Physical properties and biological effects of mineral trioxide aggregate mixed with methylcellulose and calcium chloride

Lee, Bin-Na; Chun, Soo-Ji; Chang, Hoon-Sang; Hwang, Yun-Chan; Hwang, In-Nam; Oh, Won-Mann

doi:10.1590/1678-7757-2017-0050

Cited by 9 publications

(3 citation statements)

References 31 publications

(37 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Furthermore, according to the results of the compressive strength test after 1 day, C12A7-5 showed higher early strength compared to C12A7-0. The compressive strength values obtained in this study were higher than those of MTA in another previous study 20 . The results indicated that the addition of C12A7 might be beneficial for the early strength of the cement.…”

Section: Discussioncontrasting

confidence: 50%

Effects of dodecacalcium hepta-aluminate content on the setting time, compressive strength, alkalinity, and cytocompatibility of tricalcium silicate cement

et al. 2019

View full text Add to dashboard Cite

ObjectiveThis study aimed to investigate the effects of dodecacalcium hepta-aluminate (C12A7) content on some physicochemical properties and cytocompatibility of tricalcium silicate (C3S) cement using human dental pulp cells (hDPCs).Material and MethodsHigh purity C3S cement was manufactured by a solid phase method. C12A7 was mixed with the cement in proportions of 0, 5, 8, and 10 wt% (C12A7-0, −5, −8, and −10, respectively). Physicochemical properties including initial setting time, compressive strength, and alkalinity were evaluated. Cytocompatibility was assessed with cell viability tests and cell number counts. Statistical analysis was performed by using one-way analysis of variance (ANOVA) and Tukey's test (p<0.05).ResultsThe initial setting time of C3S-based cement was shorter in the presence of C12A7 (p<0.05). After 1 day, C12A7-5 showed significantly higher compressive strength than the other groups (p<0.05). After 7 days, the compressive strength of C12A7-5 was similar to that of C12A7-0, whereas other groups showed strength lower than C12A7-0. The pH values of all tested groups showed no significant differences after 1 day (p>0.05). The C12A7-5 group showed similar cell viability to the C12A7-0 group (p>0.05), while the other experimental groups showed lower values compared to C12A7-0 group (p<0.05). The number of cells grown on the C12A7-5 specimen was higher than that on C12A7-8 and −10 (p<0.05).ConclusionsThe addition of C12A7 to C3S cement at a proportion of 5% resulted in rapid initial setting time and higher compressive strength with no adverse effects on cytocompatibility.

show abstract

Section: Discussioncontrasting

confidence: 50%

Effects of dodecacalcium hepta-aluminate content on the setting time, compressive strength, alkalinity, and cytocompatibility of tricalcium silicate cement

et al. 2019

View full text Add to dashboard Cite

show abstract

“…Some authors tested modified MTA cements by incorporating different additives in order to improve their physical and biological performances; however, the results we have collected do not entirely support this supposition, especially concerning histological results. The addition of calcium chloride or amorphous calcium lactate gluconate-based liquid accelerated the setting reaction and improved handling, while the addition of propylene glycol provided a higher pH, with antibacterial effect [ 139 ], better flowability and increased calcium release [ 140 ]. There were no significant differences concerning acute inflammation between MTA with or without calcium chloride as DPC agents; however, MTA with calcium chloride showed a higher chronic inflammatory response, and the quality of the dentin bridge was inferior [ 92 ].…”

Section: Discussionmentioning

confidence: 99%

The Effect of Calcium-Silicate Cements on Reparative Dentinogenesis Following Direct Pulp Capping on Animal Models

et al. 2021

View full text Add to dashboard Cite

Dental pulp vitality is a desideratum for preserving the health and functionality of the tooth. In certain clinical situations that lead to pulp exposure, bioactive agents are used in direct pulp-capping procedures to stimulate the dentin-pulp complex and activate reparative dentinogenesis. Hydraulic calcium-silicate cements, derived from Portland cement, can induce the formation of a new dentin bridge at the interface between the biomaterial and the dental pulp. Odontoblasts are molecularly activated, and, if necessary, undifferentiated stem cells in the dental pulp can differentiate into odontoblasts. An extensive review of literature was conducted on MedLine/PubMed database to evaluate the histological outcomes of direct pulp capping with hydraulic calcium-silicate cements performed on animal models. Overall, irrespective of their physico-chemical properties and the molecular mechanisms involved in pulp healing, the effects of cements on tertiary dentin formation and pulp vitality preservation were positive. Histological examinations showed different degrees of dental pulp inflammatory response and complete/incomplete dentin bridge formation during the pulp healing process at different follow-up periods. Calcium silicate materials have the ability to induce reparative dentinogenesis when applied over exposed pulps, with different behaviors, as related to the animal model used, pulpal inflammatory responses, and quality of dentin bridges.

show abstract

“…Despite many known advantages of MTA, its disadvantages include color change, long curing time, low fluidity and usage difficulties (ElReash et al, 2019). For this reason, efforts are underway to improve MTA's physical properties (Lee et al, 2017; Natu et al, 2015).…”

Section: Introductionmentioning

confidence: 99%

In vitro comparison of physical, chemical, and mechanical properties of graphene nanoplatelet added Angelus mineral trioxide aggregate to pure Angelus mineral trioxide aggregate and calcium hydroxide

KÜÇÜKYILDIZ

Dayi

Altın

et al. 2021

Microscopy Res & Technique

View full text Add to dashboard Cite

It is important to cover the pulp surface with a biocompatible material that is physically, mechanically, and chemically adequate. Graphene has the potential to form hard tissue, but at high doses, it shows toxic effects. It can be added to biocompatible materials at low doses to enhance their hard tissue forming potential. The aim of this study was to compare the physical, chemical, and mechanical properties of graphene nanoplatelet (GNP) added Angelus mineral trioxide aggregate (A‐MTA) to pure A‐MTA and calcium hydroxide. Homogeneous mixtures (created by adding +0.1 weight[wt]% and 0.3 wt% GNP to A‐MTA), pure A‐MTA, and Dycal were used. Three disc‐shaped samples of each material were prepared using Teflon mold. Scanning electron microscope–energy dispersive X‐ray (SEM–EDX), particle size, microhardness, and Fourier transform infrared spectroscopy (FTIR) analysis of the materials were performed in vitro. Data were analyzed using Kruskal–Wallis test followed by Conover test (p < .001). A‐MTA and GNP added samples showed similar peaks in FTIR analysis. In the EDX analysis, the amount of carbon was observed with a higher increase at A‐MTA + 0.3 wt% GNP than A‐MTA + 0.1 wt% GNP. In the SEM image, hollow structure and particle size decreased as the amount of GNP increased; particle size was smaller at A‐MTA + 0.3 wt% GNP than A‐MTA + 0.1 wt% GNP (p < .001). A‐MTA + 0.3 wt% GNP showed the highest microhardness while Dycal showed the lowest microhardness. The addition of GNP, a material with high potential for forming hard tissue, to the structure of capping materials can also positively contribute to the microhardness of the capping materials.

show abstract

Physical properties and biological effects of mineral trioxide aggregate mixed with methylcellulose and calcium chloride

Cited by 9 publications

References 31 publications

Effects of dodecacalcium hepta-aluminate content on the setting time, compressive strength, alkalinity, and cytocompatibility of tricalcium silicate cement

Effects of dodecacalcium hepta-aluminate content on the setting time, compressive strength, alkalinity, and cytocompatibility of tricalcium silicate cement

The Effect of Calcium-Silicate Cements on Reparative Dentinogenesis Following Direct Pulp Capping on Animal Models

In vitro comparison of physical, chemical, and mechanical properties of graphene nanoplatelet added Angelus mineral trioxide aggregate to pure Angelus mineral trioxide aggregate and calcium hydroxide

Contact Info

Product

Resources

About