Exposição ambiental e ocupacional a agrotóxicos e o linfoma não Hodgkin

Costa, Vlaudia Maria Assis; Mello, Márcia de Campos de Sarpa; Friedrich, Karen

doi:10.1590/0103-1104201711205

Cited by 28 publications

(29 citation statements)

References 15 publications

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“…However, seven out of twelve studies in rats found growth of malignant tumor (25) . An integrative review about pesticides and non-Hodgkin's lymphoma was found association between glyphosate and this type of cancer (26) .…”

Section: Discussionmentioning

confidence: 99%

Epidemiological profile of farmworkers from the state of Rio de Janeiro

et al. 2019

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Objective: to describe the epidemiological profile of farmworkers exposed to pesticides in the city of Casimiro de Abreu, Rio de Janeiro State. Method: cross-sectional study, conducted through a questionnaire. The collected data were typed in spreadsheet and processed in the R software. Results: the predominance of female participants, between 40 and 60 years old, married, with some elementary education was observed. Furthermore, the family labor and the production for their own consumption and trade prevail. Herbicide is the most widely used pesticide. Most informants present poisoning symptoms, as they do not use Personal Protective Equipment nor sunscreen. Breast cancer is the most frequent in families; among the participants, 31% had hypertension and 6.4% diabetes. Conclusion: a population vulnerable to environmental and occupational risks, specially the middle-aged group and women, sets up a profile marked by regional differences.

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Section: Discussionmentioning

confidence: 99%

Epidemiological profile of farmworkers from the state of Rio de Janeiro

et al. 2019

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“…A exposição aos agrotóxicos pode também causar alterações celulares, sendo que essas alterações consequentemente podem estar associadas a diferentes tipos de cânceres, como por exemplo: câncer no cérebro, linfoma não-Hodgki, melanoma cutâneo, câncer no sistema digestivo, sistemas genitais masculino e feminino, sistema urinário, sistema respiratório (Wilhelm et al, 2015, Da Silva et al, 2012, Miranda et al, 2014, Buccolini et al, 2013, Costa et al, 2017, Fortes et al, 2016, Segatto et al, 2015& Da Silva et al, 2016.…”

Section: Uso Dos Agrotóxicosunclassified

Avaliação toxicológica: alterações em biomarcadores desencadeadas por exposição de trabalhadores rurais a agrotóxicos

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Souza²,

Costa

et al. 2021

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Os agrotóxicos ou pesticidas são considerados substâncias quimícas que agem no meio ambiente, no sentido de controlar diferentes elementos que prejudicam o cultivo das lavouras ou pastagens, geralmente, sendo utilizados por trabalhadores ocupacionais a nível rural no intuito de maior produção e erradicação de doenças e pragas exitentes. Muitos trabalhadores não sabem lidar corretamente com a aplicação, compra, diluição e descarte dos agroquímicos. Dessa maneira, esta pesquisa tem como objetivo discutir as principais alterações em biomarcadores desencadeadas por exposição de trabalhadores rurais a agrotóxicos. Como metodologia o presente estudo trata-se de revisão narrativa, realizada entre os meses de agosto e dezembro de 2020. O levantamento de dados não se pautou para restrição do ano de publicação dos estudos encontrados. As bases de dados utilizadas foram: National Center for Biotechnology Information (PUBMED); Scientific Electronic Library Online (SCIELO); Literatura Latino- Americana e do Caribe em Ciências da Saúde (LILACS); sites confiáveis; livros. A presente pesquisa mostra que o monitoramento de biomarcadores de exposição a agrotóxicos pode ser útil para verificar o surgimento de disfunções fisiológicas em populações expostas. Ressalta-se que os biomarcadores mais utilizados para a avaliação dos trabalhadores expostos aos agrotóxicos seriam as enzimas acetilcolinesterase eritrocitária (AChE) e butirilcolinesterase (BuChE), assim com o processo de exposição a agrotóxicos desencadea uma série de reações fisiológicas a nível nervoso, diminuindo, principalmente, a ação da enzima acetilcolinesterase, essa que por sua vez é responsável pela quebra do excesso da acetilcolina.

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“…They are irreversible inhibitors of cholinesterase, but do not accumulate in the organism and are easily degraded. Intoxication can cause bradycardia, arterial hypertension, diarrhea, muscular fasciculation, respiratory insufficiency, convulsions, miosis, drooling, and there is always a great risk of death (Hungaro et al, 2015) and development of oncological diseases (Costa et al, 2017). c) Carbamates: these are also inhibitors of cholinesterases; however, this inhibition is reversible due to a weak bond with the enzyme (Hungaro et al, 2015).…”

Section: Introductionmentioning

confidence: 99%

“…c) Carbamates: these are also inhibitors of cholinesterases; however, this inhibition is reversible due to a weak bond with the enzyme (Hungaro et al, 2015). Another aggravating factor is their relationship with congenital deformities, such as spina bifida (Dutra and Ferreira, 2017) and the development of non-Hodgkin's lymphoma (Costa et al, 2017). This class of agrochemicals has the advantage of being rapidly decomposed in aquatic environments (Nascimento and Melnyk, 2016).…”

Section: Introductionmentioning

confidence: 99%

Exposure to agricultural pesticides and use of personal protection equipment by small-scale farmers in a municipality of Minas Gerais, Brazil

et al. 2020

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The use of agricultural pesticides in Brazil has significantly increased during recent decades, especially due to the competition between the internal Brazilian market and that for exports. Pesticides are among the most important risk factors for the health of the general population, especially workers, and the environment, resulting in a scenario of increased public spending on health and social damage due to pollution by such chemicals, with emphasis on organophosphates and carbamates. When these substances are managed incorrectly, such as when personal protection equipment (PPE) is not used, or when they are inadequately discarded without adhering to sanitary disposal guidelines, they can cause pollution and short- and long-term damage to health. This paper therefore surveys the knowledge base of small-scale farmers with respect to exposure to agrochemicals and the importance of use of PPEs. This qualitative and transversal study relied upon the voluntary participation of 64 residents of a rural area. The study was initiated after having received approval of the Committee for Ethics in Research, and after the participants signed an informed consent form. A questionnaire was given to the participants which used multiple choice and open-ended questions. All the participants stated that they use fertilizers and other agrochemicals, and that they do not use or only sporadically use PPEs. All the participants related that they have not had access to specialized technical assistance to help with proper use of agrochemical products, and that they store these products inadequately in their house or in other inappropriate places. These small-scale farmers do not use PPEs and underestimate the damage to their health and that of their family that can be caused by improper use of agrochemicals, and also demonstrate a lack of technical knowledge with respect to adequate management of these products.

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Exposição ambiental e ocupacional a agrotóxicos e o linfoma não Hodgkin

Cited by 28 publications

References 15 publications

Epidemiological profile of farmworkers from the state of Rio de Janeiro

Epidemiological profile of farmworkers from the state of Rio de Janeiro

Avaliação toxicológica: alterações em biomarcadores desencadeadas por exposição de trabalhadores rurais a agrotóxicos

Exposure to agricultural pesticides and use of personal protection equipment by small-scale farmers in a municipality of Minas Gerais, Brazil

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