Diabetes em idosos: uso de medicamentos e risco de interação medicamentosa

Marques

Rev. bras. geriatr. gerontol.

et al. 2017

Objective: To identify the prevalence of diabetes and its relation to associated factors in elderly persons receiving care at a specialist gerontology-geriatric outpatient service. A descriptive cross-sectional study of 301 elderly persons of both genders was performed. Method: The bivariate analysis was performed using the Pearson's Chi-square test for Independence and Fisher's exact test, considering 5% of significance and 95% confidence. A multivariate logistic regression model was adjusted to identify factors that may influence the occurrence of diabetes. Result: There was no statistically significant association between the prevalence of diabetes and socioeconomic and demographic variables, behavioral factors and health conditions. Only the Body Mass Index variable was close to being statistically significant ( p=0.059). Conclusion: The result confirms the need to develop new studies on the subject to consider the particularities and specificities of the elderly population to enable the creation of educational intervention strategies aimed at this group.

Section: Resultscontrasting

confidence: 99%

Factors associated with diabetes among the elderly receiving care at a specialized gerontology-geriatric outpatient clinic

Marques

Rev. bras. geriatr. gerontol.

et al. 2017

“…In this study, in relation to the type of treatment performed for the control of DM2, we highlight the diet and the association of OAD and insulin. Similar data were found in the study with older adults of both genders and with DM2, living in the city of Campinas, where the main strategies used to control DM2 were diet and OAD and insulin (26) . The treatment for DM2 with drugs seems to be more frequently performed by people with the disease, as they do not need to change their life habits.…”

Section: Discussionsupporting

confidence: 87%

Self-care activities, sociodemographic variables, treatment and depressive symptoms among older adults with Diabetes Mellitus

et al. 2019

Objective: to analyze the association between self-care activities of older adults with Type 2 Diabetes Mellitus (DM) and sociodemographic variables, type of treatment and depressive symptoms. Method: inferential and cross-sectional study, with 121 older adults with Type 2 DM in ambulatory care. We used a questionnaire for characterization of sociodemographic and health, questionnaire self-care activities with DM, Mini Mental State Examination and Geriatric Depression Scale. The association of variables was used (Fisher’s exact test) and for comparing the means (Student’s t-test and analysis of variance). Results: The mean age was 68.1 years, the majority were women (57.2%), retired (71.9%) and married (65.3%). The highest averages were for the activities: “to dry the spaces between the toes, after washing them” and smaller averages for “exercise”. Conclusion: In spite of high average for self-care activities, there is a need for enhanced performance and compliance to them.

“…complications and other comorbidities. 27,32 Therefore, in this population, use of five or more medications is frequent and enables drug interactions. 32 Regarding hypothyroidism, it is known that thyroid-related diseases are highly prevalent and occur more frequently among older women.…”

Section: Discussionmentioning

confidence: 99%

“…27,32 Therefore, in this population, use of five or more medications is frequent and enables drug interactions. 32 Regarding hypothyroidism, it is known that thyroid-related diseases are highly prevalent and occur more frequently among older women. 33 The treatment indicated for this condition is based on replacement doses of levothyroxine sodium, a medication for which bioavailability is modified by drug interactions with ferrous sulfate and proton pump inhibitors.…”

Section: Discussionmentioning

confidence: 99%

Potential drug interactions in drug therapy prescribed for older adults at hospital discharge: cross-sectional study

2019

The number of older adults in the world is expanding rapidly as a consequence of increased quality of life and technological advances. 1,2 This demographic transition is increasing the prevalence of chronic-degenerative diseases. One of the consequences is higher consumption of medicines, which implies a great challenge for the healthcare system. 3 Given that use of several drugs is needed to treat the multimorbidity commonly seen in older adults, it can be expected that the prevalence of polypharmacy among older adults and the risk of drug interactions will increase substantially. 4 Drug interactions are a common cause of adverse drug reactions among older adults, and these include arrhythmias, acute kidney injury and increased risk of falls. 5-7 A direct correlation between the number of medications and their interactions and the risk of adverse drug reactions has been shown. 4-7 The reasons for this are multifactorial and particularly include age-related changes in the pharmacodynamics and pharmacokinetics of drugs, reduced renal function and lower hepatic clearance. 6-8 At hospital discharge, older adults generally present changes to their drug therapy, with higher numbers of prescribed medications, which leads to higher frequency of drug interactions. 8 Thus, it is essential to know the frequency of these interactions at hospital discharge among older people and their determinants, in order to promote safer use of drugs among older adults.