Malformações congênitas em municípios de grande utilização de agrotóxicos em Mato Grosso, Brasil

Abstract

Malformações congênitas em municípios de grande utilização de agrotóxicos em Mato Grosso, BrasilCongenital defects in the cities with high use of pesticides in the state of Mato Grosso, Brazil (OR=1,66, IC95% 0,79) e quarto quartil (OR=1,88, IC95% 1,24) do perío-do pós-fecundação e no quarto quartil (OR=2,04, IC95%1,56)

Estudo de base populacional sobre mortalidade infantil

“…Attention is drawn to the prevalence of congenital malformation that remained stable in the Midwest from 1990 to 2007, while decreasing in the South and Southeast and increasing the North and Northeast 4 . Mother's exposure to pesticides widely used in Mato Grosso was associated with the highest occurrence of congenital malformations in the state 23 . On the other hand, congenital malformations were associated with death, a result consistent with that of another study 8 , again in the capital Cuiabá.…”

Análise de indivíduos com leucemia: limitações do sistema de vigilância de câncer

“…The appearance of neoplastic cells will depend on the absorption route and individual susceptibility 16 . Although its use in food production along with fertilizers has increased agricultural productivity, exposure to these substances is associated with environmental and human health issues such as acute poisoning and chronic disorders in the neurological, reproductive and endocrine systems, in addition to the development of cancer in humans 17,18 . In March 2015, the IARC published the monograph, volume 112, in which, after evaluating the carcinogenicity of five active ingredients of pesticides by a team of researchers from 11 countries, including Brazil, they classified herbicide glyphosate and insecticides malathion and diazinon as probable carcinogens for humans (Group 2A) and insecticides tetrachlorvinphos …”

Distribuição espacial do uso de agrotóxicos no Brasil: uma ferramenta para a Vigilância em Saúde

“…Fetal malformation data were acquired from the Live Birth Information System (SINASC), referring to the evidence of congenital anomalies by mother's place of residence. Scientific evidence shows a higher occurrence of malformation in mothers living in rural areas, where mother exposure and mother/father occupational exposure 13,14 to pesticides is found.…”

“…Some pesticides may have effects on human development, such as fetal malformations. Literature indicates that mothers' environmental exposure to pesticides was associated with a higher occurrence of fetal malformation in municipalities with high pesticide use, in all quarters of pregnancy in Mato Grosso 13 . Studies associate father or mother occupational exposure to pesticides with the occurrence of fetal malformation 14,31 .…”