Retroperitoneal Ewing's sarcoma/embryonal tumor: a rare differential diagnosis of back pain

Reis, Fabiano; Macedo, Ermelinda; França, Marcondes C.; Amstalden, Eliane Maria Ingrid; Appenzeller, Simone

doi:10.1590/0100-3984.2015.0236

Cited by 7 publications

(5 citation statements)

References 5 publications

(7 reference statements)

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“…13 On imaging, retroperitoneal EES can be visually distinguished by its considerable size, presence of hemorrhaging, and invasiveness, along with involvement of the paraspinal region. [13][14][15] Previous reports on the imaging characteristics of EES focused on CT, MRI, and PET/CT, with only a few cases related to CEUS. EES has been reported to be a homogeneous and hypoechoic mass with internal vascular hyperplasia, cystic degeneration/necrosis, and calcification in about 10% of cases detected using conventional US.…”

Section: Discussionmentioning

confidence: 99%

“…A single‐center study in Korea involving 70 patients showed that retroperitoneal EES accounted for 5.71% (4/70) of all EES sites, and of those with retroperitoneal EES all presented with a single large solid retroperitoneal mass 13 . On imaging, retroperitoneal EES can be visually distinguished by its considerable size, presence of hemorrhaging, and invasiveness, along with involvement of the paraspinal region 13–15 . Previous reports on the imaging characteristics of EES focused on CT, MRI, and PET/CT, with only a few cases related to CEUS.…”

Section: Discussionmentioning

confidence: 99%

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Retroperitoneal Ewing's sarcoma in a woman with advanced breast cancer delineated by contrast‐enhanced ultrasound: A case report

Luo,

Mo,

Zhu

et al. 2023

Sonography

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Extraosseous Ewing's sarcoma is a malignant mesenchymal tumor much rarer than skeletal Ewing's sarcoma. The synchronous or metachronous occurrence of advanced breast cancer with retroperitoneal Ewing's sarcoma is extremely rare. To date, only a few cases of extraosseous Ewing's sarcoma with contrast‐enhanced ultrasound findings have been reported. This study aims to report a case of a retroperitoneal Ewing's sarcoma in a 39‐year‐old woman with advanced breast cancer, where grayscale ultrasound, contrast‐enhanced ultrasound, and computed tomography findings were included. To our knowledge, this is the first reported case of ultrasound and contrast‐enhanced ultrasonography manifestation of retroperitoneal Ewing's sarcoma as a second primary tumor.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Retroperitoneal Ewing's sarcoma in a woman with advanced breast cancer delineated by contrast‐enhanced ultrasound: A case report

Luo,

Mo,

Zhu

et al. 2023

Sonography

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“…Noteworthy, the vast majority of patients with CLBP will not benefit from surgery, which remains indicated only in selected patients with functional disabilities or with refractory pain despite multiple nonsurgical attempted treatments [ 78 ]. If CLBP is not associated with spinal causes, reasons should be searched in other diseases, such as neoplasia, retroperitoneal cancers [ 79 ], inflammatory arthritis, infections [ 80 ], or other uncommon reported causes such as the engorgement of the epidural venous plexus secondary to inferior vena cava thrombosis [ 81 ].…”

Section: Clinical Considerations In Chronic Low Back Painmentioning

confidence: 99%

Spinal Cord Stimulation in Chronic Low Back Pain Syndrome: Mechanisms of Modulation, Technical Features and Clinical Application

Guzzi

Torre

et al. 2022

Healthcare

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Chronic low-back pain (CLBP) is a common disease with several negative consequences on the quality of life, work and activity ability and increased costs to the health-care system. When pharmacological, psychological, physical and occupational therapies or surgery fail to reduce CLBP, patients may be a candidate for Spinal Cord Stimulation (SCS). SCS consists of the transcutaneous or surgical implantation of different types of electrodes in the epidural space; electrodes are then connected to an Implanted Pulse Generator (IPG) that generates stimulating currents. Through spinal and supraspinal mechanisms based on the “gate control theory for pain transmission”, SCS reduces symptoms of CLBP in the almost totality of well-selected patients and its effect lasts up to eight years in around 75% of patients. However, the evidence in favor of SCS still remains weak, mainly due to poor trial methodology and design. This narrative review is mainly addressed to those professionals that may encounter patients with CLBP failing conventional treatments. For this reason, we report the mechanisms of pain relief during SCS, the technical features and some clinical considerations about the application of SCS in patients with CLBP.

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“…ASPS generally arises in skeletal muscles of lower limbs and needs to be differentiated from Ewing’s sarcoma/embryonal tumor (ES/ET). ES/ET should be suspected in young adults presenting with a large heterogeneous mass in their extremities ( 3 ). Although ASPS is an indolent tumor, the hematogenous spread of the tumors to other tissues, usually pulmonary metastases, tends to occur early, indicating the aggressive behavior of ASPS and portends a poor prognosis.…”

Section: Introductionmentioning

confidence: 99%

The dynamic contrast enhanced-magnetic resonance imaging and diffusion-weighted imaging features of alveolar soft part sarcoma

Lv,

Xue,

Huang

et al. 2023

Quant Imaging Med Surg

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Background Alveolar soft part sarcoma (ASPS) is a rare type of soft tissue sarcoma that predominantly affects adolescents and young adults. Early diagnosis of ASPS is crucial for optimal therapeutic planning and improving prognosis, but its diagnostic features are not well delineated. This study aimed to retrospectively analyze the imaging features of ASPS with an emphasis on the dynamic contrast-enhanced-magnetic resonance imaging (DCE-MRI) and diffusion-weighted imaging (DWI) findings to identify imaging findings that might suggest the diagnosis to radiologists. Methods The imaging features of 34 patients with pathologically proven limb ASPS were retrospectively analyzed. A total of 23 underwent DCE-MRI, and 12 underwent DWI. Results Among the 34 cases of ASPS, 31 tumors were in the lower extremities, and 3 were in the upper extremities. The maximum tumor diameters ranged from 3.0 to 19.4 cm (mean, 8.7±3.96 cm). A total of 28 cases had well-defined borders. The masses demonstrated heterogeneous high signal intensity on T2-weighted imaging (T2WI) and the fat-suppressed (FS) T2WI sequence and slight hyperintensity on T1-weighted imaging (T1WI). A total of 25 lesions had thin hypointense bands on T1WI and T2WI. Intra- and peri-tumoral tubular areas of flow void were exhibited on both T1WI and T2WI in all cases. A total of 12 cases showed a high signal on DWI, and the mean apparent diffusion coefficient (ADC) value was (0.86±0.07)×10 –3 mm 2 /s [range, (0.6–1.4)×10 –3 mm 2 /s]. Persistent remarkable enhancement of the lesion was displayed on contrast-enhanced scans. The time-intensity curves (TICs) of 23 masses showed early arterial enhancement and slow washout of contrast. Conclusions ASPS most commonly presents in the lower extremities of adolescents or young adults. Hyperintense T1WI, T2WI, and DWI signals, low ADC, flow voids, early arterial enhancement are frequent MRI features.

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Retroperitoneal Ewing's sarcoma/embryonal tumor: a rare differential diagnosis of back pain

Cited by 7 publications

References 5 publications

Retroperitoneal Ewing's sarcoma in a woman with advanced breast cancer delineated by contrast‐enhanced ultrasound: A case report

Retroperitoneal Ewing's sarcoma in a woman with advanced breast cancer delineated by contrast‐enhanced ultrasound: A case report

Spinal Cord Stimulation in Chronic Low Back Pain Syndrome: Mechanisms of Modulation, Technical Features and Clinical Application

The dynamic contrast enhanced-magnetic resonance imaging and diffusion-weighted imaging features of alveolar soft part sarcoma

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