Ultrasonic-extraction of phenolic compounds from Phyllanthus urinaria: optimization model and antioxidant activity

Liu, Yong; She, Xia-Rong; Huang, Jia-Bin; Liu, Min-Chun; Zhan, Min-Er

doi:10.1590/1678-457x.21617

Cited by 27 publications

(19 citation statements)

References 36 publications

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“…The ranges and central point values of two process variables are shown in Table 1. The ranges of ethanol concentration (60-96%) and sonication time (10-30 min) were selected based on literature findings (Jeszka-Skowron et al, 2014;Liu et al, 2018) and the authors' previous experiments.…”

Section: Experimental Design and Statistical Analysis Rsmmentioning

confidence: 99%

Optimisation of ultrasonic-assisted extraction of bioactive compounds from chokeberry pomace using response surface methodology

Sady

Matuszak

Błaszczyk

2019

Acta Sci Pol Technol Aliment

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0000-0002-4744-9361, phone +48 61 856 9022 www.food.actapol.net pISSN 1644-0730 eISSN 1898-9594 http://dx. ABSTRACTBackground. Chokeberry pomace is a valuable by-product of fruit processing because of its high levels of phenolic compounds and anthocyanins. The study was aimed to optimise chokeberry pomace extraction of total phenolic content, total anthocyanin content and antioxidant activity using response surface methodology. Material and methods. Response surface methodology was used to evaluate the effect of the concentration of ethanol (in the range of 60-96%) and sonication time (from 10 to 30 min) as independent variables on total phenolic content, antioxidant capacity and total anthocyanin content as the response functions.Results. The results showed that ethanol concentration, but not sonication time, had a significant influence on total phenolic content, antioxidant activity and total anthocyanin content. The optimal extraction conditions for total phenolic content (188.5 mg GAE/g DM) and antioxidant capacity (49.2 mM Tr/100 g DM) were 60% ethanol and 20 min sonication time. The optimal conditions in the case of total anthocyanin content (89.3 mg C3GE/g) were an 65% ethanol concentration and 13 min sonication time.Conclusion. The development of optimal extraction parameters should allow food producers to use efficient, cost-effective and environmentally friendly technology to isolate biologically active molecules from chokeberry pomace, while the selected extract could be a component of health-promoting bioactive products.Keywords: response surface methodology, chokeberry pomace, ultrasonic-assisted extraction, total phenolic content, antioxidant activity, total anthocyanin content Sady, S., Matuszak, L., Błaszczyk, A. (2019). Optimisation of ultrasonic-assisted extraction of bioactive compounds from chokeberry pomace using response surface methodology. Acta Sci. Pol. Technol. Aliment., 18(3), 249-256. http://dx.

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Section: Experimental Design and Statistical Analysis Rsmmentioning

confidence: 99%

Optimisation of ultrasonic-assisted extraction of bioactive compounds from chokeberry pomace using response surface methodology

Sady

Matuszak

Błaszczyk

2019

Acta Sci Pol Technol Aliment

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“…The highest significance level of ethanol concentration might be due to the fact that its concentration can make extraction solution to have a varied polarity that can enhance the leaching of phenolic compounds from V. cinerea leaves (Spigno and De Faveri, 2009). In addition, feed/solvent enhances the mass concentration difference between outside and inside of plant sample which might result in the improvement of mass transport driving force and rate of internal diffusion (Liu et al, 2017). Moreover, Figures 2 and 3 outline the relationships between the TPC, TFC and most significant MAE variables.…”

Section: 4mentioning

confidence: 99%

Two Level Factorial Screening of Microwave-Assisted Extraction Parameters for the Recovery of Phenolic Compounds From Vernonia Cinerea Leaf

Alara¹,

Abdurahman²,

Alara³

2019

JCEIB

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Vernonia cinerea is one of the medicinal plants with several potentials for treating different ailments. In the present study, Microwave-assisted extraction (MAE) was employed in extracting phenolics compounds from this plant. However, different factors that affect this extraction method in the recovery of phenolics compounds abound, these factors need to be screened to determine actual contributing factor in order to minimize cost. Irradiation time (1-5 min), ethanol concentration (20-60% v/v), microwave power (40-80 W), extraction temperature (40-80 oC), and feed/solvent (1:10 - 1:18 g/mL) have been screened using two-factorial design for the recoveries of phenolic compounds from V. cinerea leaves. The results obtained in this study indicated that only microwave power, ethanol concentration, irradiation time and feed/solvent contributed to recoveries of total phenolic content (TPC) and total flavonoid content (TFC) from V. cinerea leaves. Thus, these factors at these ranges can be further optimized to obtain optimal yields of phenolic compounds from V. cinerea leaves.

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“…The aqueous extract (AE) and hydroalcoholic extract (HAE) were prepared by combining 5 g leaves and 100 mL water or hydroalcoholic solution (50 water and 50% ethanol), respectively, and then sonicated in an ultrasonic bath at 40 KHz for 25 min. at 45°C (Liu, She, Huang, Liu, & Zhan, 2017). Solutions were filtered, and the filtrate was concentrated to dryness under reduced pressure in a rotator evaporator.…”

Section: Plant Extract Preparationmentioning

confidence: 99%

Protective role of <i>Syzygium cumini</i> leaf extracts against paraquat-induced oxidative stress in superoxide-dismutase-deficient<i> Saccharomyces cerevisiae</i> strains

Soares

Rosa

Motta

et al. 2019

Acta Sci. Biol. Sci.

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The aim of this study was to evaluate the protective effect of three different extracts prepared from Syzygium cumini leaves against paraquat-induced toxicity in Saccharomyces cerevisiae strains deficient in superoxide dismutase (SOD). Additionally, the extracts phenolic and flavonoid contents, in vitro antioxidant activity, and phytochemical composition (using high-pressure liquid chromatography) were determined. Bioactive compounds from S. cumini leaves were extracted with infusion (traditional method) or ultrasound (aqueous or hydroalcoholic). Compared to the infusion extract, the ultrasound extracts exhibited a greater protective capacity against paraquat toxicity in the yeast cells as well as higher antioxidant activity. These results may be directly related to the higher phenolic and flavonoid contents in these extracts, since they are recognized as having high antioxidant actions.

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Ultrasonic-extraction of phenolic compounds from Phyllanthus urinaria: optimization model and antioxidant activity

Cited by 27 publications

References 36 publications

Optimisation of ultrasonic-assisted extraction of bioactive compounds from chokeberry pomace using response surface methodology

Optimisation of ultrasonic-assisted extraction of bioactive compounds from chokeberry pomace using response surface methodology

Two Level Factorial Screening of Microwave-Assisted Extraction Parameters for the Recovery of Phenolic Compounds From Vernonia Cinerea Leaf

Protective role of <i>Syzygium cumini</i> leaf extracts against paraquat-induced oxidative stress in superoxide-dismutase-deficient<i> Saccharomyces cerevisiae</i> strains

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