Similar Sealability Between Bioceramic Putty Ready-To-Use Repair Cement and White MTA

Abstract

This study was designed to assess the ability to prevent glucose penetration of a bioceramic putty ready-to-use repair cement comparing to white mineral trioxide aggregate (WMTA). After root canal instrumentation, the apical 3 mm of maxillary incisors were resected and root-end cavities with depth of 3 mm were prepared with ultrasound and filled with the tested materials (15 roots per group). All roots were mounted in a double chamber system to assess glucose penetration using 15 psi pressure application. After 1 h, glucose concentrations in the lower chamber were measured following an enzymatic reaction. Four roots were used as controls. The Mann-Whitney test verified differences in glucose leakage between groups and the Tukey's test was used for multiple comparisons. Significance level was set at 5%. There was no significant difference in glucose leakage between iRoot BP Plus and White MTA groups. iRoot BP Plus had a similar ability to that of white MTA in preventing glucose leakage as a root-end filling material.

In vitro and in vivo evaluation of a nanoparticulate bioceramic paste for dental pulp repair

“…Nanosized biomaterials play an important role in tissue repair and regeneration due to their unique nanostructure and biological functions. Recently, as a revolutionary ready-to-use nanoparticulate bioceramic with the advantage of handling ease, iRoot BP Plus has been developed for potential dental surgery applications [13,15]. Our results first showed that nanoparticulate iRoot BP Plus possessed excellent apatite-forming ability, promoted in vitro recruitment of DPSCs, and facilitated the dentin bridge formation in a pulp repair model in vivo.…”

“…iRoot BP Plus is a novel ready-to-use laboratory-synthesized calcium silicate-based nanoparticulate bioceramic paste, which has been claimed to offer revolutionary improved performance compared with current hand-mixed MTA. iRoot BP Plus is an insoluble, radiopaque, aluminium-free and zirconium oxide-incorporated material developed for potential dental surgery applications [13,14]. Because of its nanomodified nature and ease of handling, iRoot BP Plus has been speculated to be a promising MTA alternative.…”

“…However, the underlying mechanism of bioceramic-mediated dental pulp repair is far from being completely understood [17,19]. Concerning iRoot BP Plus [13,15], no studies have yet demonstrated the bioactivity of this nanoparticulate bioceramic and its biocompatibility with DPSCs, or its direct effects on the pulp tissues of a living organism. Therefore, the aim of the present study was to characterize and determine the apatite-forming ability of iRoot BP Plus, and to investigate its effects on the in vitro recruitment (adhesion, migration and attachment) of DPSCs, as well as its capacity to induce dentin bridge formation in an in vivo model for pulp repair.…”

Importance and methodologies of endodontic microleakage studies: A systematic review

“…The maxillary segment of the syringe containing the glucose solution is connected to a pressure source to create a headspace pressure of 103 kPa per 60 minutes (76). Souza et al (79) amplified the pressure in the maxillary chamber of the GLM system to accelerate glucose leakage from weeks to hours in order to decrease the risk of bacterial growth and long-term water evaporation, while maintaining the capacity to detect the leaking samples.…”

Push-out Bond Strength of Root-end Filling Materials

“…MTA-based root-end filling materials have been developed (4,5). An experimental sealer (MTA Sealer) was developed based on white Portland cement, zirconium oxide (radiopaque filler), calcium chloride (additive) and resin to be used as a root canal filling material (5).…”