Laryngeal schwannoma: a case report with emphasis on sonographic findings

Souza, Luís Ronan Marquez Ferreira de; Nicola, Harley De; Yamasaki, Rosiane; Pedroso, José Eduardo de Sá; Brasil, Osíris de Oliveira Camponês do; Yamashita, H

doi:10.1590/0100-3984.2013.1695

Cited by 7 publications

(7 citation statements)

References 11 publications

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“…Among the 479 articles resulting from our literature search, 60 primary research papers fulfilled our criteria ( Figure 1 ), providing a total of 74 laryngeal schwannoma patients for combined analysis ( Table 1 and Supplemental Tables S1 and S2, available in the online version of the article). 2-61 The included studies consisted primarily of single case reports (n = 55), 4 reports of 2 cases, and 1 larger case series of 11 patients. The mean age at diagnosis was 43.4 years, with women presenting at a later age compared with men (47.3 years vs 32.8, P < .05).…”

Section: Resultsmentioning

confidence: 99%

Diagnosis and Treatment of Laryngeal Schwannoma: A Systematic Review

Tulli

Bondi

Smart

et al. 2017

Otolaryngol.--head neck surg.

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Objective This review summarizes the clinical features, diagnostic workup, and surgical treatment of laryngeal schwannoma with the aim of providing guidance for the management of this rare disease. The collated data allowed the statistical testing of several hypotheses, including the efficacy of endoscopic vs open surgical intervention and the usefulness of preoperative biopsy. Data Sources PubMed, Google Scholar, Cochrane, and SCOPUS. Review Methods Basic epidemiological and clinical presentation data were collated together with details of diagnostic image modality, lesion attributes, and the use of preoperative biopsy. Surgical approach to intervention and outcome was also collated and simple statistical analyses applied. Results The 60 original articles selected provided a combined cohort of 74 patients for review. The combined data revealed that schwannoma with pedunculated morphology were always safely removed by endoscopic resection regardless of size and should be treated as a separate entity. Of the nonpedunculated schwannoma, larger tumors were more likely to undergo an open approach, which in turn was associated with higher rates of tracheotomy and postoperative vocal fold paralysis. The small cohort did not reveal a significant association between surgery type and persistent disease. Interestingly, the data revealed a significant association between the use of incisional biopsy and persistent disease. Cases exhibiting extralaryngeal extension of the lesion were shown to exclusively belong to patients with neurofibromatosis/schwannomatosis syndromes. Conclusions Taken together, these findings suggest that incisional biopsy should be avoided, and given the benign nature of the pathology, the least invasive radical approach should be employed.

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Section: Resultsmentioning

confidence: 99%

Diagnosis and Treatment of Laryngeal Schwannoma: A Systematic Review

Tulli

Bondi

Smart

et al. 2017

Otolaryngol.--head neck surg.

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“…A series of recent studies published in Brazil have highlighted the relevance of ultrasonography in the diagnosis and treatment of several diseases ( 1 - 15 ) . Ultrasonography is utilized in dermatology since the 1970's to evaluate skin thickening ( 16 ) .…”

Section: Introductionmentioning

confidence: 99%

Study of the skin anatomy with high-frequency (22 MHz) ultrasonography and histological correlation

et al. 2015

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The present essay is aimed at getting the radiologist familiar with the basic histological skin structure, allowing for a better correlation with sonographic findings. A high-frequency (22 MHz) ultrasonography apparatus was utilized in the present study. The histological analysis was performed after the skin specimens fixation with formalin, inclusion in paraffin blocks and subsequent staining with hematoxylin-eosin. The authors present a literature review showing the relationship between sonographic and histological findings in normal cutaneous tissue, and discuss the technique for a better performance of the sonographic scan. High-frequency ultrasonography is an excellent tool for the diagnosis of different skin conditions. However, as this method is operator-dependent, it is crucial to understand the normal skin structure as well as the correlation between histological and sonographic findings.

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“…Some researchers also use ultrasonography to assist in the diagnosis of head and neck schwannoma, 20–22 but the clinical application of such imaging is limited in laryngeal schwannoma. 6,17,23…”

Section: Discussionmentioning

confidence: 99%

“…Some researchers also use ultrasonography to assist in the diagnosis of head and neck schwannoma, [20][21][22] but the clinical application of such imaging is limited in laryngeal schwannoma. 6,17,23 For differential diagnosis, other submucosal lesions such as laryngocele, laryngeal cyst, adenoma, chondroma, mucocele, lipoma, and neurofibroma should be considered. 6 Among these, particular attention should be paid to neurofibroma.…”

Section: Discussionmentioning

confidence: 99%

Paraglottic space schwannoma: a case report and literature review

Chen

Guo

et al. 2022

J Int Med Res

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Neurogenic tumors located in the larynx are extremely rare. Among them, schwannoma is a benign encapsulated tumor originating from Schwann cells, which form nerve fiber sheaths in the peripheral nervous system. We herein report a case of a schwannoma arising from a rare subsite of the larynx and review the literature on laryngeal schwannoma. The case involved a woman with a 1-month history of globus pharyngeus and dysphagia without dysphonia. Rigid laryngoscopy and magnetic resonance imaging showed a large submucosal bulge toward the medial wall of the right pyriform fossa, pushing the right false and true vocal cords and aryepiglottic fold inward. A transcervical approach was used to completely excise the tumor without incisional biopsy or preliminary tracheotomy. Histology confirmed a benign schwannoma originating from the right paraglottic space, which was extremely rare. During follow-up, no evidence of recurrence or a residual mass was found. The transcervical approach is a useful and less invasive treatment for laryngeal schwannoma located in the paraglottic space.

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Laryngeal schwannoma: a case report with emphasis on sonographic findings

Cited by 7 publications

References 11 publications

Diagnosis and Treatment of Laryngeal Schwannoma: A Systematic Review

Diagnosis and Treatment of Laryngeal Schwannoma: A Systematic Review

Study of the skin anatomy with high-frequency (22 MHz) ultrasonography and histological correlation

Paraglottic space schwannoma: a case report and literature review

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