Beneficial effects of coconut oil (Cocos nucifera) on hematobiochemicl and histopathological markers in CCL4-intoxicated rabbits

Abstract

The study was designed to investigate the effect of Coconut Oil on the levels of some liver and hematological parameters in carbon tetrachloride intoxicated rabbits. Also the antioxidant capacity of Coconut Oil for various concentrations was assessed on the basis of percent scavenging of (DPPH) free radical. Experimental animals were divided into five groups, eight rabbits in each group. These were: group A (Normal control), group B (Toxic control), group C (Standard control), group D (Treated with Coconut Oil 50 mL/kg body weight after CCl4 intoxication), group E (Treated with Coconut Oil 200 mL/kg body weight after CCl4 intoxication). The effects observed were compared with a standard hepatoprotective drug silymarine (50 mL/kg body weight). The Coconut Oil (200 mL/kg body weight) significantly (P<0.05) reduced the elevated serum levels of alanine transaminase (ALT), aspartate transaminase (AST) and alkaline phosphatase (ALP) when compared to a toxic control rabbits. The results of extract treated rabbits were similar to silymarine administered rabbits group. Treatment with Coconut Oil root and silymarine caused no significant changes in RBC, Platelets, (Hb), (MCH) concentration and (HCT) values. However, significant (P<0.05) increase was observed in the total WBC count. The present study suggested that Coconut Oil can be used as an herbal alternative (need further exploration i.e to detect its bioactive compound and its efficacy) for hepatoprotective activity.

Los beneficios que aporta el aceite de coco a la salud bucal.

“…El aceite de coco es proveniente de origen vegetal (cocos nucifera), el cual se extrae de la porción de la pulpa blanca que va a cubrir la parte interna de la nuez; un método es ponerlo a presión en la porción carnosa de color blanca, el cual contiene un 60% de aceite láurico, sometiéndolo a temperatura ambiente y se solidifica porque contiene el 92% de ácidos grasos, al ser una sustancia con una gran cantidad de grasa tiene un proceso de oxidación ralentizado, haciendo que este producto no necesite de conservantes, ya que a temperatura ambiente puede mantenerse fresco durante 6 meses, comprobando la gran autoconservación de este producto (Ahmad et al, 2022); por tal razón, nos hemos basado en el seguimiento de este extracto natural para obtener beneficios para la creación de futuros productos de higiene oral a base de éste, aportando como un gran beneficio la prevención de caries, evitando la reproducción de los gérmenes en la boca, gracias a su ácido láurico que ayuda a la reducción y bloquea la formación de las bacterias como el estreptococo.…”