Myelopathy associated with cervical epidural spinal metastasis of follicular-compact thyroid carcinoma in two dogs

Tochetto, Camila; Rosa, Fernanda A.; Santos, Rosmarini Passos dos; Mazzantí, Alexandre; Fighera, Rafael A.; Kommers, Gláucia D.

doi:10.1590/0103-8478cr20141239

Cited by 2 publications

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References 10 publications

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“…Interestingly, three of seven epithelial tumors were thyroid carcinoma with invasion of the spine and intracranial invasion through regions of lysis of the skull and the cranial cervical vertebrae ( Figure 9 ). Previous reports describe epidural metastases of thyroid carcinoma resulting in spinal cord compression, but to the authors' knowledge, this is the first report of direct extension of the primary tumor into the vertebral canal with associated bone lysis and spinal cord compression ( 55 , 56 ). This behavior has also been previously described with carotid body tumors (or paragangliomas) and was also seen in one patient of the present report with a carotid body tumor ( 57 ).…”

Section: Discussionmentioning

confidence: 78%

Magnetic Resonance Imaging Features of Extradural Spinal Neoplasia in 60 Dogs and Seven Cats

2021

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This retrospective study describes the MRI features of extradural spinal neoplasia in 60 dogs and seven cats to identify potential distinguishing features between tumor classes and individual tumor types within each class. In dogs, mesenchymal tumors were most common (48%), with undifferentiated sarcomas being the predominant tumor type. Round cell neoplasms were second most common (35%), with lymphoma and multiple myeloma/plasma cell tumor comprising the majority of cases. Only two benign tumors were identified. In cats, lymphoma was most common (5/7), with one case of mesenchymal neoplasia and one case of metastatic carcinoma. Despite some overlap, certain imaging features were able to help prioritize differential diagnoses. The combined features that predicted round cell neoplasia (84%) included the preservation of vertebral shape, homogeneous contrast enhancement, and lesion centering on bone. The combined features that predicted mesenchymal neoplasia (73%) included altered vertebral shape, heterogeneous contrast enhancement, and lesion centering on paraspinal soft tissues. Round cell neoplasms were more likely to have cortical sparing, preservation of overall shape, lesion centering on bone, small soft tissue tumor size, and homogeneous contrast enhancement. Both epithelial and mesenchymal neoplasms were more likely to have cortical lysis, a cavitary component to the soft tissue mass and medium to large soft tissue mass size. The findings of this study can aid in prioritizing differential diagnoses in cases of extradural spinal neoplasia in cats and dogs, which can impact case management, but tissue sampling remains the gold standard for definitive diagnosis.

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Section: Discussionmentioning

confidence: 78%

Magnetic Resonance Imaging Features of Extradural Spinal Neoplasia in 60 Dogs and Seven Cats

2021

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“…Em dois casos foram observadas metástases epidurais cervicais espinhais. Esses casos foram relatados detalhadamente em outra publicação (Tochetto et al 2015). Metástase pulmonar ocorreu em um caso, assim como metástase em linfonodo cervical.…”

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Neoplasmas da tireoide em cães: 26 casos

et al. 2017

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RESUMO: Foram revisados os protocolos de biópsias e necropsias do Laboratório de Patologia Veterinária da Universidade Federal de Santa Maria (LPV/UFSM) entre 2004 e 2014, e todos os casos de tumores que acometeram a glândula tireoide foram selecionados. A partir disso, foram anotados sexo, idade e raça dos cães afetados. Também foi avaliado o significado clínico dos tumores, presença de aumento de volume cervical, lobos afetados, tamanho dos tumores, presença e localização de metástases e padrão histológico dos neoplasmas. Nos 11 anos que compreenderam este estudo, foram diagnosticados 26 tumores de glândula tireoide (quatro eram provenientes de exames de biópsias e 22 de necropsias), 53,9% dos cães eram fêmeas e 46,1% eram machos; 65,4% eram cães com raça definida. Desses, Boxers foram os mais afetados (15,4% dos casos). Dos 23 protocolos em que a idade foi informada, 60,9% dos cães eram idosos e 39,1% eram adultos. A avaliação dos protocolos permitiu constatar que 38,5% dos animais haviam apresentado aumento de volume cervical no momento do exame clínico. Dos cães necropsiados 13,6% morreram ou foram submetidos à eutanásia em decorrência de complicações causadas por metástases dos tumores de tireoide. Dessa forma, em 86,4% dos cães, os neoplasmas foram considerados achados incidentais de necropsia. Nos quatro casos provenientes de material de biópsia, o desfecho não foi conhecido. Em nenhum cão os tumores causaram síndrome clínica devido à hipo ou hiperfunção da tireoide. Em 24 protocolos havia informação sobre os lobos afetados e 75% dos cães tiveram acometimento unilateral da glândula. Os diagnósticos histológicos dos tumores permitiram constatar que 16 (61,5%) neoplasmas eram carcinomas de células foliculares (nesses casos, o padrão folicular-compacto foi o mais frequente [43,75%]), seis (23,1%) eram adenomas de células foliculares, dois (7,7%) eram carcinossarcomas e dois (7,7%) eram tumores de células C (adenoma e carcinoma).

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Myelopathy associated with cervical epidural spinal metastasis of follicular-compact thyroid carcinoma in two dogs

Abstract: Myelopathy associated with cervical epidural spinal metastasis of follicular-compact thyroid carcinoma in two dogs.Ciência Rural, v.45, n.8, ago, 2015.

Cited by 2 publications

References 10 publications

Magnetic Resonance Imaging Features of Extradural Spinal Neoplasia in 60 Dogs and Seven Cats

Magnetic Resonance Imaging Features of Extradural Spinal Neoplasia in 60 Dogs and Seven Cats

Neoplasmas da tireoide em cães: 26 casos

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