Prevalence of pharmacological adherence in patients with coronary artery disease and associated factors

Padilha, Jaqueline Correia; Santos, Vinícius Batista; Lopes, Camila Takáo; Lopes, Juliana de Lima

doi:10.1590/1518-8345.4554.3464

Cited by 7 publications

(5 citation statements)

References 30 publications

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“…Nonadherence involves the failure of a patient to take medications appropriately due to personal factors [23]. Several studies have indicated that roughly 20% and more than 50% of CAD patients are non-adherent to prescribed medications [48][49][50]. Many factors can affect patient adherence to treatment: lack of motivation, failure to understand instructions, forgetfulness, the complexity of the regimen, polypharmacy, multiple daily doses, adverse side effects, high cost, failure to initiate treatment before discharge, and the physician's lack of knowledge of clinical indicators for the use of medications [51,52].…”

Section: Patient Nonadherencementioning

confidence: 99%

Drug-Related Problems in Coronary Artery Diseases

Tran¹,

Nguyen²,

Tran³

et al. 2022

Coronary Artery Bypass Grafting

107

163

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Coronary artery disease (CAD) remains the leading cause of mortality among cardiovascular diseases, responsible for 16% of the world’s total deaths. According to a statistical report published in 2020, the global prevalence of CAD was estimated at 1655 per 100,000 people and is predicted to exceed 1845 by 2030. Annually, in the United States, CAD accounts for approximately 610,000 deaths and costs more than 200 billion dollars for healthcare services. Most patients with CAD need to be treated over long periods with a combination of drugs. Therefore, the inappropriate use of drugs, or drug-related problems (DRPs), can lead to many consequences that affect these patients’ health, including decreased quality of life, increased hospitalization rates, prolonged hospital stays, increased overall health care costs, and even increased risk of morbidity and mortality. DRPs are common in CAD patients, with a prevalence of over 60%. DRPs must therefore be noticed and recognized by healthcare professionals. This chapter describes common types and determinants of DRPs in CAD patients and recommends interventions to limit their prevalence.

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Section: Patient Nonadherencementioning

confidence: 99%

Drug-Related Problems in Coronary Artery Diseases

Tran¹,

Nguyen²,

Tran³

et al. 2022

Coronary Artery Bypass Grafting

107

163

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“…Alarmingly, our population also demonstrated the lowest rate of medication use for HTN at just 40.9%, lower than Pakistan’s 52.9% [ 8 ]. This underuse of medication, coupled with the common misperception among patients about correct medication usage [ 36 ], suggests that the actual burden of HTN may be greater than reported.…”

Section: Discussionmentioning

confidence: 99%

Coronary artery disease incidence, risk factors, awareness, and medication utilization in a 10-year cohort study

Sarebanhassanabadi,

Mirjalili,

Marques-Vidal

et al. 2024

BMC Cardiovasc Disord

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Background There is a substantial disparity in coronary artery disease (CAD) burden between Iran and other nations that place a strong emphasis on the assessment of CAD risk factors and individuals’ awareness and ability to control them. Methods Two thousand participants of a community-based Iranian population aged 20–74 years were investigated with a mean follow-up of 9.9 years (range: 7.6 to 12.2). An analysis of Cox regression was conducted to determine the association between CAD development and classic risk factors such as age, sex, smoking, physical activity, education, obesity, dyslipidemia, hypertension, and diabetes mellitus. Furthermore, we computed the population attributable fraction for these risk factors. Results After a follow-up period of nearly 10 years, 225 CAD events were reported, constituting 14.5% of the overall incidence. Nighty three percent of participants had more than one risk factor. Age was the most predictive risk factor, with a hazard ratio (HR) and confidence interval (CI) of 5.56 (3.87–7.97, p < 0.001) in men older than 45 and females older than 55 compared to lower ages. In comparison to females, males had an HR of 1.45 (CI: 1.11–1.90, p value = 0.006) for developing CAD. Nearly 80% of the patients had dyslipidemia, with a hazard ratio of 2.19 (CI: 1.40–3.44, p = 0.01). Among the participants, 28.9% had hypertension, and 52% had prehypertension, which had HRs of 4.1 (2.4–7.2, p < 0.001) and 2.4 (1.4–4.2, p < 0.001), respectively. Diabetes, with a prevalence of 17%, had an HR of 2.63 (CI: 2 -3.47, p < 0.001), but prediabetes was not significantly associated with CAD. Awareness of diabetes, dyslipidemia, and hypertension was 81%, 27.9%, and 48.1%, respectively. Regarding medication usage, the corresponding percentages were 51% for diabetes, 13.2% for dyslipidemia, and 41% for hypertension. Conclusions Compared to previous studies in Iran and neighboring countries, the current study found a higher incidence of CAD, more prevalent risk factors, and a lower awareness and ability to control these risk factors. Thus, an effective preventive strategy is needed to reduce the CAD burden in Iran.

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“…(25) No tópico "medicamentos utilizados", sugeriu--se adicionar alguns efeitos adversos relacionados às medicações utilizadas nessa população, principalmente a tontura e a sonolência, e orientações sobre como proceder na presença desses sintomas. Essa informação é de extrema relevância, já que um dos motivos de não adesão ao tratamento farmacológico é a presença de efeitos adversos relacionados aos medicamentos, (29) e o indivíduo ao conhecer como proceder a esses possíveis efeitos colaterais mantém o seu tratamento. (26) No que se refere à "atividade sexual", sugeriu--se adicionar outros medicamentos utilizados para o controle da impotência sexual, além do Sildenafil, como contraindicações aos pacientes que fazem uso de nitratos.…”

Section: Discussionunclassified

Educação em saúde para pacientes submetidos à revascularização miocárdica: validação de história em quadrinhos

Queiroz¹,

Russomanno²,

Santos³

et al. 2022

Acta Paulista De Enfermagem

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não participou do processo de avaliação pelos pares. ResumoObjetivo: Desenvolver e analisar as evidências de validade de conteúdo de uma tecnologia educacional do tipo história em quadrinhos (HQ) para pacientes submetidos à Cirurgia de Revascularização do Miocárdio (CRM).Métodos: Estudo de validação realizado em três etapas. A primeira consistiu na avaliação das necessidades de informações dos pacientes submetidos à CRM; a segunda foi o desenvolvimento de um roteiro para a tecnologia educacional do tipo HQ; e a terceira, a análise das evidências de validade de conteúdo desse roteiro, realizada por seis especialistas, sendo considerado válido quando obtido um Índice de Validade de Conteúdo superior a 80%, sendo, posteriormente, elaborada a HQ por um ilustrador.Resultados: Na primeira etapa, 10 pacientes relataram terem necessidades de informações sobre alimentação, consumo de bebidas alcoólicas, controle da ansiedade e do estresse, controle da dor, cuidados com a ferida operatória, tabagismo, atividade física, relação sexual, retorno ao trabalho, liberação para viagens e direção de automóveis. Com base nesses dados, elaborou-se, a partir de revisão de literatura, a história fictícia de um paciente submetido à cirurgia de revascularização do miocárdio, com as respectivas orientações realizadas pela enfermeira. Esse roteiro da HQ foi avaliado pelos especialistas alcançando adequada concordância após a segunda rodada. Após validação, a HQ foi elaborada pelo ilustrador e analisada pelos especialistas.Conclusão: A tecnologia educacional do tipo HQ atingiu adequadas evidências de validade de conteúdo pelos especialistas, podendo ser utilizada como uma das estratégias na orientação da alta hospitalar.

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Prevalence of pharmacological adherence in patients with coronary artery disease and associated factors

Cited by 7 publications

References 30 publications

Drug-Related Problems in Coronary Artery Diseases

Drug-Related Problems in Coronary Artery Diseases

Coronary artery disease incidence, risk factors, awareness, and medication utilization in a 10-year cohort study

Educação em saúde para pacientes submetidos à revascularização miocárdica: validação de história em quadrinhos

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