Cerebral aneurysms associated with human immunodeficiency virus in adults: literature review and new perspectives

Abstract

SUMMARY Introduction: the treatment of human immunodeficiency virus (HIV) infection has been decreasing patient morbidity and mortality by opportunistic infections and, thus, survival has increased. This new reality has been changing the spectrum of diseases affecting such patients. Objective: to discuss the association between HIV and the emergence of aneurysmal brain injuries. Method: it was performed a literature review using medical database. The following descriptors were searched: "Intracranial Aneurysms and HIV", "Intracranial Aneurysms and Acquired Immunodeficiency Syndrome," "aneurysm and brain and HIV". Results: after performed a literature review, it was observed that the relationship between HIV infection and the formation of aneurysms appears to be real, however, it still lacks data to confirm the pathophysiology of this condition and its best treatment. Conclusion: there are new signs and symptoms that should be studied and researched relating HIV with other changes not previously known.

The Prevalence of Cerebral Microbleeds in HIV-Infected Hemophilia Patients

“…This finding is compatible with previous reports [21][22][23]. In those reports, chronic inflammation caused by HIV itself or by opportunistic infections was thought to be responsible for vulnerabilities of blood vessels and related to the formation of cerebral aneurysms.…”

Human Immunodeficiency Virus-Associated Multiple Cerebral Aneurysmal Vasculopathy in a Young Adult: A Case Report

“…The actual incidence may be underestimated because patients are asymptomatic in many cases (5). Aneurysmal vasculopathy associated with HIV infection is usually related to fusiform dilatation and occurs in young adults (6). According to a recent systematic review of HIV-associated cerebral aneurysmal vasculopathy cases (16 adults) reported in the literature, the commonly affected arteries were middle cerebral artery (68.8%) followed by the anterior cerebral artery (62.5%) in adults.…”

Intracranial vascular complications in AIDS

“…Опубликованные единичные клинические на-блюдения [63][64][65][66][67] однотипны. Как правило, больных госпитализировали в отделение неотложной помощи с острой неврологической симптоматикой.…”