PET/CT in the evaluation of pulmonary solitary nodule

Barbosa, Felipe de Galiza

doi:10.1590/0100-3984.2016.49.2e4

Cited by 2 publications

(1 citation statement)

References 7 publications

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“…Its occurrence rate in peripheral lung cancer was approximately 65.0% ( 19 ). Expanded bronchioles can form an air bronchogram, and the effects of tumors on bronchi include the truncation of the bronchus by a tumor edge, a bronchus being contained by the tumor, and the lumen of the bronchus being pressed and translocated with thickening of the smooth mucous membrane layer of the bronchial wall ( 20 ). Other changes include the transmigration stenosis of the lumen and irregular stenosis.…”

Section: Discussionmentioning

confidence: 99%

Differential diagnosis of solitary pulmonary nodules with dual-source spiral computed tomography

Shi

Wang

2016

Experimental and Therapeutic Medicine

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The aim of the present study was to analyze the value of applying dual-source 64-layer spiral computed tomography (CT) in the differential diagnosis of solitary pulmonary nodules (SPNs). Mediastinal windows from 45 cases were selected to study SPNs (maximum diameter, ≤3 cm), and the pathological nature of lesions was determined by clinical and pathological diagnosis. Conventional 64-layer spiral CT scanning, local enhancement and 3D recombination technologies were used to determine the occurrence rate, lesion diameter, degree of enhancement, lobular sign, spicule sign, pleural indentation sign, vessel convergence sign and bronchus sign. The final diagnoses indicated 34 cases of malignant SPNs (75.6%) and 11 benign cases (24.4%). When the nodule diameter in the malignant group was compared with that of the benign group, the difference was not statistically significant (P>0.05). Nodules in the malignant group showed inhomogeneous enhancement while nodules in the benign group showed homogeneous enhancement. The enhanced CT values in the malignant group were higher than those in the benign group, and the difference was statistically significant (P<0.05). The proportion of nodules with lobular sign in the malignant group was significantly higher than that in the benign group (P<0.05). The proportion of nodules with calcification, vessel convergence sign and bronchus sign in the malignant group were significantly higher than those in the benign group, and the differences were statistically significant (P<0.05). A comparison of vacuole sign, pleural indentation sign, spiculate protuberance and fat occurrence between the two groups yielded no statistically significant differences (P>0.05). The sensitivity of CT enhancement was 85.6%, specificity was 79.6%, positive predicated value was 92.3%, and the negative predicted value was 85.2%. In conclusion, SPNs diagnosed by CT enhancement manifested with enhancement degree, lobular sign, calcification, vessel convergence sign and bronchus sign with high diagnostic accuracy.

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Section: Discussionmentioning

confidence: 99%

Differential diagnosis of solitary pulmonary nodules with dual-source spiral computed tomography

Shi

Wang

2016

Experimental and Therapeutic Medicine

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Pitfalls and artifacts in the interpretation of oncologic PET/CT of the chest

2017

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PET/CT is widely used for the evaluation of patients with thoracic malignancies. Although the levels of 18F-fluorodeoxyglucose (FDG) uptake are usually high in neoplastic diseases, they can also be physiological, due to artifacts. In addition, FDG uptake can occur in benign conditions such as infectious, inflammatory, and iatrogenic lesions. Furthermore, some malignant tumors, such as adenocarcinoma in situ (formerly known as bronchoalveolar carcinoma) and carcinoid tumors, may not show FDG uptake. Here, we illustrate the main pitfalls and artifacts in the interpretation of the results of oncologic PET/CT of the chest, outlining strategies for avoiding misinterpretation.

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PET/CT in the evaluation of pulmonary solitary nodule

Cited by 2 publications

References 7 publications

Differential diagnosis of solitary pulmonary nodules with dual-source spiral computed tomography

Differential diagnosis of solitary pulmonary nodules with dual-source spiral computed tomography

Pitfalls and artifacts in the interpretation of oncologic PET/CT of the chest

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