Index of cardiac-electrophysiological balance and the effects of thrombolytic therapy on the electrocardiogram of patients with pulmonary embolism

Alsancak, Yakup; Sahın, Ahmet Taha; Gürbüz, Ahmet Seyfeddin; Sertdemi̇r, Ahmet Lütfü; İçli̇, Abdullah; Akıllı, Hakan; Düzenli, Mehmet Akif

doi:10.1590/1806-9282.66.12.1657

Cited by 4 publications

(1 citation statement)

References 25 publications

(15 reference statements)

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“…They also observed a significant reduction in calculated iCEB and iCEBc values following thrombolytic therapy in this patient population. Considering the strong association between the impaired right ventricular functions and proarrhythmogenic status in patients with pulmonary embolism, they speculated that improvements in iCEB and iCEBc may predict reverse right ventricular remodeling in high risk following thrombolytic therapy [24]. Results of our study are compatible with the outcomes of previous studies that showed the strong association between the iCEB and increased risk of ventricular arrhythmias.…”

Section: Discussionsupporting

confidence: 90%

Association Between Index of Cardio‐Electrophysiological Balance and Cardiac Remodeling

Duran¹,

Özen²,

BÜYÜKTERZİ³

2022

Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi

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Objective: Pathophysiological changes in response to myocardial infarction (MI) result in cardiac remodeling. Left untreated this pathologic process contributes to impairment of ventricular function and development of malignant ventricular arrhythmias. Recently introduced ECG‐based marker index of cardio‐electrophysiological balance (iCEB) has been shown to be associated with various cardiac conditions. Herein, we aimed to investigate the association between the iCEB and cardiac remodeling in post-MI patients. Material and Methods: Patients aged ≥18 years presenting with acute MI who underwent successful percutaneous coronary intervention between January 2020 and January 2021 were recruited. Regarding the assessment of cardiac remodeling, left ventricular (LV) mass, LV mass index (LVMI), and relative wall thickness (RWT) were measured before the start of treatment and six months after the procedure along with the QT/QRS ratio (iCEB), and QTC/QRS ratio (iCEBc). Results: According to our study, estimated QT/QRS (iECB) and QTc/QRS (iECBc) ratios were found to be significantly lower at six-month follow-up compared to baseline values (4.73∓0.60 vs 4.62∓0.55 & 4.93∓0.59 vs 4.78∓0.55, p

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Section: Discussionsupporting

confidence: 90%

Association Between Index of Cardio‐Electrophysiological Balance and Cardiac Remodeling

Duran¹,

Özen²,

BÜYÜKTERZİ³

2022

Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi

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Index of cardiac-electrophysiological balance in relapsing–remitting multiple sclerosis patients treated with fingolimod

Gunay-Polatkan

Gullu

Sığırlı

et al. 2023

Multiple Sclerosis and Related Disorders

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Clinical Application of Echocardiography in Evaluating Left Ventricular Diastolic Function in Patients with Acute Pulmonary Embolism

Qin

Zhang

2022

Computational and Mathematical Methods in Medicine

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Objective. To explore the clinical application of echocardiography in assessing left ventricular diastolic function in patients with acute pulmonary embolism (APE). Methods. About 90 patients with APE treated in our hospital from March 2016 to March 2019 were enrolled as the study group. The enrolled patients were assigned into three groups in accordance with the risk stratification of APE, with 30 patients in each group, including high-risk group, medium-risk group, and low-risk group. Approximately 90 healthy persons who underwent physical examination in the same period were enrolled as the control group. The two groups were used to analyze the clinical value of echocardiography in evaluating left ventricular diastolic function in patients with APE and to explore the correlation between left ventricular diastolic function and different risk stratification of APE. Results. First of all, we compared the side values of echocardiography. Compared to the control group, right ventricular end-diastolic diameter/left ventricular end-diastolic diameter (RVED/LVED) and pulmonary artery systolic pressure (PASP) in the study group were higher, while left ventricular end-diastolic volume (LVEDV), left ventricular end-systolic volume (LVESV), left ventricular volume per stroke (LVSV), and left ventricular ejection fraction (LVEF) in the study group were lower ( P < 0.05 ). Secondly, we compared the echocardiographic side values of patients with different APE risk stratifications: (1) RVED/LVED, PASP: low ‐ risk group < medium ‐ risk group < high ‐ risk group ; (2) LVEDV, LVESV, LVSV, LVEF: low ‐ risk group > medium ‐ risk group > high ‐ risk group ( P < 0.05 ). The routine echocardiographic findings of APE patients: M-type left ventricular wave group of pulmonary embolism (PE) indicated right ventricular enlargement and interventricular septum shifted to the left ventricle; short-axis section of PE artery indicated thrombosis at the opening of the right pulmonary artery (indicated by arrow); long-axis section of the left ventricle of PE indicated right ventricular enlargement (RV 3.5 cm, LV 3.9 cm); four-chamber view of PE indicated enlargement of the right atrium and the right ventricle, and interventricular septum shifted like left ventricle. In terms of mitral annulus displacement, early diastolic ESD and ELD in the study group were lower compared to those in the normal control group, while late diastolic ASD and ALD in the study group were higher compared to those in the normal control group ( P < 0.05 ). The results of Pearson correlation analysis indicated that there was a positive correlation between RVED/LVED, PASP, and APE risk stratification, while APE risk stratification was negatively correlated with LVEDV, LVESV, LVSV, and LVEF ( P < 0.05 ). Conclusion. Echocardiography attaches importance to the evaluation of left ventricular diastolic function in APE. The side value of echocardiography can sensitively reflect the changes of left ventricular diastolic function in APE. The predictive value in the diagnosis of APE is better than other traditional parameters of left ventricular diastolic function, especially in patients with different APE risk stratifications. There is a remarkable correlation between the changes of left ventricular diastolic function and different APE risk stratifications. Echocardiographic measurement can be employed to assess left ventricular diastolic function in APE, which can be developed in clinical treatment and prognosis evaluation to provide a new evaluation method.

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Index of cardiac-electrophysiological balance and the effects of thrombolytic therapy on the electrocardiogram of patients with pulmonary embolism

Cited by 4 publications

References 25 publications

Association Between Index of Cardio‐Electrophysiological Balance and Cardiac Remodeling

Association Between Index of Cardio‐Electrophysiological Balance and Cardiac Remodeling

Index of cardiac-electrophysiological balance in relapsing–remitting multiple sclerosis patients treated with fingolimod

Clinical Application of Echocardiography in Evaluating Left Ventricular Diastolic Function in Patients with Acute Pulmonary Embolism

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