Complete genome sequence of Deltapapillomavirus 4 (bovine papillomavirus 2) from a bovine papillomavirus lesion in Amazon Region, Brazil

Abstract

The complete genome sequence of bovine papillomavirus 2 (BPV2) from Brazilian Amazon Region was determined using multiple-primed rolling circle amplification followed by Illumina sequencing. The genome is 7,947 bp long, with 45.9% GC content. It encodes seven early (E1, E2,E4, E5, E6,E7, and E8) and two late (L1 and L2) genes. The complete genome of a BPV2 can help in future studies since this BPV type is highly reported worldwide although the lack of complete genome sequences available.

Clinicopathological characteristics and papillomavirus types in cutaneous warts in bovine

“…No relationship between BPV types and the macroscopic aspect or anatomical site of the lesion could be established. This lack of association can be attributed to co-infections, which has been reported to occur [3,7,10,13]; recently, seven different BPV types were detected in the same lesion [13]. In the present study, it was not possible to detect more than one BPV type in the same lesion; however, different BPV types were detected in animals from three herds and in different anatomic sites from one animal.…”

“…In Brazil, these BPVs were already detected in Rio Grande do Sul [28] and in other Southern states [8-10, 19, 31]. They have also been detected in North-East [3,7], Amazon [12,13,28], and Southeast [19] Brazilian regions. The fact that these types have been detected in different herds and in different years indicates that they are frequent types in the bovine population.…”

Papillomaviruses in ruminants: An update

“…The majority of BPV type‐specific prevalence data are from Japan and Brazil. Brazil is one of the largest beef and milk producer in the world, and 21 of 23 BPV types were detected and described here, as well as a great number of putative new types (Batista et al., ; Carvalho, Batista, Silva, Balbino, & Freitas, ; Da Silva et al., , ; Daudt, da Silva, Cibulski, et al., ; Daudt, da Silva, Streck, et al., ; Lunardi, Alfieri, et al., ; Lunardi et al., ). The BPV type‐specific distribution and their association with specific lesions in cattle are summarized in Table .…”