Consumo De Álcool E a Influência Do Exercício Físico Na Atividade Enzimática De Ratos Wistar

Righi, Thamires; Carvalho, Camilo Amaro de; Ribeiro, Lucas; Cunha, Daise Nunes Queiroz da; Paiva, Ana Carolina Silva; Natali, Antônio José; Pereira, Eveline Torres; Lima, Luciana Moreira

doi:10.1590/1517-869220162201141536

Cited by 3 publications

(3 citation statements)

References 29 publications

(38 reference statements)

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“…One of the potential effects of MC has been the reduction of oxidative stress, reducing the infiltration of inflammatory cells and subsequent fibrosis [27] . This improvement also acts to prevent hepatocyte damage by decreasing the release of this enzyme into the bloodstream [28] .…”

Section: Resultsmentioning

confidence: 99%

Effect of Momordica Charantia on The Prevention of Changes in Serum and Hepatic Metabolism of Animals Fed A High Fat Diet

Franco

Porto

2020

Journal of Gastroenterology and Hepatology Research

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Section: Resultsmentioning

confidence: 99%

Effect of Momordica Charantia on The Prevention of Changes in Serum and Hepatic Metabolism of Animals Fed A High Fat Diet

Franco

Porto

2020

Journal of Gastroenterology and Hepatology Research

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“…Then, analysis of variance (ANOVA) followed by Regarding animal experimentation, the minimum sample size was defined according to an estimated variance previously described in literature [20,[24][25][26].…”

Section: Discussionmentioning

confidence: 99%

“…These data allow us to infer that the association of sedentary lifestyle and alcohol consumption may have promoted a greater release of these enzymes into the plasma. And physical exercise was able to avoid a greater plasma release of ALP in rats that consumed alcohol [26].…”

Section: Morphology Of Hepatocytesmentioning

confidence: 99%

Liver Histology after Chronic Use of Alcohol and Exercise Training in Rats

Lucca¹,

Pereira²,

Righi³

et al. 2018

JPP

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Abstract:Objectives: To investigate the effects of physical training on the liver morphology and morphometry after chronic use of alcohol in rats. Methods: Twenty-four Wistar rats were housed in cages with controlled environment and randomly divided into four groups according to treatment received. In the initial treatment, alcohol was administered to SA (sedentary alcohol) and EA (exercise alcohol) groups. After four weeks, physical training program was held on a treadmill with EA and EC (exercise control) groups. Area, perimeter, maximum and minimum diameter and form factor of nucleus and cytoplasm of hepatocytes were analyzed. Key findings: Micro-vesicular fatty degeneration, predominantly pericentrolobular, of mild to moderate intensity, was found especially in animals treated with alcohol. EC group showed nucleus area greater than the nucleus area of EA and SA groups. The form factor was lower in the EC group than in the EA group. EA group showed maximum cytoplasm diameter is smaller than in SC (sedentary control) group. Conclusions: Physical training for two weeks was not enough to suppress histopathologic changes in the liver caused by chronic use of alcohol in rats. Chronic use of alcohol seems to have minimized the beneficial effect of physical training in the nucleus area of hepatocytes.

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Effects of Resistance Training on Oxidative Stress Markers and Muscle Damage in Spinal Cord Injured Rats

Barros

Aidar

Marçal

et al. 2021

Biology

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Background: Spinal cord injury (SCI) is a condition that affects the central nervous system, is characterized by motor and sensory impairments, and impacts individuals’ lives. The objective of this study was to evaluate the effects of resistance training on oxidative stress and muscle damage in spinal cord injured rats. Methodology: Forty Wistar rats were selected and divided equally into five groups: Healthy Control (CON), Sham (SHAM) SCI Untrained group (SCI-U), SCI Trained group (SCI- T), SCI Active Trained group (SCI- AT). Animals in the trained groups were submitted to an incomplete SCI at T9. Thereafter, they performed a protocol of resistance training for four weeks. Results: Significant differences in muscle damage markers and oxidative stress in the trained groups, mainly in SCI- AT, were found. On the other hand, SCI- U group presented higher levels of oxidative stress and biomarkers of LDH and AST. Conclusion: The results highlight that resistance training promoted a decrease in oxidative stress and a significative response in muscle damage markers.

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Consumo De Álcool E a Influência Do Exercício Físico Na Atividade Enzimática De Ratos Wistar

Cited by 3 publications

References 29 publications

Effect of Momordica Charantia on The Prevention of Changes in Serum and Hepatic Metabolism of Animals Fed A High Fat Diet

Effect of Momordica Charantia on The Prevention of Changes in Serum and Hepatic Metabolism of Animals Fed A High Fat Diet

Liver Histology after Chronic Use of Alcohol and Exercise Training in Rats

Effects of Resistance Training on Oxidative Stress Markers and Muscle Damage in Spinal Cord Injured Rats

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