Anemia in chronic kidney disease

Hazin, Maria Amélia Aguiar

doi:10.1590/1806-9282.66.s1.55

Cited by 18 publications

(17 citation statements)

References 20 publications

(3 reference statements)

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“…Causes of iron deficiency in CKD patients undergoing hemodialysis include repeated phlebotomy, repeated blood tests, and clotting or blood loss in the extracorporeal circuit. [13][14][15] The average levels of ret-he in 50 research subjects were 28.8 ± 3.7 pg, with the highest levels of ret-he at 38.9 pg and the lowest levels of 19.6 pg. Research conducted by Dalimunthe and Lubis (2016) 16 on CKD patients undergoing hemodialysis found that the cutoff ret-he 31.65 pg showed good diagnostic results with a sensitivity of 81.5% and specificity of 61.6%.…”

Section: Resultsmentioning

confidence: 99%

Correlation between Hemoglobin Reticulocytes and Ferritin in Chronic Kidney Disease Patients Undergoing Hemodialysis at PKU Bantul

Shalahuddin

Rosita

2021

J. Berk. Ked

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As many as 7 – 12% of the world's population has chronic kidney disease (CKD). CKD patients can experience various complications, one of which is anemia. Anemia can cause a variety of cardiovascular complications in CKD patients. Enforcement of the diagnosis of anemia and its type is carried out by laboratory examination, among others by examination of reticulocytes-hemoglobin (ret-he) and iron status such as serum ferritin. Examination of these parameters can help in planning the right treatment for CKD patients who have anemia. The purpose of this study was to determine the relationship of Ret-he with ferritin levels in CKD patients undergoing hemodialysis at PKU Bantul Hospital. This study used cross-sectional method. The data source used was secondary data obtained from medical records and the Indonesian Renal Registry (IRR). Sampling research used consecutive sampling method. The analysis used univariate analysis which was frequency distribution table, and bivariate analysis. Univariate analysis obtained that average levels of ret-he from 50 subjects was 28.87 ± 3.75 pg and median serum ferritin levels were 118,1 (9,76 – 1615) mL. Bivariate analysis with pearson correlation test found a significant correlation between serum ret-he and ferritin levels (r = 0.498, p = 0.000).There was a significant correlation between he-ret levels and serum ferritin levels Keywords: chronic kidney disease, anemia, reticulocytes-hemoglobin, serum ferritin.

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Section: Resultsmentioning

confidence: 99%

Correlation between Hemoglobin Reticulocytes and Ferritin in Chronic Kidney Disease Patients Undergoing Hemodialysis at PKU Bantul

Shalahuddin

Rosita

2021

J. Berk. Ked

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“…Embora tratável, percebe-se que a incidência da anemia nos pacientes com DRC aumenta à medida que se avançam os estágios da doença (Hazin, 2020). O fato de a amostra aqui estudada estar acometida majoritariamente por um grave comprometimento da TFG pode explicar as baixas médias de hemoglobina em todas as categorias estudadas.…”

Section: Discussionunclassified

Fatores associados à variação de hemoglobina em mulheres submetidas à hemodiálise

Silva

Andrade

et al. 2021

RSD

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Avaliar os fatores associados ao declínio da hemoglobina em pacientes com DRC. Trata-se de um estudo transversal, conduzido com mulheres submetidas à hemodiálise, excetuando-se as portadoras de doenças hemolíticas. A coleta de dados bioquímicos e antropométricos foram realizadas a partir de prontuário eletrônico das pacientes inseridas na pesquisa. Cerca de 80% das mulheres eram adultas e o agravo crônico de maior prevalência foi a Hipertensão Arterial Sistêmica (75,65%). Foi possível constatar que todas as categorias analisadas apresentaram média de hemoglobina com valor inferior a 12g/dL indicando a anemia como um problema em vigência no público estudado. Os fatores que mostraram associação estatisticamente significativa com os menores níveis de hemoglobina foram: Hipertensão, Diabetes mellitus e o menor tempo em hemodiálise. A presença de outros agravos no portador de Doença Renal Crônica, como diabetes, hipertensão e menor tempo de hemodiálise, contribuem para maior comprometimento dos níveis de hemoglobina.

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“…Individuals with anemia also had less strength in the knee extensor muscles (14.1 vs 15.2 kg; p=0.02) and lower handgrip strength (25.3 vs 27.1 kg; p = 0.04) as compared with individuals without anemia. (35) From the results of a study conducted on elderly patients between 65 and 90 years of age, a significant association was found between hemoglobin concentration and functional status, as assessed with the functional independence measure (FIM). (30) In this study, the FIM score was lower (showing low functional ability) in elderly patients with mild anemia (hemoglobin concentration <12g/dL) as compared with elderly subjects with normal hemoglobin concentration (hemoglobin concentration 12g/dL).…”

Section: Impact Of Anemia On Physical Functions In the Elderlymentioning

confidence: 99%

“…Similarly, functional limitations as a result of anemia were also reported in patients with chronic renal failure. (35) In one other study on elderly females an evaluation was made on the association of hemoglobin concentration and the resulting limitations of mobility, with summary performance score. The incidence of mobility limitations of was not constant in the group of females with normal hemoglobin concentration based on World Health Organization standards (12.0-16.0 g/dL).…”

Section: Impact Of Anemia On Physical Functions In the Elderlymentioning

confidence: 99%

The importance of anemia and health-related quality of life in the elderly

Wratsangka

Putri

2020

Universa Medicina

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Anemia is a global health problem with an extremely high prevalence and occurring in nearly 25% of the world population, particularly in the elderly group. Currently Indonesia is facing a rapid growth of the elderly population, with around 21 million elderly (8.2% of the total population), that is projected to increase to 33.7 million (11.8%) in the year 2025. Anemia in the elderly is frequently neglected, although the facts show that low hemoglobin concentration is an important marker of physiological decline and functional limitations. Although the factor of intrinsic aging may cause low hemoglobin concentration, anemia in the elderly is known to have a wide range w88ith regard to etiology, underlying disorders, and possible mechanisms, such that it should be clinically followed up. Whatever its causes or underlying pathophysiological, anemia in the elderly has been proven to play a role in their morbidity and mortality, and may decrease their quality of life, that comprises all aspects of physical, mental, and social health, known as health-related quality of life (HRQoL). The impact of anemia on HRQoL has been studied in various populations, and most studies report the presence of an association between HRQoL and anemia in elderly individuals, which on the subscale level is particularly associated with physical health. Early diagnosis of anemia is important to prevent aggravation of the condition, to retard the progress of the disease, and to improve the health-related quality of life (HRQoL) of the patient. Prior to determining the treatment plan, the primary diagnosis and the comorbidities, especially treatable disorders, had better be identified first. The available data show that the overall prognosis will improve for anemia in patients with well-managed and corrected chronic disorders.

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Anemia in chronic kidney disease

Cited by 18 publications

References 20 publications

Correlation between Hemoglobin Reticulocytes and Ferritin in Chronic Kidney Disease Patients Undergoing Hemodialysis at PKU Bantul

Correlation between Hemoglobin Reticulocytes and Ferritin in Chronic Kidney Disease Patients Undergoing Hemodialysis at PKU Bantul

Fatores associados à variação de hemoglobina em mulheres submetidas à hemodiálise

The importance of anemia and health-related quality of life in the elderly

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