Crimean-Congo hemorrhagic fever with hemophagocytic lymphohistiocytosis

Yakut, Nurhayat; Kepenekli, Eda; Doğru, Ömer

doi:10.1590/0037-8682-0438-2020

Cited by 5 publications

(1 citation statement)

References 3 publications

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“…There is usually evidence of hepatitis; severely ill patients may experience rapid kidney deterioration and sudden liver or pulmonary failure following an illness. The CCHF mortality rate is approximately 30%, with deaths occurring in the second week of illness ( Yakut et al, 2021 ; WHO, 2022a ). In brief, over the last decade, considerable progress has been made in exploring cellular components involved in tick-host-pathogen interactions; however, there is limited knowledge in the case of CCHFV due to its high-level containment requirement.…”

Section: Crimean-congo Hemorrhagic Fever Virusmentioning

confidence: 99%

Geographical distribution and pathogenesis of ticks and tick-borne viral diseases

Shah

Wang

et al. 2023

Front. Microbiol.

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Ticks are obligatory hematophagous arthropods that harbor and transmit infectious pathogens to humans and animals. Tick species belonging to Amblyomma, Ixodes, Dermacentor, and Hyalomma genera may transmit certain viruses such as Bourbon virus (BRBV), Dhori virus (DHOV), Powassan virus (POWV), Omsk hemorrhagic fever virus (OHFV), Colorado tick fever virus (CTFV), Crimean-Congo hemorrhagic fever virus (CCHFV), Heartland virus (HRTV), Kyasanur forest disease virus (KFDV), etc. that affect humans and certain wildlife. The tick vectors may become infected through feeding on viraemic hosts before transmitting the pathogen to humans and animals. Therefore, it is vital to understand the eco-epidemiology of tick-borne viruses and their pathogenesis to optimize preventive measures. Thus this review summarizes knowledge on some medically important ticks and tick-borne viruses, including BRBV, POWV, OHFV, CTFV, CCHFV, HRTV, and KFDV. Further, we discuss these viruses’ epidemiology, pathogenesis, and disease manifestations during infection.

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Section: Crimean-congo Hemorrhagic Fever Virusmentioning

confidence: 99%