Prostate cancer mortality in Brazil 1990-2019: geographical distribution and trends

Abstract

Introduction:To analyze the trend of prostate cancer mortality in the Brazilian population of 40 years of age and above. Methods: Time series ecological study of the mortality rates due to prostate cancer in men of 40 years of age and above, using data from the Global Burden of Disease 2019 (GBD). Age-standardized mortality rates were calculated, as well as the age-standardized rates by the GBD for the global population, per 100,000 inhabitants, for Brazil and its States, from 1990 to 2019. The annual average percent change (AAPC) was calculated to identify the mortality trends in Brazil, through linear regression using the Joinpoint Regression Program. Results: The standardized rates of prostate cancer mortality in Brazil were 76.89 in 1990 and 74.96 deaths for every 100 thousand men ≥ 40 years of age in 2019, with a stability trend. By age group, it was observed a decreasing trend up to 79 years of age, and an increasing trend as of 80 years of age. The state of Bahia showed the highest increase in mortality in the period (1.2%/year), followed by Maranhão and Pernambuco (1.0 and 0.9%/year). A decrease of prostate cancer mortality was found in the Federal District,

Disparities in the burden of prostate cancer and its trends in the Western Pacific Region, 1990-2019

“…Meanwhile, PC mortality decreased, indicating technologies on screening, diagnosis, and treatment were improving. (12,13) The reason for this rising trend of PC incidence and prevalence is in various aspects, which might include greater longevity and population aging, increasing disease risks associated with economic growth, the widespread of PC screening, especially prostate-speci c antigen (PSA) testing, and the improvement of cancer registries. (14)(15)(16)(17) The European Region and Region of the Americas had the highest DALYs rate of PC from 1990 to 2019, while the DALYs rates of PC in the WPR, by contrast, were relatively low except in Australia.…”

Distribución espacial del cáncer de próstata a escala regional y factores demográficos y sociocoeconómicos: Megalópolis del Centro de México (2013-2020)

“…Entre los trabajos a escala nacional son destacables los estudios de Costa Rica (Murillo y González, 2020), Brasil (Colbachini et al, 2022), Eslovaquia (Vilinová, 2020), Iraq (Mohammed Al-Hashimi, 2021 o Estados Unidos de América . También existen algunos estudios a nivel nacional que constatan los desequilibrios espaciales en el cáncer de próstata, en particular sobre las dinámicas, como en el caso de Brasil para 1990-2019 (Iser et al, 2022) La mayor parte de los trabajos con enfoque espacial se han realizado en los últimos años, momento en el que la epidemiología espacial en general se ha desarrollado y expandido. A escala nacional predominan los análisis de la incidencia, en el estudio de Brasil se centra en la mortalidad, análisis de su distribución espacial y tendencias, en tanto que el de Estados Unidos analiza los diferentes patrones de la incidencia del cáncer de próstata según raza.…”