Cross-cultural adaptation and validation of Sarcopenia and Quality of Life (SarQoL) in Brazil

Orlandi, Fabiana de Souza; Nunes, Juliana Duarte; Santos, Diana Gabriela Mendes dos; Gratão, Aline Cristina Martins; Zazzetta, Marisa Silvana

doi:10.1590/1516-3180.2021.0968.r1.07042022

Cited by 3 publications

(1 citation statement)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The list of excluded studies and their respective reasons of exclusion is available on our Open Science Framework deposit (https://osf.io/rqhvy/). Therefore, a total of 43 observational studies were included in this systematic review, 42 cross‐sectional studies 5,27–67 and one prospective study 68 for which baseline values of HRQoL for the sarcopenic and non‐sarcopenic groups were used (Figure 1).…”

Section: Resultsmentioning

confidence: 99%

Sarcopenia and health‐related quality of life: A systematic review and meta‐analysis

Beaudart

Demonceau

Reginster

et al. 2023

J cachexia sarcopenia muscle

View full text Add to dashboard Cite

The decrease of physical abilities and functional decline that can be caused by musculoskeletal conditions such as sarcopenia, can lead to higher levels of dependency and disability. Therefore, it may influence patient reported outcome measures (PROM), such as the health‐related quality of life (HRQoL). The purpose of this systematic review and meta‐analysis is to provide a comprehensive overview of the relationship between sarcopenia and HRQoL. Preferred Reporting Items for Systematic Reviews and Meta‐Analyses (PRISMA) were followed throughout the whole process of this work. A protocol was previously published on PROSPERO. The electronic databases MEDLINE, Scopus, Allied and Complementary Medicine (AMED), EMB Review – ACP Journal Club, EBM Review ‐ Cochrane Central of Register of Controlled Trials and APA PsychInfo were searched until October 2022 for observational studies reporting a HRQoL assessment in both sarcopenic and non‐sarcopenic individuals. Study selection and data extraction were carried out by two independent researchers. Meta‐analysis was performed using a random effect model, reporting an overall standardized mean difference (SMD) and its 95% confidence interval (CI) between sarcopenic and non‐sarcopenic individuals. Study quality was measured using the Newcastle‐Ottawa Scale and the strength of evidence was assessed using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) tool. The search strategy identified 3725 references from which 43 observational studies were eligible and included in this meta‐synthesis study. A significantly lower HRQoL was observed for sarcopenic individuals compared with non‐sarcopenic ones (SMD −0.76; 95% CI −0.95; −0.57). Significant heterogeneity was associated with the model (I2 = 93%, Q test P‐value <0.01). Subgroup analysis showed a higher effect size when using the specific questionnaire SarQoL compared with generic questionnaires (SMD −1.09; 95% CI −1.44; −0.74 with the SarQoL versus −0.49; 95% CI −0.63; −0.36 with generic tools; P‐value for interaction <0.01). A greater difference of HRQoL between sarcopenic and non‐sarcopenic was found for individuals residing in care homes compared with community‐dwelling individuals (P‐value for interaction <0.001). No differences were found between age groups, diagnostic techniques, and continents/regions. The level of evidence was rated as moderate using the GRADE assessment. This systematic review and meta‐analysis combining 43 observational studies shows that HRQoL is significantly reduced in sarcopenic patients. The use of disease‐specific HRQoL instruments may better discriminate sarcopenic patients with respect to their quality of life.

show abstract

Section: Resultsmentioning

confidence: 99%

Sarcopenia and health‐related quality of life: A systematic review and meta‐analysis

Beaudart

Demonceau

Reginster

et al. 2023

J cachexia sarcopenia muscle

View full text Add to dashboard Cite

show abstract

Measuring health-related quality of life in sarcopenia: summary of the SarQoL psychometric properties

Beaudart,

Reginster,

Amuthavalli Thiyagarajan

et al. 2023

Aging Clin Exp Res

View full text Add to dashboard Cite

Patient perspectives are now widely recognized as a key element in the evaluation of health interventions. Therefore, the provision of specific and validated Patient Reported Outcome Measures that emphasize the lived experience of patients suffering from specific diseases is very important. In the field of sarcopenia, the only validated specific health-related quality of life (HRQoL) instrument available is the Sarcopenia Quality of Life questionnaire (SarQoL). This self-administrated HRQoL questionnaire, developed in 2015, consists of 55 items arranged into 22 questions and has currently been translated into 35 languages. Nineteen validation studies performed on SarQoL have consensually confirmed the capacity of SarQoL to detect difference in HRQoL between older people with and without sarcopenia, its reliability and its validity. Two further observational studies have also indicated its responsiveness to change. A short form SarQoL, including only 14 items has further been developed and validated to reduce the potential burden of administration. Research on the psychometric properties of SarQoL questionnaire is still encouraged as the responsiveness to change of SarQoL has not yet been measured in the context of interventional studies, as limited prospective data currently exist and as there is still not cut-off score to define a low HRQoL. In addition, SarQoL has mainly been used in community-dwelling older individuals with sarcopenia and would benefit to be studied in other types of populations. This review aims to provide to researchers, clinicians, regulators, pharmaceutical industries and other stakeholders a clear summary of comprehensive evidence on the SarQoL questionnaire published up to January 2023Query.

show abstract

Quality of life in sarcopenia measured with the SarQoL questionnaire: A meta-analysis of individual patient data

Beaudart,

Tilquin,

Abramowicz

et al. 2024

Maturitas

View full text Add to dashboard Cite

Cross-cultural adaptation and validation of Sarcopenia and Quality of Life (SarQoL) in Brazil

Cited by 3 publications

References 20 publications

Sarcopenia and health‐related quality of life: A systematic review and meta‐analysis

Sarcopenia and health‐related quality of life: A systematic review and meta‐analysis

Measuring health-related quality of life in sarcopenia: summary of the SarQoL psychometric properties

Quality of life in sarcopenia measured with the SarQoL questionnaire: A meta-analysis of individual patient data

Contact Info

Product

Resources

About