological outcome of the treatment involving a delayed tooth replantation after an avulsed immature permanent incisor, with a follow-up of 1 year and 6 months. An 8-year-old boy was referred after dental trauma that occurred on the previous day. The permanent maxillary right central incisor (tooth 11) had been avulsed. The tooth was hand-held during endodontic therapy and an intracanal medication application with calcium hydroxide-based paste was performed. An apical plug with mineral trioxide aggregate (MTA) was introduced into the apical portion of the canal. When the avulsed tooth was replanted with digital pressure, a blood clot had formed within the socket, which moved the MTA apical plug about 2 mm inside of the root canal. These procedures developed apical revascularization, which promoted a successful endodontic outcome, evidenced by apical closure, slight increase in root length, and absence of signs of external root resorption, during a follow-up of 1 year and 6 months.

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“…All the studies considered a beagle dog model and used immature permanent double-rooted teeth from both the upper and lower premolars that had necrotic pulps/apical periodontitis. Alternative antimicrobial strategies to TAP varied from a 3-dimensional (3D) tubularshaped TAP-eluting nanofibrous construct containing 35 mg/mL of each antibiotic 18 to a 1% propolis paste 37 or Qmix solutions composed of CHX, EDTA, and a surfactant detergent 38 . All the teeth were infected following a direct contamination process, ie, the teeth were incorporated with supragingival plaque scaled from the dogs' teeth or they were left open for a certain number of days.…”

Section: Studies That Used An In Vivo Animal Modelmentioning

confidence: 99%

“…All the teeth were infected following a direct contamination process, ie, the teeth were incorporated with supragingival plaque scaled from the dogs' teeth or they were left open for a certain number of days. Two studies 18,37 used a histopathologic analysis to examine the healing outcomes (ie, apical root closure, thickness of the dentin layer, and presence or absence of inflammatory reaction around the apical zone), whereas one study 38 used the CFU analysis to verify the antimicrobial potential of the alternative strategies to reduce bacterial counts as compared with TAP. Overall, the use of both the 3D TAP-eluting construct and propolis paste resulted in similar tooth maturation events when compared with TAP administration and also lower toxicity or potential to provoke inflammatory reactions in the periapical area than TAP.…”

Section: Studies That Used An In Vivo Animal Modelmentioning

confidence: 99%

Antimicrobial Therapeutics in Regenerative Endodontics: A Scoping Review

Ribeiro

Münchow

Bordini

et al. 2020

Journal of Endodontics

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Introduction: This review aimed to provide a critical appraisal of alternative antimicrobial strategies in lieu of traditional triple antibiotic paste (TAP). Methods: This review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. The literature search was performed in 8 databases (PubMed/Medline, Embase, LILACS, Web of Science, Scopus, BVS, SciELO, and the Cochrane Library), selecting clinical, in vitro, in vivo, and in situ studies that evaluated antimicrobial alternatives to TAP in regenerative endodontics. Studies lacking an experimental TAP group were excluded. Results: A total of 1705 potentially relevant records were initially identified. From the 38 studies retrieved for fulltext reading, 16 fulfilled all selection criteria and were included in the qualitative analysis. According to the study design, 11 studies were solely in vitro, 1 study was both in vitro and in vivo (animal model), 2 studies were solely animal experiments, and 2 studies were clinical trials. The alternative antimicrobial agents to TAP consisted of modified TAP formulations (eg, a combination of TAP with chitosan); TAP-eluting nanofibers; propolis; chlorhexidine (CHX) gels/solutions; double antibiotic pastes composed of distinct combinations of antibiotics; Ca(OH) 2-based formulations; and sodium hypochlorite. Overall, most of the alternative agents performed similarly to TAP, although some strategies (eg, Ca(OH) 2-and CHX-based formulations) seemed to present dubious importance in the control of infection. Conclusions: TAP still remains an excellent option in terms of the complete elimination of microorganisms. This review points to the use of electrospun fibers as a drug delivery system to offer a controlled release of the antimicrobial agent, as well as the use of natural compounds, deserving future investigation. (J Endod 2020;46:S115-S127.) KEY WORDS Antimicrobial agents; natural compounds; regenerative endodontics; scoping review Regeneration of pulp tissue holds the promise of prolonged use of the natural dentition through predictable maintenance of dental root structure. Although the field of endodontics has been aware that healthy pulp tissue exists within infected/inflamed pulp, resective therapy has been the standard of care 1. However, in cases where pulp necrosis occurs in permanent teeth with open apex, the most commonly used treatment is apexification 2. This technique is based on the use of calcium hydroxide [Ca(OH) 2 ] or mineral trioxide aggregate (MTA) to induce hard tissue apical barrier formation 3 and presents success rates that vary from 26% to 100%. Nonetheless, the major intrinsic disadvantage of this therapy is that these teeth have thin dentin walls, open apex, and, consequently, an increased risk of cervical fracture 4,5. From a biological viewpoint, Ca(OH) 2 was demonstrated to induce cell proliferation as well as stem cell survival, although only under the use of low concentrations of that compound 6,7. According to Khoshkhounejad et al 8 , cell viability was...

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Tissue characterization following revascularization of immature dog teeth using different disinfection pastes

Cited by 14 publications

References 38 publications

Beekeeping in Brazil: A Bibliographic Review

Beekeeping in Brazil: A Bibliographic Review

Apical Revascularization after Delayed Tooth Replantation: An Unusual Case

Antimicrobial Therapeutics in Regenerative Endodontics: A Scoping Review

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