Relationship between blood donors' iron status and their age, body mass index and donation frequency

Moghadam, Ali Malekshahi; Natanzi, Mahboobeh Mehrabani; Djalali, Mahmoud; Saedisomeolia, Ahmad; Javanbakht, Mohammad Hassan; Saboor-Yaraghi, Ali Akbar; Zareei, Mahnaz

doi:10.1590/1516-3180.2013.1316554

Cited by 10 publications

(7 citation statements)

References 22 publications

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“…Several reports showed the iron stored depletion in blood donors. 1,2,4,12 This study also showed the correlation between the frequently time of repeated donations every three months and hematological parameters and also the body iron stored. Because the blood loss that occurs during menstruation by females may affect the body iron, 13,14 only male donors were selected for studying.…”

Section: Discussionsupporting

confidence: 59%

Iron Supplements and Iron Status in Frequent Blood Donors

Sarakul¹

2017

HTIJ

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Background: Iron deficiency anemia is a public health problem worldwide, which can cause by nutrition deficiency, blood loss, and regular blood donation. This study aims to evaluate the hematological parameters and serum ferritin of Thai male blood donors.Methods: Eighty-nine male blood donors were divided into three groups according to their frequency of blood donation: a group of 30 cases for first time donors (group I), a group of 30 cases for donors who have donated 3-6 times (group II), and a group of 29 cases for donors who have donated more than six times (group III). Blood was collected for hematological parameters and for serum ferritin testing by immunological assay.Results: The results showed that the level of serum ferritin tended to decrease with the frequency of blood donation. The level of serum ferritin in blood donors who donated more than six times but did not take a full dose of iron supplements (43.2+25.0µg/L), statisticasignificant decreased when compared with the first donated group (75.4+40.2µg/L) (p=0.03). However, all hematological parameters were not significantly different among these 3 groups. Prevalence of iron depletion without anemia in group II and III were 6% and 3.4%, respectively. Only one donor in group III was iron deficiency anemia. Conclusion:This study shows that blood donation may lead to iron depletion and iron deficiency anemia, especially in more frequent donors. Iron supplements or dietary iron is required after a donation for iron level maintenance and iron deficiency prevention.

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Section: Discussionsupporting

confidence: 59%

Iron Supplements and Iron Status in Frequent Blood Donors

Sarakul¹

2017

HTIJ

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“…Better management approach such as iron supplementation, pro-longing donation intervals and changing from whole blood donation to aphaeresis can reduce donor deferral (Pasricha et In the case of ID, the result in table 2 showed no association between ID and age substantiated by the correlation analysis between age and ferritin concentration (shown in the figure 1), which showed no correlation. However, different outcome was reported in a study conducted in Brazil in which the observed difference only occurred in the blood donors who donated once in the previous year (Moghadam et al 2013). A cross-sectional study showed that age and supplemental iron intake were significantly and positively associated with increased iron stores in women but not in men (Garry et al2000).…”

Section: Discussionmentioning

confidence: 90%

Prevalence of Iron Deficiency, Iron Deficiency Anaemia and General Anaemia in Male Gambian Blood Donors Residing in Greater Banjul Region

Dibbasey

Lawal²,

Umukoro³

et al. 2021

Preprint

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ObjectiveThe objective of this study is to determine the prevalence of iron deficiency (ID) and iron deficiency anaemia (IDA) as well as general anaemia in male blood donors and their association with ageing process.Methodology and ResultsA total of two hundred and one (201) serum samples were analysed for ferritin in male Gambian blood donors. The ferritin measurement was achieved with COBAS® INTEGRA 400 plus. At the same time, haemoglobin values were retrospectively obtained from the archived haematological full blood count result in the GARIS database. IDA was defined as (Haemoglobin <13.0g/dL+ Ferritin<15ng/ml) whilst ID was defined as (Haemoglobin ≥13.0g/dL+ Ferritin<15ng/ml) and general anaemia was defined as haemoglobin <13.0g/dL in males. The prevalence of anaemia (20%, n=41), ID (22%, n=44) and IDA (10%, n=21), were recorded in male donors. The results show no relationship between ferritin and haemoglobin among the blood donors (collection coefficient (r) = 0.04). Besides, no linear association of having anaemia and ID with ageing was reported among the blood donor population.Conclusion and potential application of findingsID and IDA as well as general anaemia are highly prevalent among blood donors in the Gambia. Besides, no predisposition to ID and anaemia was observed in term of age, thus all blood donors from 18-60 should be considered for blood donation without any age preference.

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“…Djalali et al () report on a statistically significant negative correlation of MCHC and the frequency of blood donations ( r = −0·56; P < 0·001). Moghadam et al () also report on a significantly lower MCHC in a population of male donors as compared with non‐donors. Yet, there are studies that failed to demonstrate a decrease in MCHC values relative to the frequency of blood donations (Kwa, ; Okpokam et al , ).…”

Section: Discussionmentioning

confidence: 92%