Conidiobolomycosis in goats

Abstract

The present article presents cases of conidiobolomycosis in adult goats with clinical signs characterized by serous nasal discharge, dyspnea, apathy, and weight loss. Two goats were necropsied. Necropsy displayed increased volume on the sagittal section of the head and an ulcerated surface containing a yellow friable mass with irregular and granular consistency in the nasal septum and in the ventral nasal turbinate. One goat also presented lesions on the ear’s skin and the right pelvic limb. Microscopically, lesions were characterized by multifocal granulomas with a central necrotic area containing non-stained fungal hyphae images surrounded by a granulomatous infiltrate. Samples of the lesions examined by immunohistochemistry and polymerase chain reaction were positive for Conidiobolus lamprauges. This is the first report of conidiobolomycosis in goats, and the disease should be considered in the differential diagnoses for rhinitis and dermatitis in goats.

Facial and systemic mucormycosis caused by Lichtheimia corymbifera in a goat: case report and literature review of fungal infections in goats

“…4 Exserohilum rostratum , a dematiaceous fungus, plant pathogen, and cause of an outbreak of fungal meningitis in people associated with contaminated methylprednisolone injections, 35 has been reported as a cause of rhinitis in a goat in Brazil. 6 As previously mentioned, there is a report of Conidiobolus facial mycosis in 2 goats from Brazil, 23 but none of basidiobolomycosis based on PubMed and Google searches. Systemic fungal infection tentatively identified as sterile fungi, a group of fungi without reproductive cells or conidia, that also involved the nasal cavity was reported in a Tur goat.…”

“…15,33 In our case, the lesion extensively involved the maxillary molar, hard palate, and nasal cavity, similar to the lesions described in rhinofacial entomophthoramycosis caused by Conidiobolus spp. in sheep, 10 rarely goats, 23 and people, 1 and rhino-cerebro-orbital mucormycosis of people. 31 Additionally, secondary vascular dissemination to the local lymph nodes, lungs, and kidneys was identified.…”