Monensina sódica sobre vacas em fase inicial de lactação: produção de leite e peso vivo

Possatti, Carolina D'ávila; Haddade, Ismail Ramalho; Kill, João Luís; Haese, Douglas; Neto, Alberto Chambela; Simon, Carla da Penha; Rocha, Isabel Araújo; Nascimento, João Vitor Miranda do; Garcia, Willian Alves

doi:10.1590/0103-8478cr20131684

Cited by 3 publications

(3 citation statements)

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“…Monensin is known to promote rumen microenvironment change in cattle rumen, modifying the proportion of volatile fatty acids (PERRY et al, 1976). Dairy cows fed with sodium monensin supplemented diets have contents of total solids in milk increased; thus, supplementation of early lactating cow diets, with such component can be inherently associated with milk production (POSSATTI, et al, 2015). Moreover, monensin has shown to increase permeability of Na + , K + , and H + ions to muscle cell cytosol with excitatory effects due to depolarization of presynaptic nerve endings (SHERIDAN, 1996) and Ca ++ influxes, leading to cardiac and skeletal degeneration and necrosis (GUPTA, 2012).…”

Section: Introductionmentioning

confidence: 99%

Outbreak of monensin poisoning in cattle due to supplementation error

et al. 2020

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Iatrogenic intoxications occur in domestic animals. Mortality was observed in a group of calves, reaching 20 deaths until the day of the technical visit, with or without sudden clinical signs, on a farm in the city of Pires do Rio, State of Goiás, Brazil. Deaths after the visit were not accounted systematically. Clinical signs included muscle weakness, ataxia, recumbency, bilateral jugular distention, and death. Suspected diagnosis of poisoning by ionophore antibiotics was made based on clinical and laboratory findings from nine animals, which included high plasma CK and LDH levels, as well as on anatomopathological findings of a recently dead calf, which showed myocardial and skeletal muscle degeneration and necrosis. Monensin overdose (25.5 µg/kg in skeletal muscle and 209.4 µg/kg in the liver) was detected by liquid-chromatography and mass-spectrophotometry analysis, contributing to the confirmation of ionophore poisoning diagnosis.

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Section: Introductionmentioning

confidence: 99%

Outbreak of monensin poisoning in cattle due to supplementation error

et al. 2020

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“…Monensin has a limited effect on DMI (Ipharraguerre and Clark 2003;Possatti et al, 2015). Since it has the potential to increase the supply of gluconeogenic precursors, monensin administration might increase hepatic synthesis of glucose, thereby improving the energy balance in dairy cows (Ipharraguerre and Clark, 2003).…”

Section: Discussionmentioning

confidence: 99%

“…The monensin doses in those studies were different; therefore, we cannot claim that absence of effect in the present study was only a function of monensin amount. Indeed, the effects of monensin intake have shown to be less significant in cows fed roughage (Possatti et al, 2015).…”

Section: Discussionmentioning

confidence: 99%

Pelleting and sodium monensin increase milk CLA concentration from dairy cows fed flaxseed

Romero

Marchi

Alcalde

et al. 2018

Rev Colomb Cienc Pecu

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El peletizado y la monensina sódica incrementan la concentración de CLA en leche de vacas suplementadas con linaza Peletização e monensina sódica aumentam a concentração de CLA no leite de vacas alimentadas com linhaçaAbstract Background: Demand for naturally enriched foods is increasing worldwide. Animal nutrition allows incorporating nutraceutical molecules into milk. These molecules are intended for improving human health. Objective: To evaluate the effects of pelleting and monensin addition to the diet on intake, digestibility of dry matter (DM) and nutrients, milk yield and composition, and fatty acids (FA) profile in cows kept on pasture and supplemented with concentrate containing ground flaxseed (GF). Methods: Four Holstein cows were assigned to the following treatments: 1) concentrate with GF; 2) GF + 32.93 mg/Kg monensin (GFM); 3) GF pelleted (GFP); 4) GF pelleted + 32.93 mg/Kg monensin (FMP). Results: Treatments did not show effects on digestibility of dry matter (DM) and nutrients or feed intake, with the exception of ether extract intake, which was reduced by 28% with pelleting. Addition of monensin increased the conjugated linoleic acid (CLA) concentration by 47%. Pelleting increased the concentrations of CLA (70%), polyunsaturated FA (PUFA; 25%), Rev Colomb Cienc Pecu 2018; 31(2):110-119Vieira Romero J et al. Pelleting and monensin increase milk CLA and monounsaturated FA (MUFA; 16%), and reduced the concentrations of steric acid (C18) in 19% and total saturated FA (SFA; 14%). Conclusion: Pelleting and monensin does not alter feed intake and digestibility of DM and nutrients. Pelleting of concentrate feed containing flaxseed improves milk FA quality. ResumenAntecedentes: La demanda por alimentos naturalmente enriquecidos se ha venido incrementado en todo el mundo. A través de la nutrición animal es posible incorporar moléculas nutracéuticas en la leche. El uso de estas moléculas pretende mejorar la salud humana. Objetivo: Evaluar los efectos de la peletización y la monensina sobre la ingesta, digestibilidad de la materia seca (DM) y nutrientes, producción de leche, composición y perfil de ácidos grasos (FA) en leche de vacas en pastoreo que consumen alimento concentrado formulado con linaza molida (GF). Métodos: Cuatro vacas Holstein fueron distribuidas en los siguientes tratamientos: 1) ración conteniendo GF; 2) GF + 32,93 mg/Kg de monensina (GFM); 3) GF en pellets (GFP); 4) GF en pellets + 32,93 mg/Kg de monensina (FMP). Resultados: Los tratamientos no mostraron efectos en el consumo y digestibilidad de la DM y nutrientes, excepto por el consumo de extracto etéreo, con una reducción del 28% en las raciones peletizadas. La monensina incrementó la concentración de ácido linoleico conjugado (CLA) en 47%. La peletización aumentó el contenido de CLA (70%), FA poliinsaturados (PUFA; 25%) y FA monoinsaturados (16%); y redujo las concentraciones de C18 en 19%, y FA saturados total en 14%. Conclusión: El peletizado y la monensina no alteran la ingesta de alimento ni la digestibilidad de la DM y nutrientes...

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Effects of increasing monensin doses on performance of mid-lactating Holstein cows

Santos

Araújo

Venturelli

et al. 2019

Journal of Applied Animal Research

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The objective of this study was to determine the effect of increasing monensin doses on intake, nutrient digestion, ruminal fermentation, nitrogen balance, blood metabolites, milk yield and composition of lactating dairy cows. Twelve Holstein cows (135 ± DIM; 580 ± kg of BW) were assigned to three 4 × 4 Latin square design, with 21-d periods. Cows were randomly assigned within each square to receive one of the following treatments: Control (C): 0 mg kg −1 DM of monensin; Monensin 12 (M12): 12 mg kg −1 DM of monensin; Monensin 24 (M24): 24 mg kg −1 DM of monensin and Monensin 48 (M48): 48 mg kg −1 DM of monensin. Monensin had quadratic effect on intake of dry matter. Apparent total-tract digestibility of DM were similar between treatments; however, digestibility of CP increased. Monensin had no effect on ruminal pH, NH 3 concentration, but propionate increased by monensin. Blood urea nitrogen was increased linearly by monensin. There was a quadratic effect of monensin on N intake. Monensin had a quadratic effect on milk yield, whereas 3.5% FCM was decreased linearly. These results suggest that monensin improves performance of mid-lactating dairy cows fed corn silage-based diet, and monensin can be added up to 24 mg/kg of DM diets. ARTICLE HISTORY

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Monensina sódica sobre vacas em fase inicial de lactação: produção de leite e peso vivo

Abstract: RESUMO Avaliou-se o efeito do fornecimento de monensina sódica no desempenho de vacas leiteiras em fase inicial de lactação, cuja alimentação, em sua dieta total no cocho, compôs-

Cited by 3 publications

References 8 publications

Outbreak of monensin poisoning in cattle due to supplementation error

Outbreak of monensin poisoning in cattle due to supplementation error

Pelleting and sodium monensin increase milk CLA concentration from dairy cows fed flaxseed

Effects of increasing monensin doses on performance of mid-lactating Holstein cows

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