Clinical prognosis of coronavirus disease 2019 in children and vitamin D levels: a systematic review

24, 2'/exp OR '25-hydroxyvitamin d 2' OR '4-aminobenzoic acid'/exp OR '4-aminobenzoic acid' OR 'acetylcarnitine' OR 'acetylcarnitine'/exp OR acetylcarnitine OR 'alphatocopherol'/exp OR 'alpha-tocopherol' OR 'aminobenzoic acids'/exp OR 'aminobenzoic acids' OR 'ascorbic acid'/exp OR 'ascorbic acid' OR 'beta carotene'/exp OR 'beta carotene' OR 'beta-tocopherol'/exp OR 'beta-tocopherol' OR 'be-ta-tocopherol' OR 'biotin' OR 'biotin'/exp OR biotin OR 'boron' OR 'boron'/exp OR boron OR 'cadmium' OR 'cadmium'/exp OR cadmium OR 'calcifediol' OR 'calcifediol'/exp OR calcifediol OR 'calcitriol' OR 'calcitriol'/exp OR calcitriol OR 'carnitine' OR 'carnitine'/exp OR carnitine OR 'cholecalciferol' OR 'cholecalciferol'/exp OR cholecalciferol OR 'chromium' OR 'chromium'/exp OR chromium OR 'cobalt' OR 'cobalt'/exp OR cobalt OR 'cobamides' OR 'cobamides'/exp OR cobamides OR 'cod liver oil'/exp OR 'cod liver oil' OR 'copper' OR 'copper'/exp OR copper OR 'dehydroascorbic acid'/exp OR 'dehydroascorbic acid' OR 'dihydrotachysterol' OR 'dihydrotachysterol'/exp OR dihydrotachysterol OR 'dihydroxycholecalciferols' OR 'dihydroxycholecalciferols'/exp OR dihydroxycholecalciferols OR 'ergocalciferols' OR 'ergocalciferols'/exp OR ergocalciferols OR 'flavin mononucleotide'/exp OR 'flavin mononucleotide' OR 'folic acid'/exp OR 'folic acid' OR 'formyltetrahydrofolates'/exp OR 'formyltetrahydrofolates' OR 'fursultiamin' OR 'fursultiamin'/exp OR fursultiamin OR 'gamma-tocopherol'/exp OR 'gamma-tocopherol' OR 'hydroxocobalamin' OR 'hydroxocobalamin'/exp OR hydroxocobalamin OR 'hydroxycholecalciferols' OR 'hydroxycholecalciferols'/exp OR hydroxycholecalciferols OR 'inositol' OR 'inositol'/exp OR inositol OR 'iodine' OR 'iodine'/exp OR iodine OR 'iron' OR 'iron'/exp OR iron OR 'leucovorin' OR 'leucovorin'/exp OR leucovorin OR 'manganese' OR 'manganese'/exp OR manganese OR 'magnesium' OR 'magnesium'/exp OR magnesium OR 'molybdenum' OR 'molybdenum'/exp OR molybdenum OR 'niacin' OR 'niacin'/exp OR niacin OR 'niacinamide' OR 'niacinamide'/exp OR niacinamide OR 'nickel' OR 'nickel'/exp OR nickel OR 'nicorandil' OR 'nicorandil'/exp OR nicorandil OR 'nicotinic acids'/exp OR 'nicotinic acids' OR 'palmitoylcarnitine' OR 'palmitoylcarnitine'/exp OR palmitoylcarnitine OR 'pantothenic acid'/exp OR 'pantothenic acid' OR 'pteroylpolyglutamic acids'/exp OR 'pteroylpolyglutamic acids' OR 'pyridoxal' OR 'pyridoxal'/exp OR pyridoxal OR 'pyridoxal phosphate'/exp OR 'pyridoxal phosphate' OR 'pyridoxamine' OR 'pyridoxamine'/exp OR pyridoxamine OR 'pyridoxine' OR 'pyridoxine'/exp OR pyridoxine OR 'riboflavin' OR 'riboflavin'/exp OR riboflavin OR 'selenium' OR 'selenium'/exp OR selenium OR 'silicon' OR 'silicon'/exp OR silicon OR 'tetrahydrofolates' OR 'tetrahydrofolates'/exp OR tetrahydrofolates OR 'thiamine' OR 'thiamine'/exp OR thiamine OR 'thiamine monophosphate'/exp OR 'thiamine monophosphate' OR 'thiamine pyrophosphate'/exp OR 'thiamine pyrophosphate' OR 'thiamine triphosphate'/exp OR 'thiamine triphosphate' OR 'thioctic acid'/exp OR 'thioctic acid' OR 'tin' OR 'tin...

show abstract

The Clinical Significance of Vitamin D and Zinc Levels with Respect to Immune Response in COVID-19 Positive Children

Doğan

Uyanık

et al. 2022

Journal of Tropical Pediatrics

View full text Add to dashboard Cite

Aim In this study, we aimed to evaluate serum vitamin D and zinc levels in children diagnosed with coronavirus disease 2019 (COVID-19). Materials and methods In this study, 88 children with COVID-19 disease and 88 healthy children aged 1–18 years were enrolled between 01 July 2021 and 30 October 2021 in the Pediatrics Clinic of Tekirdağ Çorlu State Hospital. Serum vitamin D and zinc levels have been measured and NCSS (Number Cruncher Statistical System) program has been utilized for statistical analysis. Results We included 88 COVID-19 positive pediatric patients [50% (n = 44) female] and 88 healthy children [48.86% (n = 43) female] in this study. The mean serum vitamin D levels of COVID-19 positive patients were statistically significantly lower than the control group (p = 0.0001). The zinc mean values of the study group were found to be statistically significantly lower than the control group (p = 0.0001). There was a statistically significant correlation between serum vitamin D and zinc values in all patient groups (r = 0.245, p = 0.001). Conclusion As a result, zinc and vitamin D levels were observed lower in COVID-19 patients than in healthy individuals. Since there is no defined treatment protocol for COVID-19 infection on children yet, zinc and vitamin D supplementation can be used as a supportive treatment in COVID-19 infection.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

hi@scite.ai

334 Leonard St

Brooklyn, NY 11211

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Clinical prognosis of coronavirus disease 2019 in children and vitamin D levels: a systematic review

Cited by 3 publications

References 8 publications

The association of serum levels of vitamin D, Zn, and Mg and disease severity in children and adolescents with COVID-19: A case-control study

The association of serum levels of vitamin D, Zn, and Mg and disease severity in children and adolescents with COVID-19: A case-control study

Micronutrient perspective on COVID-19: Umbrella review and reanalysis of meta-analyses

The Clinical Significance of Vitamin D and Zinc Levels with Respect to Immune Response in COVID-19 Positive Children

Contact Info

Product

Resources

About