The aim of this study was to investigate the effect of prophylactic use of nonsteroidal anti-inflammatory drugs (NSAID, i.e. Ibuprofen) on physical performance, vertical jump, muscle biomarkers, liver, kidney, acute pain and hydration status of participants in the 42 km Trail Running Challenge, a long-distance race integrated over mountain routes. The sample consisted of 20 males randomly divided into two groups: a control group (CG) and an experimental group (EG) with 12 completing the race (41.1±8.8 y; 75.7±12.1 kg) and included in the final analysis. The EG were administered an ibuprofen capsule (400 mg) fifteen minutes before the beginning of the race, and again after 5 hours of racing if the route was not yet complete. There were significant time main effects for creatine kinase (CK) (p=0.001; f Cohen=0.25), lactate dehydrogenase (LDH) (p<0.001; f Cohen=2.05), aspartate aminotransferase (AST) (p=0.002; f Cohen=1.53), creatinine (p=0.002; f Cohen=2.24), urea (p=0.001; f Cohen=2.25), heart rate (HR) (p<0.001; f Cohen=4.88) and pain scores (p<0.001; f Cohen=1.93) which all increased during the race. There was a group × time interaction for squat jump (SJ) which significantly decreased in only the CG (p= 0.045; f Cohen=2.17). This may have been related to increased frequency of pain reported after the race in the gastrocnemius of the CG compared to the EG (p<0.05). It was concluded that ibuprofen intake did not reduce muscle damage during the competition but maintained leg muscular power performance (i.e. vertical jump), possibly by reducing gastrocnemius muscle pain.

Background: Spinal cord injury (SCI) is a condition that affects the central nervous system, is characterized by motor and sensory impairments, and impacts individuals’ lives. The objective of this study was to evaluate the effects of resistance training on oxidative stress and muscle damage in spinal cord injured rats. Methodology: Forty Wistar rats were selected and divided equally into five groups: Healthy Control (CON), Sham (SHAM) SCI Untrained group (SCI-U), SCI Trained group (SCI- T), SCI Active Trained group (SCI- AT). Animals in the trained groups were submitted to an incomplete SCI at T9. Thereafter, they performed a protocol of resistance training for four weeks. Results: Significant differences in muscle damage markers and oxidative stress in the trained groups, mainly in SCI- AT, were found. On the other hand, SCI- U group presented higher levels of oxidative stress and biomarkers of LDH and AST. Conclusion: The results highlight that resistance training promoted a decrease in oxidative stress and a significative response in muscle damage markers.

ARTIGO ORIGINAL | ORIGINAL ARTICLE RESUMOO estudo teve por proposta, verificar a correlação entre densidade mineral óssea e nível de atividade física, bem como à ingestão alimentar e parâmetros antropométricos, além de avaliar a densidade mineral óssea (DMO) de mulheres menopausa. Foi feito o exame de densitometria óssea, da região lombar (L1 a L4), colo de fêmur, e fêmur total, como também utilizar o auto-recordatório das atividades do cotidiano de Bouchard; utilizado o registro alimentar de Buker e Stuart, para dosar e quantificar a ingestão diária de cálcio e vitamina D. Os dados foram analisados por meio do teste de Kolmogorov-Smirnov foi considerado um valor padrão de α = 0,05 para comparar as médias das DMO. Constatou-se que cem por cento dos indivíduos avaliados, apresentam um grau de DMO, abaixo da média prevista pela organização mundial de saúde (OMS), estando 14,4% no quadro de osteopenia e 85,6% com osteoporose, com uma menor DMO na região do fêmur (0,721g), e com maior perda entre as mulheres que não fazem atividade física (0,698g). Não houve correlação entre a prática de atividade física e a densidade mineral óssea, porém existe correlação quando associada a padrões antropométricos e ingestão diária de vitamina D.Palavras-chave: Densidade mineral óssea, Atividade Física, Antropométrica. ABSTRACTThis paper aimed to verify the correlation between bone mineral density and the level of physical activity, as well as the food intake and the anthropometric parameters. It intended to analyse the bone mineral density (BMD) of menopausal women through the bone densitometry test (DO) in the lumbar region (L1 to L4), femoral neck and total femur, and also use Bouchard's self-recall of daily activities; employing the food record from Buker and Stuart to dose and quantify the daily intake of calcium and vitamin D. The data were analysed via Kolmogorov-Smirnov's test, and default value of α = 0.05 was set to compare the BMD averages. It was observed that one hundred percent of the assessed individuals had a BMD level below the average fixed by WHO: 14.4% with osteopenia and 85.6% with osteoporosis; a lower BMD in the femoral area (0.721g) and the biggest loss among the sedentary ones (0.698g). It was noticed that there was a correlation between the physical activities and the BMD only when associated with anthropometric standards and the daily ingestion of vitamin D.

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Background: The relationship between training and competition is very important and aims at a more specific and adequate preparation in Jiu-Jitsu. Problem and objective: To evaluate the relationship between training and competition through indications of injury and muscle strength. Methods: The study sample included nine subjects (22.54 ± 2.77 years of age) who were submitted to the following two conditions: 1) training simulation and 2) competition simulation. Results: There were no significant differences in the countermovement jump (CMJ) test. However, 48 hours after training there was an indication of values higher than the post-competition ones. Creatine kinase (CK) indicated significant differences in muscle damage after competition in relation to the other conditions and moments (p <0.01) with a high effect. Lactate dehydrogenase (LDH) showed differences in the moments before, during, and after both competition and training conditions (p <0.05) with a high effect. The power of the upper limbs (PUL) showed a medium correlation at 24h (> 0.55) and 48h (0.47) after the intervention. There was high correlation (> 0.70) for all conditions in the squat jump (SJ). LDH showed a high correlation (> 0.70) at 48 hours. Conclusion: There was a good correlation between training and competition simulation, which tends to indicate that the training model used in the study properly prepare Jiu-Jitsu athletes for the demands of competition. Level of evidence I; High-quality randomized clinical trial with or without a statistically significant difference, but with narrow confidence intervals.