2014
DOI: 10.1590/0102-695x20142413347
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Phytochemical study and antinociceptive effect of the hexanic extract of leaves from Combretum duarteanum and friedelin, a triterpene isolated from the hexanic extract, in orofacial nociceptive protocols

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Cited by 18 publications
(9 citation statements)
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“…In addition, it has been suggested that the association of natural products with preventive care can reduce the high incidence of diseases that affect the dental element as the periodontal disease (Juiz et al, 2010;Siqueira et al, 2010;Guimarães et al, 2013). Recently, our group has developing study about the pharmacological use of natural products, as medicinal plants, to treat orofacial disroders Bonjardim et al, 2011;Siqueira-Lima et al, 2014;Quintans et al, 2014).…”
Section: Introductionmentioning
confidence: 99%
“…In addition, it has been suggested that the association of natural products with preventive care can reduce the high incidence of diseases that affect the dental element as the periodontal disease (Juiz et al, 2010;Siqueira et al, 2010;Guimarães et al, 2013). Recently, our group has developing study about the pharmacological use of natural products, as medicinal plants, to treat orofacial disroders Bonjardim et al, 2011;Siqueira-Lima et al, 2014;Quintans et al, 2014).…”
Section: Introductionmentioning
confidence: 99%
“…This compound is not only present in G.dulcis plants but is widely distributed in various other plants. [38][39][40] Compound 68 was found in the stems and leaves of G. dulcis. 29,41 Friedelin has an antibacterial effect on Gram-positive bacteria.…”
Section: E) the Triterpenoidmentioning
confidence: 99%
“…Na medicina popular C. duarteanum é utilizada como expectorante (ALBUQUERQUE et al, 2007) e no tratamento de dor e como sedativo (GOUVEIA et al, 2011). Estudos relatam que o extrato etanólico das folhas desta espécie C. duarteanum possui atividade antinociceptiva (QUINTANS et al, 2014), antioxidante, anti-inflamatória (GOUVEIA et al, 2011), gastroprotetora (LIMA et al, 2013) e antimicrobiana (NASCIMENTO; CHIAPPETA; LIMA, 1990) e a fração hexânica do extrato etanólico das folhas possui atividade antinociceptiva (QUINTANS et al, 2014) e gastroprotetora (LIMA et al, 2013).…”
Section: Introductionunclassified