Vitamin D levels in patients with seborrheic dermatitis

Abstract

SUMMARY OBJECTIVE: Seborrheic dermatitis is a common papulosquamous skin disease with unknown pathogenesis. The aim of our study was to determine the serum level of 25-hydroxy vitamin D in patients with seborrheic dermatitis SD. METHODS: A total of 53 patients and 60 healthy controls were included in the study. Serum vitamin D, calcium, phosphorus, and parathormone levels were measured in the patient and control groups, and a comparison was made between the two groups regarding these parameters. RESULTS: Severe vitamin D deficiency was more frequent among patients with seborrheic dermatitisSD compared to controls (52.8 vs. 25.8%, p=0.003). In patients with severe vitamin D deficiency, seborrheic dermatitis SD was detected more frequently at an early age (p=0048) and in women (p=0.015). No correlation was found between the seborrheic dermatitis skin involvement site and vitamin D level. CONCLUSION: The fact that vitamin D levels decreased in patients with seborrheic dermatitis SD and patients with severe vitamin D deficiency develop seborrheic dermatitis SD earlier suggests that the low levels of vitamin D are related to seborrheic dermatitis.

Association Between Diet and Seborrheic Dermatitis: A Case-Control Study

“…This is supported by a case-control trial comparing the level of 25-hydroxyvitamin D in patients diagnosed with SD to healthy controls, and they've established that serum vitamin D was significantly lower in the SD group (p=0.007) and a low level was also associated with an increased severity of scalp SD (P= 0.003) [19]. Another study investigated the effects of Vitamin D supplementation on recurrences of SD in 32 patients and found that 65% of them had a reduction in the number of disease recurrences during treatment, yet 12.5% suffered an increase in the frequency of disease attacks [20].…”