Carotid body tumor: retrospective analysis on 22 patients

Casarim, André Luís Maion; Tincani, Álfio José; Negro, André Del; Aguiar, Camila Guimarães; FANNI, RENATO VENTURA; Martins, Alessandro F.

doi:10.1590/1516-3180.2014.1323452

Cited by 12 publications

(19 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…A maioria dos paragangliomas não é de origem genética, contudo 10 a 50% destes tumores são hereditários, se manifestando através de um gene autossômico dominante 3,7 . Estudos recentes descreveram uma mutação ao longo das linhas germinativas, o que pode explicar a etiologia, através da identificação de seis genes específicos (RET, VHL, NF1 e subunidades de SDH) .…”

Section: Discussionunclassified

“…Considera-se inoperável quando o tumor envolve toda a carótida interna extracraniana, tornando impossível a anastomose distal com enxerto ou prótese 4,8 . Quanto ao papel da embolização pré-operatória, destaca-se seu uso no caso de grandes tumores, em que ela reduz a perda sanguínea e o tamanho da massa tumoral e melhora os resultados cirúrgicos, porém não se pode descartar o risco de embolia cerebral 7 .…”

Section: Discussionunclassified

“…O tratamento conservador deve ser indicado a pacientes que não são adequados para cirurgia, como os clinicamente instáveis, pacientes extremamente idosos ou com a certeza de ocorrência de acidente vascular encefálico ou ainda se certamente haverá lesão de nervos cranianos que ainda não se instalaram. A radioterapia poderia ser usada, mas isso não é recomendado pela maioria das instituições 7 . Ela pode ser utilizada para tumores inacessíveis, parcialmente ressecados, metastáticos, em casos de recorrência local e nos pacientes em que a cirurgia tem altos índices de morbidade.…”

Section: Discussionunclassified

“…Porém, é necessário lembrar que efeitos colaterais podem ocorrer, como necrose da mandíbula, cérebro e partes moles 8 . Assim, após a realização do tratamento adequado, as taxas de controle dos paragangliomas a longo prazo são de 96% 5,7 .…”

Section: Discussionunclassified

See 3 more Smart Citations

Paraganglioma de corpo carotídeo: relato de caso

Melo

Hamade

Coelho

et al. 2018

Rev. Med. (São Paulo)

View full text Add to dashboard Cite

Os paragangliomas são tumores neuroendócrinos raros com origem em células especializadas derivadas da crista neural. No corpo carotídeo são raros e devem fazer parte do diagnóstico diferencial de tumores da região cervical. Este relato de caso apresenta uma paciente de 24 anos, gênero feminino, com queixa de abaulamento cervical à direita. Foi realizado o tratamento cirúrgico no Hospital Padre Albino. Nesse artigo os autores apresentam um caso de paraganglioma de corpo carotídeo, dando ênfase nos aspectos clínicos, diagnóstico e tratamento.

show abstract

Section: Discussionunclassified

See 2 more Smart Citations

Paraganglioma de corpo carotídeo: relato de caso

Melo

Hamade

Coelho

et al. 2018

Rev. Med. (São Paulo)

View full text Add to dashboard Cite

show abstract

“…Paragangliomas occur along the human body's sympathetic and parasympathetic chains, and this type of neoplasm may develop in various anatomical locations, with the head and neck region being the primary site. Carotid body tumors (CBTs) derive from the neural crest and are a relatively rare type of neck tumor ( 1 ). A CBT located in the upper cervical region is typically considered to be benign and develops slowly ( 2 ); however, CBTs are challenging for surgeons due to the spatial locations and abundant blood supply of this type of neoplasm ( 3 ).…”

Section: Introductionmentioning

confidence: 99%

Diagnosis and treatment of a carotid body tumor: A case report of a rare bilateral tumor

et al. 2017

View full text Add to dashboard Cite

In the present case report, a rare bilateral carotid body tumor (CBT) and the imaging and pathological features of a CBT are described. In the present report, a rare case of bilateral carotid body tumor, which developed in the bifurcation of the common carotid artery, and the clinical manifestations, imaging and pathological features of this CBT are summarized. The imaging cannot validate the diagnosis; however, imaging identified that the tumor exhibited an intact envelope. Immunohistochemical staining revealed that the tumor cells were strongly positive for cluster of differentiation 56, Syn and protein S-100, moderately positive for transcription factor E3, negative for cytokeratin and epithelial membrane antigen, and partial cells were weakly positive for Desmir (<5%). In view of the clinical and pathological features of the carotid body tumor, surgery is hypothesized to be the optimal treatment and may enable the tumor to be resected completely. Refined surgical techniques provide the security of safe resection and decrease the risk of complications occurring.

show abstract

Current trends in carotid body tumors: Comprehensive review

et al. 2022

View full text Add to dashboard Cite

Background: Carotid body tumor (CBT) is a rare neoplasm that has been increasingly studied during the last decades; nevertheless, it continues to be a topic of controversy. This review aims to provide an update on the general features of CBT and particularly review different treatment strategies and primary outcomes. Methods: Data for this literature review were identified by PubMed, Scopus, and Medline. 93 articles from the initial search were included, as well as 28 relevant studies utilizing the snowballing method; totaling 121 articles about CBT. Results: Main features such as anatomy, embryology, genetics, clinical presentation, and diagnosis of CBT are presented, followed by evidence of different treatment strategies such as radiotherapy, preoperative embolization, vascular resection, and vascular reconstruction. Main complications are also discussed. Conclusion:This review summarizes the most critical aspects regarding CBT. Future studies should compare different treatments to attain the best surgical results with lower morbidity rates.

show abstract

Carotid body tumor: retrospective analysis on 22 patients

Cited by 12 publications

References 27 publications

Paraganglioma de corpo carotídeo: relato de caso

Paraganglioma de corpo carotídeo: relato de caso

Diagnosis and treatment of a carotid body tumor: A case report of a rare bilateral tumor

Current trends in carotid body tumors: Comprehensive review

Contact Info

Product

Resources

About