Anal polyp caused by Schistosoma mansoni

Abstract

We describe a schistosomal polyp in the anus of a 24-year-old patient, born in Viçosa, State of Minas Gerais, and living in Belo Horizonte, State of Minas Gerais. From 8 to 13 years of age, he swam in the rivers that bathe Viçosa. The histopathological examination has shown a lesion, lined by a keratinized squamous epithelium, ulcerated, with granulomas, centered or not by Schistosoma mansoni egg, laid, in loco, by the female present in the vascular lumen of a vein of the hemorrhoidal plexus. There was also a diffuse, nonspecific inflammation in the dermis. The patient was treated with praziquantel. Four months after the treatment, sigmoidoscopy showed a normal rectal mucosa, and negative oogram and stool tests. Ultrasound of abdomen was normal.

Eggs, Worms, or Both? Chronic Active Schistosomiasis Presenting as Cirrhosis and Colonic Polyps

“…It is unusual for schistosomiasis to have evidence of infection after the fibrotic phase has occurred. Rarely, worms may be found alive, mating, or dead within the inflammatory reaction 5 ; however, this is the first case to describe colonic polyps with male and female worms and associated eggs on histology. It is remarkable to have an active infection years after living in a nonendemic region.…”

Schistosomal (bilharzial) polyps: Travel through the colon and beyond

“…In the submucosa, the trapped ova produce a TH2 cell-mediated inflammatory response with many cellular and chemical elements being recruited to the area and granuloma formation begins. The hallmark of the granuloma is infiltration by eosinophils (eosinophilic granuloma)[ 1 ], however, during this exudative stage of granuloma formation, other inflammatory cells are seen including the epithelioid macrophages and mononuclear cells[ 1 , 5 ].…”

“…Stage of proliferation: Within the granuloma necrosis occur[ 5 ]. Healing of the developed necrotic foci is associated with fibrous connective tissue formation.…”

Does Schistosoma Mansoni Facilitate Carcinogenesis?

“…The primary presenting symptoms of intestinal schistosomiasis are usually tenesmus and the rectal passage of blood and mucous and bloody diarrhea [144]. Egg deposition and granuloma formation eventually lead to acute then chronic schistosomal colitis and are commonly associated with polyp formation [145][146][147][148]. The preferential site of schistosomal polyps is the rectum, followed by the sigmoid colon [149].…”