Liver transplantation in Brazil

Pacheco, Lucio

doi:10.1590/0100-69912016004014

Cited by 6 publications

(2 citation statements)

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“…The high number of deaths of patients who are on the waitlist in Brazil is 2 , in some parts, a reflex of the low rates of organ donation, around 16.6 per million population (pmp) 4 , while in the USA and other european countries the rates go up to 25 and 30 pmp, respectively 20 . Clearly, that increases the time and mortality of patients on the waitlist, and because of that, surgeons end up using expanded criteria livers 7 .…”

Section: Discussionmentioning

confidence: 99%

Bar, Soft and Dri Post-Hepatic Transplantation: What Is the Best for Survival Analysis?

Torterolli

Watanabe

Tabushi

et al. 2021

ABCD, arq. bras. cir. dig.

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Background: Liver transplantation is the treatment of choice for patients with terminal liver disease. The Balance of Risk Score (BAR), Survival Outcomes Following Liver Transplantation (SOFT) and Donor Risk Index (DRI) scores are predictive systems for post-transplant survival. Aim: To evaluate the most accurate score and the best cutoff point for each predictor in the brazilian population. Method: Retrospective cross-sectional study of 177 patients. Data on the recipient, donor and transplant were analyzed and the prognostic scores BAR, SOFT and DRI were calculated for each transplant. To determine the BAR and SOFT cutoff points associated with death in three months, ROC curves were adjusted. Results: The best cutoff point for BAR was 9 points with an area under the ROC curve=0.69 and for SOFT it was 12 points with an area under the ROC curve=0.73. The DRI score did not discriminate survival (p = 0.139). Conclusion: The SOFT score proved to be better than BAR for survival analysis post-hepatic transplantation and the DRI was not effective.

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Section: Discussionmentioning

confidence: 99%

Bar, Soft and Dri Post-Hepatic Transplantation: What Is the Best for Survival Analysis?

Torterolli

Watanabe

Tabushi

et al. 2021

ABCD, arq. bras. cir. dig.

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“…The first liver transplant in Brazil took place in São Paulo in 1968, and during the 1970s, the development of immunosuppression was observed. Thus, in 1984, liver transplantation left the experimental field and began to be considered a medical therapy 2 .…”

Section: Introductionmentioning

confidence: 99%

Economic Impact of Pharmaceutical Recommendations Carried Out in a Liver Transplant Unit of a University Hospital

Nascimento,

Oliveira,

Neto

et al. 2024

BJT

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Introduction: Advances in medicine have provided the possibility of organs and tissues transplantation for therapeutic purposes. Transplant patients, in addition to immunosuppressive therapy, mostly undergo treatment for other comorbidities, and this polypharmacy makes the role of the pharmacist extremely important to ensure patient safety and adherence. Through pharmaceutical recommendations, the professional can reduce morbidity and mortality and thus reduce healthcare costs. Methods: This is an observational, retrospective descriptive study, carried out from January 2021 to December 2022, aiming to analyze the economic impact of pharmaceutical recommendations made in a liver transplant unit of an university hospital. Data collection took place from May to August 2023 through the institution’s clinical pharmacy database. The economic impact was classified as effectiveness increased (EI), cost reduction (RC), and avoided risk (AR) calculated through a methodology developed and adapted to the study’s reality. Medication acquisition costs were verified through the hospital’s own system, and the values were adjusted according to inflation in June 2023. Results: A total of363 pharmaceutical recommendations (PR) were conducted, of which the EI represented 64% (n = 231), followed by RC (20%, n = 72) and risk avoided (16%, n = 60). The total resulting value corrected by the Índice Nacional de Preços ao Consumidor Amplo (IPCA) was R$ 179,223.31, with the AE at R$ 140,414.04 and the RC at R$ 38,809.27. Conclusion: The importance of the clinical pharmacist in the multidisciplinary team is evident through the improvement of patient monitoring and health condition management. Through this study, we can perceive that the PR presented had a considerable financial impact, and, through the optimization of pharmacotherapy for transplant patients, an increase in therapeutic EI was obtained. The importance of developing further studies showing the impact of the quality of care provided by the pharmacy’s performance is clear, to further highlight the importance of this field for healthcare assistance.

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Pediatric Liver Transplantation in South America: Incidence and Indications

Porta¹

2021

Pediatric Liver Transplantation

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Liver transplantation in Brazil

Cited by 6 publications

References 0 publications

Bar, Soft and Dri Post-Hepatic Transplantation: What Is the Best for Survival Analysis?

Bar, Soft and Dri Post-Hepatic Transplantation: What Is the Best for Survival Analysis?

Economic Impact of Pharmaceutical Recommendations Carried Out in a Liver Transplant Unit of a University Hospital

Pediatric Liver Transplantation in South America: Incidence and Indications

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