Massive thymoma of the mid-posterior mediastinum: an unprecedented case in a young adult

Abstract

We report an unprecedented case of ectopic thymoma in a young adult. A 33-year-old male presented with a 10-day history of non-productive cough and fever. Investigation revealed mediastinal widening without pulmonary involvement. Computed tomography showed a large mass-14.8 × 10.8 × 8.4 cm-in the mid-posterior mediastinum, and a biopsy obtained by video-assisted thoracoscopy indicated that the mass was a tumor. Immunohistochemistry showed combined thymoma type AB1. Because of the considerable proportions of the tumor and its close proximity to major structures, the patient was treated with chemotherapy.

Type-A Thymoma in a 56-Year-Old Male: A Case Report

“…The cell boundaries are hard to see, have pale eosinophilic cytoplasm, irregular oval nuclei, mild pleomorphic, pale chromatin, clear nuclear membrane, and nucleoli are among the conspicuous structures; type B2 thymoma are blue (due to dense lymphocytes), fibrous and lobular (irregular) tumor capsules, with epithelial cell groups (≥ 3 cells) spread among single lymphocyte / poorly differentiated cells. They have a round oval of nuclei, vesicular chromatin, a small promolentnucleoli, and focal anaplasia; in type B3 thymoma the lobes are separated by fibrous septa, pushing border, prominent perivesicular space with palisading epithelium, polygonal cells with eosinophilic/ clear cytoplasm, mild/moderate atypical, round/ elongated/grooved/raisinoid nuclei and nucleoli which are inconspicuous/prominent (4,(13)(14)(15)(16).…”