Analysis of cardiac exams: electrocardiogram and echocardiogram use In Duchenne muscular dystrophies

Abstract

Introduction Duchenne Muscular Dystrophies (DMD) is a genetic muscle disorder that causes degeneration and atrophy of skeletal muscle and heart. Objective The aim of this survey is accomplish an evaluation electrocardiographic and echocardiography in the patients bearers of Duchene Muscular Dystrophies (DMD), to observe which alterations, which the degree of cardiac compromising these patient present and the effectiveness of these exams in the evaluation cardiologic. Methods Nine patients of the sex male bearers of DMD, with medium age of 14.12 ± 4.19 years, varying of 7 to 23 years were appraised. All were submitted to the evaluation physiotherapy and the cardiologic: electrocardiogram and echocardiogram. Results The experimental conditions of the present survey we propitiate the observation of the alterations echocardiography, as well as: significant increase in the diastolic diameter of the left ventricular (LV), increase in the systolic diameter of the left atrium (LA), and significant decrease of the ejection fraction of the LV, characterizing global systolic function reduced, and of the alterations electrocardiographic suggested possible overload of RV, septum hypertrophy, blockade of left previous fascicle and overload of atrium left. Compatible alterations of hypertrophy left ventricular were not observed. Conclusion The evidences corroborate with the data described in the literature in the characterization of an important heart compromising that these patient present, like this the evaluation cardiologic, through the complemented exams of the echocardiography and electrocardiography provide important information for the prognostic, the accompaniment, and the treatment of patient bearers of DMD.

Autonomic modulation at rest and in response to postural change in adolescents with Duchenne muscular dystrophy: a cross-sectional study

“…Reduced parasympathetic and global modulation in individuals with DMD had already been reported in the literature 3,5 but the way that autonomic function changes in patients with Duchenne muscular dystrophy (DMD. Autonomic alterations may be considered to be a predictor of cardiovascular and metabolic health in the overall population 8,21 .…”

“…Duchenne muscular dystrophy (DMD) is a progressive neuromuscular disease affecting approximately 1 in 3500 newborn males 1,2 . DMD affects not only the neuromuscular systems but also the cardiac, respiratory and autonomic system [3][4][5][6] . Progressive cardiac disorders are considered to be one of the major causes of premature death among individuals with DMD.…”