Public social security burden of musculoskeletal diseases in Brasil-Descriptive study

Passalini, Thaysa Simões Paixão; Fuller, Ricardo

doi:10.1590/1806-9282.64.04.339

Cited by 8 publications

(6 citation statements)

References 5 publications

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“…As doenças osteomusculares e do tecido conjuntivo são um problema não apenas de saúde, mas também social, uma vez que têm alta prevalência em diferentes países e contribuem, significantemente, para as incapacidades entre os adultos, favorecendo os afastamentos precoces do trabalho (24) . As atividades dos servidores operacionais caracterizam-se por trabalhos principalmente manuais e com importante carga física, contribuindo para desenvolvimento das doenças osteomusculares e do tecido conjuntivo.…”

Section: Discussionunclassified

Fatores associados à atividade laboral de técnico-administrativos de universidades estaduais aposentados por invalidez

Moreira,

Martins,

Haddad

et al. 2023

Rev. Gaúcha Enferm.

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RESUMO Objetivo: Verificar os fatores associados ao tipo de atividade laboral exercida por trabalhadores técnico-administrativos universitários aposentados por invalidez. Método: Pesquisa transversal com 68 trabalhadores, realizada por meio de questionário eletrônico entre novembro de 2019 e setembro de 2020. Foram coletados dados sobre a caracterização sociodemográfica, ocupacional e causas da invalidez. Os dados foram analisados descritivamente e por regressões logísticas múltiplas. Resultados: Os profissionais da saúde tiveram mais chances de apresentarem os transtornos mentais e comportamentais, associados ao sexo feminino e independentemente da idade. As chances de doenças do sistema nervoso foram maiores em trabalhadores que exerceram trabalho administrativo, sendo associadas ao ensino superior. Servidores operacionais apresentaram maiores chances de doenças osteomusculares associadas ao ensino fundamental e médio e ao sexo masculino, independentemente da idade. Conclusão: Houve associação da atividade laboral exercida anteriormente à aposentadoria com as doenças responsáveis pela invalidez, com diferenças entre sexo, idade e níveis educacionais.

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Section: Discussionunclassified

Fatores associados à atividade laboral de técnico-administrativos de universidades estaduais aposentados por invalidez

Moreira,

Martins,

Haddad

et al. 2023

Rev. Gaúcha Enferm.

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“…Musculoskeletal disorders are among the leading causes of work disability and sickness absence from work, with some estimates suggesting that the total costs of this disability could be as high as $54 billion annually in the United States alone [31][32]. Other studies have estimated that up to 27% of retirements due to disability are due to musculoskeletal disorders [33].…”

Section: Increased Disability Has a Socioeconomic Impactmentioning

confidence: 99%

The Disability Cascade: A Preventable Consequence of the Loss of Disc Height following Lumbar Microdiscectomy

Kursumovic

Muir

Ammerman

et al. 2019

Cureus

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Lumbar discectomy is a mainstay surgical treatment for herniation of the lumbar discs and is effective at treating radicular symptomology. Despite the overall success of the procedure; the potential for reherniation and reoperation is significant. To avoid this potential recurrence, surgeons often perform discectomy more aggressively, removing a larger volume of nuclear material in the hopes of minimizing the likelihood of reherniation. This approach, while beneficial in minimizing the chance of reherniation, is associated with a volumetric reduction of the nucleus within the disc space, making the disc more prone to collapse and thus inducing a significant post-operative loss of disc height. While potentially minor in isolation, the loss of disc height, in fact, impacts several aspects of overall patient well-being. We hypothesize that the loss of disc height following discectomy causes an increase in pain and subsequent disability, the combination of which ultimately impacts socioeconomic factors affecting both the patient and the healthcare system as a whole. In this report, we outline the evidence in support of this disability cascade and provide recommendations on methods for limiting its impact. Given the current focus on cost-effectiveness in healthcare decision-making, methods for limiting this potentially damaging sequence of events must be investigated.

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“…Inflammation of the synovium and the surrounding joint capsule can also occur. The articular changes cause pain, joint stiffness, and limited joint motion (Gu et al, 2017), strongly impacting the patient's quality of life and the health system (Pasalini and Fuller, 2018).…”

Section: Introductionmentioning

confidence: 99%

Post-Adipose-Derived Stem Cells (ADSC) Stimulated by Collagen Type V (Col V) Mitigate the Progression of Osteoarthritic Rabbit Articular Cartilage

Cruz

Velosa

Carrasco

et al. 2021

Front. Cell Dev. Biol.

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Collagen is essential for cartilage adhesion and formation. In the present study, histology, immunofluorescence, morphometry, and qRT-PCR suggested that adipose-derived stem cells (ADSCs) stimulated by type V collagen (Col V) induce a significant increase of type II collagen (Col II) in the degenerative area of surgical-induced osteoarthritic rabbit articular cartilage (OA). In vitro, the effects of Col V on the proliferation and differentiation of ADSC were investigated. The expression of the cartilage-related genes Col2a1 and Acan was significantly upregulated and Pou5fl was downregulated post-ADSC/Col V treatment. Post-ADSC/Col V treatment, in vivo analyses revealed that rabbits showed typical signs of osteoarthritic articular cartilage regeneration by hematoxylin and eosin (H&E) and Safranin O/Fast Green staining. Immunohistochemical staining demonstrated that the volume of Col II fibers and the expression of Col II protein were significantly increased, and apoptosis Fas ligand positive significantly decreased post-ADSC/Col V treatment. In conclusion, the expression of Col II was higher in rabbits with surgical-induced osteoarthritic articular cartilage; hence, ADSC/Col V may be a promising therapeutic target for OA treatment.

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Public social security burden of musculoskeletal diseases in Brasil-Descriptive study

Abstract: These data point to a progressive increase in the granting of sickness pensions and disability benefits in the country, superior to the growth of the PIA, as well as a high participation of DSOTC in these benefits.

Cited by 8 publications

References 5 publications

Fatores associados à atividade laboral de técnico-administrativos de universidades estaduais aposentados por invalidez

Fatores associados à atividade laboral de técnico-administrativos de universidades estaduais aposentados por invalidez

The Disability Cascade: A Preventable Consequence of the Loss of Disc Height following Lumbar Microdiscectomy

Post-Adipose-Derived Stem Cells (ADSC) Stimulated by Collagen Type V (Col V) Mitigate the Progression of Osteoarthritic Rabbit Articular Cartilage

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