Prebiotic, probiotic and symbiotic as alternative to Antibiotics on the Performance and Immune Response of Broiler Chickens

Abstract

This study aimed to evaluate diets supplemented with prebiotic, probiotic and symbiotic as an alternative to antibiotics on the performance and immune response against the virus of Newcastle disease in broiler chickens. 1,400 one-day old male Cobb 500 chicks were raised until 42 days old in a completely randomized design with 2x2+1 factorial scheme with seven replications. The treatments were: diet without supplementation (base diet -BD), BD + prebiotic, BD + probiotic, BD + symbiotic (prebiotic + probiotic), and BD + antibiotic. The parameters evaluated were performance and antibody serum titers against Newcastle disease. No antibiotic effect was observed on performance. The symbiotic provided better results for weight gain and feed:gain ratio until 21 days old than isolated additives. At 28 days old, the broilers fed diets with prebiotic presented better feed: gain ratio. In the same period (28 d-old), there was an antibody production increase against the Newcastle disease virus in the group supplemented with prebiotic. It can be concluded that the utilization of symbiotic in broiler chickens' diets can substitute performance enhancing antibiotics. The inclusion of prebiotic in the diet improves feed: gain ratio at 1-28 days old. The chickens' immune response increases at 28 days against the Newcastle disease virus in the group supplemented with prebiotic.

Effects of a synbiotic as an antibiotic alternative on behavior, production performance, cecal microbial ecology, and jejunal histomorphology of broiler chickens under heat stress

“…Prebiotics are nondigestible fiber compounds that reduce the pathogenic bacteria through competing for binding sites on the intestinal mucosa and enhance the survival and growth of beneficial microbial species in the gut [21,22]. Several studies have shown a promise outcome to use synbiotics as antibiotic replacements in commercial broiler chickens under thermoneutral temperatures [23][24][25], although some contrasting results have been reported [26,27]. The inconsistent results could be affected by multiple factors such as the birds' age and strain with different survivability, diet quantities and nutrients, and the format of synbiotics and dosage used between the different studies [28].…”

Effect of Adding Cassava Peel and Lactic Acid Bacteria as a Feed Additive to the Weight of Immune Organs of Super Native Chicken

“…The use of synbiotics has the advantage that it can increase the survival of probiotic bacteria due to the specific substrate available for fermentation so that the body gets more perfect benefits (Hamid et al, 2014). In addition, synbiotics are also useful for increasing immunity and production performance in poultry (Murarolli et al, 2014).…”

Arabinoxylo-Oligosaccharides and Inulin Impact Inter-Individual Variation on Microbial Metabolism and Composition, Which Immunomodulates Human Cells

“…Next to improvement of intestinal function itself, dietary nondigestible carbohydrates may also have systemic effects and modulate the immune system in both animals and humans. − These nondigestible carbohydrates might stimulate the immune system via cytokine expression. Little research is conducted on the direct effects on cytokine expression, but many studies have assessed indirect effects through stimulation of beneficial micro-organisms and their metabolism in the gut .…”