Obesity, physical activity and prediabetes in adult children of people with diabetes

Compean-Ortiz, Lidia Guadalupe; Trujillo-Olivera, Laura Elena; Valles-Medina, Ana María; Reséndiz-González, Eunice; García-Solano, Beatriz; Pérez, Beatríz Del Angel

doi:10.1590/1518-8345.2102.2981

Cited by 12 publications

(14 citation statements)

References 14 publications

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“…The present findings emphasize the role of obesity as a major risk factor for developing prediabetes in SA. These findings are in accordance with prior reports from SA 31 and worldwide 29,30,32,46 . Lifestyle interventions, including weight reduction, lowered the risk of progression to diabetes mellitus by 58% in the Diabetes Prevention Program 47 .…”

Section: Discussionsupporting

confidence: 93%

Vitamin D levels, prediabetes risk and hemoglobin A1c levels in young non‐diabetic Saudi women

Al-Mohaissen

Lee

Alamri

2020

J of Diabetes Invest

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Aims/Introduction Vitamin D levels are negatively correlated with prediabetes risk and hemoglobin A1c levels in individuals with prediabetes. The data are, however, scarce and inconsistent among different populations. We aimed to assess the association of vitamin D with prediabetes risk and hemoglobin A1c levels in young Saudi women with normoglycemia and prediabetes. Materials and Methods We analyzed the data of individuals without diabetes (without diabetes history and hemoglobin A1c <6.4%) from the Princess Nourah bint Abdulrahman University’s non‐communicable diseases student registry. Demographic data, anthropometric and blood pressure measurements, and hemoglobin A1c and vitamin D results were retrieved and analyzed. Results In total, 345 participants were included in the analysis. The prediabetes status showed no association with vitamin D levels, but it was significantly associated with the participants’ weight and body mass index. Additionally, there was no correlation between the levels of vitamin D and hemoglobin A1c across the whole population, even after correction for body mass index. However, in the body mass index subgroups, when individuals with potentially harmful levels of vitamin D (>125 nmol/L) were excluded, a positive association was detected between vitamin D and hemoglobin A1c levels in the underweight individuals. Hemoglobin A1c values showed a positive correlation only with bodyweight and body mass index. Conclusions Vitamin D levels did not predict prediabetes status and showed no correlation with hemoglobin A1c levels in this population. Vitamin D levels’ effect on the risk of prediabetes might be small compared with other well‐established risk factors, such as obesity.

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Section: Discussionsupporting

confidence: 93%

Vitamin D levels, prediabetes risk and hemoglobin A1c levels in young non‐diabetic Saudi women

Al-Mohaissen

Lee

Alamri

2020

J of Diabetes Invest

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“…Based on our results, the MET score in patients with DM was significantly less than that in the non-DM subjects, and most of them were inactive same the other studies on DM were demonstrated the majority of them has low PA [20]. BMI in the DM and non-DM subjects was the same in this investigation, although other studies showed significantly high BMI in patients with DM [20,21].…”

Section: Discussionsupporting

confidence: 76%

Impact of Physical Activity on the Incidence of Vascular Diseases in Adults with Type 2 Diabetes Mellitus

Pezeshki

Bahramali

Ansari

et al. 2019

GMJ

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Background: Diabetes mellitus (DM) is a common metabolic disease worldwide and has many complications. The vascular events are the major complication of DM that have an important effect on mortality and disability. The physical activity (PA) enhances the vascular function by several pathways. The aim of this study was to evaluation of the relationship between PA and vascular diseases in patients with DM.Materials and Methods: This research was performed as the case-control study that was extracted from a prospective epidemiological research study in Iran (PERSIAN). The patients with type 2 DM more than six months defined as case group and the non-DM subjects in control group with ratio 1:2, and both groups were matched in the term of age and sex. The MET score was used to evaluate the level of PA and blood glucose, lipid profile, body mass index, overweight, dyslipidemia, glomerular filtration rate, myocardial infarction (MI), unstable angina, and stroke.Results: Overall, 1242 patients with DM were extracted, and 2484 non-diabetic subjects were investigated. In the case group, 355(28.6 %) and 887(71.4%) were men and women, respectively, the and 710 (28.6%) men and 1774(71.4%) women in control group. The mean MET score was 30 and 40.97 in the DM and non-DM groups, respectively (P˂0.001). The frequency of MI, stroke, and cardiac ischemia were 44 (3.5%), 37 (3%), and 267 (21.5%), respectively in DM group, and 54 (2.2%), 43 (1.7%), and 389 (15.7%), respectively in non-DM group.Conclusion: The incidence of vascular events associated with PA level in patients with DM and adherence to regular PA reduce the vascular events and DM complications. [GMJ.2019;inpress:e1549]

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“…In this study, we analyzed the data of a high number of adult patients with type 2 DM to evaluate the association between the self-reported MET score and vascular diseases in patients with DM. Based on our results, the MET score in patients with DM was significantly less than that in the non-DM subjects, and most of them were inactive same the other studies on DM were demonstrated the majority of them has low PA [ 20 ]. BMI in the DM and non-DM subjects was the same in this investigation, although other studies showed significantly high BMI in patients with DM [ 20 , 21 ].…”

Section: Discussionsupporting

confidence: 63%

Impact of Physical Activity on the Incidence of Vascular Diseases in Adults with Type 2 Diabetes Mellitus

Pezeshki

Bahramali

Ansari

et al. 2019

GMJ

View full text Add to dashboard Cite

Background: Diabetes mellitus (DM) is a common metabolic disease worldwide and has many complications. Vascular events are the major complication of DM, which have an important effect on mortality and disability. Physical activity (PA) enhances the vascular function by several pathways. The aim of this study was to evaluate the relationship between PA and vascular diseases in patients with DM. Materials and Methods: This study was performed as a case-control study extracted from a prospective epidemiological research study in Iran. Patients with type 2 DM for more than six months as a case group were compared to sex- and age-matched healthy control subjects. The metabolic equivalent of task score was used to evaluate the level of PA and blood glucose, lipid profile, body mass index, overweight, dyslipidemia, glomerular filtration rate, myocardial infarction, unstable angina, and stroke. Results: Overall, 1242 patients with DM were extracted, and 2484 non-DM subjects were investigated. In the case group, 355 (28.6%) and 887 (71.4%) subjects were men and women, respectively, and 710 (28.6%) men and 1774 (71.4%) women were in the control group. The mean metabolic equivalent of task score was 30 and 40.97 in the DM and non-DM groups, respectively (P˂0.001). The frequency of myocardial infarction, stroke, and cardiac ischemia was 44 (3.5%), 37 (3%), and 267 (21.5%) in the DM group, and 54 (2.2%), 43 (1.7%), and 389 (15.7%) in the non-DM group, respectively. Conclusion: The incidence of vascular events associated with PA level in patients with DM and adherence to regular PA reduced vascular events and DM complications. [GMJ.2019;8:e1549]

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Obesity, physical activity and prediabetes in adult children of people with diabetes

Cited by 12 publications

References 14 publications

Vitamin D levels, prediabetes risk and hemoglobin A1c levels in young non‐diabetic Saudi women

Vitamin D levels, prediabetes risk and hemoglobin A1c levels in young non‐diabetic Saudi women

Impact of Physical Activity on the Incidence of Vascular Diseases in Adults with Type 2 Diabetes Mellitus

Impact of Physical Activity on the Incidence of Vascular Diseases in Adults with Type 2 Diabetes Mellitus

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