Caries progression in non-cavitated fissures after infiltrant application: a 3-year follow-up of a randomized controlled clinical trial

Abstract

Objectives To evaluate the efficacy of a conservative treatment to prevent the progression of caries using an infiltrant on non-cavitated pit and fissures.Material and Methods This controlled clinical trial selected 23 volunteers with clinically and radiographically non-cavitated occlusal caries among patients presenting a “rather low” to “very high” caries risk. Eighty-six teeth were randomly divided into two experimental groups: teeth receiving a commercial pit-and-fissure sealant (Alpha Seal-DFL) and contralateral teeth receiving Icon infiltrant (DMG). Caries progression was monitored by clinical (laser fluorescence caries detection) and radiographic examination at 12-month intervals over a period of 3 years of monitored caries progression. Probing the sealing materials to detect areas of retention was also used to evaluate marginal integrity.Results Statistical analysis showed no difference in caries progression using laser fluorescence caries detection when both materials were compared, regardless of the evaluation times (p>0.05). No significance was observed when the marginal sealant integrity of both materials was compared, regardless of the evaluation time (p<0.05). Marginal integrity significantly reduced after 1 year for both materials (p<0.05), but remained stable after 2 and 3 years of evaluation, compared with 1-year results (p>0.05). SEM analysis exhibited a more homogeneous sealing for the infiltrant than obtained by the sealant.Conclusions The infiltrant was effective to prevent the caries progression in non-cavitated pit-and-fissures after 3 years of clinical evaluation, comparable with the conventional sealant. The infiltrant also presented better results in terms of caries progression at the 3-year evaluation time using the radiographic analysis.

Effects of different resin sealing therapies on nanoleakage within artificial non-cavitated enamel lesions

“…A very recent clinical study also supported our findings that a TEGDMA containing commercial fissure sealant and ICON infiltrant were both effective to prevent the caries progression in non-cavitated pitand-fissures after 3 years. However, marginal integrity of the lesions was significantly reduced after 1 year for both materials 40) .…”

Laser fluorescence as an alternative for digital radiography in detecting caries lesions

“…18,19 More recent research suggests complementing this method with photosensitizers and thus increasing the sensitivity and specificity of the The FC device showed good performance with Considering ethical concerns, some studies including in vivo samples used BW (bitewing) as a gold standard 3,9,12,30-32 and others used ICDAS. 10,33 Based on their results Melo et al, 9 Menem et al, 30 Bizhang et al 31 affirms that DIAGNOpen is an alternative to avoid ionizing radiation for the patients, but despite having similar findings, Schwendicke et al 12 and Anauate-Neto et al 32 indicates it only as a complement.…”

Annual review of selected scientific literature: A report of the Committee on Scientific Investigation of the American Academy of Restorative Dentistry

“…The second study evaluated an infiltrating resin on caries progression in noncavitated pit and fissure lesions. 307 Eighty-six teeth with noncavitated occlusal caries were randomly assigned to either a commercial pit and fissure sealant (Alpha Seal-DFL) or Icon infiltrant (DMG). Caries progression was monitored at 12-month intervals for 3 years by laser fluorescence and radiographs.…”