Prevalence of HCV infection in a prison population of the greater Florianópolis area

Felisberto, Mariano; Saretto, Antonio Adalberto; Wopereis, Sandro; Machado, Marcos José; Spada, Celso

doi:10.1590/0037-8682-0143-2019

Cited by 3 publications

(1 citation statement)

References 11 publications

(9 reference statements)

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“…Viral hepatitis is a global phenomenon, with the disease burden varying on a daily basis. WHO gives a prevalence rate of 1.0% for hepatitis C, with a previously reported increase from 2.3% to 2.8% between 1990 and 2005, according to the Global Burden of diseases, injuries, and risk factors 2010 (26,27) . Many studies have revealed an increasing prevalence of hepatitis B amongst specific risk groups like medical waste handlers, blood donors, and reproductive age (5,28,29) .…”

Section: Discussionmentioning

confidence: 98%

A Cross-Sectional Screening Survey on the Seroprevalence of Hepatitis B and Hepatitis C Amongst the General Population of Rural Districts of Sindh, Pakistan

Asghar

Rasheed

Hassan

et al. 2021

Arq. Gastroenterol.

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BACKGROUND: Viral hepatitis is a global phenomenon, with the disease burden varying on a daily basis. Amongst chronic infections, hepatitis B virus and hepatitis C virus (HCV) are egregiously linked to severe health-related complications, with a worldwide prevalence of 248 million and 71 million respectively. Amongst the developing world, a hand full of countries are exhibiting a gross decline in chronic viral infection prevalence, like Bangladesh. While countries such as India have a consistent prevalence, Pakistan bears one of the largest proportions of chronic viral hepatitis globally with increasing trends shown year-by-year. Various old literature texts have stated an approximate national prevalence rate around 2.6% and 5.3% of hepatitis B and C respectively. OBJECTIVE: The objective of this study was to determine the current seroprevalence rates of chronic viral hepatitis amongst the general population of rural Sindh using a screening program to determine the current disease burden. METHODS: An observational, cross-sectional survey based on a screening program was conducted in 5 districts with a combined population of over 6.5 million. The screening was carried out via the administration of various camps with the assistance of local social workers and welfare organizations. A total of 24,322 individuals met the inclusion criteria and were screened through (HBsAg/HCV) rapid test cassette (WC) Imu-Med one-step diagnostic test. RESULTS: Hepatitis B was found positive in 964 (3.96%) individuals including 421 (43.67%) males and 543 (56.32%) females, while hepatitis C was positive in 2872 (11.80%) individuals including 1474 (51.32%) males and 1398 (48.67%) females. The prevalence amongst the districts varied between 0.97% and 9.06% for hepatitis B, and 1.61% and 29.50% for hepatitis C, respectively. Umerkot was found to be the most prevalent district amongst rural Sindh, while Badin had the least number of seropositive people. The second most prevalent district of the study population was found to be Tando Allahyar followed by Mirpur Khas. The combined seroprevalence of 15.76% was calculated for hepatitis B and C together amongst the five studied districts of rural and peri-urban Sindh. CONCLUSION: The alarmingly high prevalence rates revealed in our study warrant the urgent need to generate multiple effective strategies in the region to enhance awareness amongst the general population regarding screening, prevention, and prompt treatment of the disease.

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Section: Discussionmentioning

confidence: 98%

A Cross-Sectional Screening Survey on the Seroprevalence of Hepatitis B and Hepatitis C Amongst the General Population of Rural Districts of Sindh, Pakistan

Asghar

Rasheed

Hassan

et al. 2021

Arq. Gastroenterol.

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Hepatitis C prevalence in incarcerated settings between 2013–2021: a systematic review and meta-analysis

et al. 2022

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Background The introduction of highly effective direct-acting antiviral therapy has changed the hepatitis C virus (HCV) treatment paradigm. However, a recent update on HCV epidemiology in incarcerated settings is necessary to accurately determine the extent of the problem, provide information to policymakers and public healthcare, and meet the World Health Organization's goals by 2030. This systematic review and meta-analysis were performed to determine the prevalence of HCV Ab and RNA in incarcerated settings. Methods For this systematic review and meta-analysis, we searched PubMed, Embase, Scopus, and Web of Science for papers published between January 2013 and August 2021. We included studies with information on the prevalence of HCV Ab or RNA in incarcerated settings. A random-effects meta-analysis was done to calculate the pooled prevalence and meta-regression to explore heterogeneity. Results Ninety-two unique sources reporting data for 36 countries were included. The estimated prevalence of HCV Ab ranged from 0.3% to 74.4%. HCV RNA prevalence (available in 46 sources) ranged from 0% to 56.3%. Genotypes (available in 19 sources) 1(a) and 3 were most frequently reported in incarcerated settings. HCV/HIV coinfection (available in 36 sources) was highest in Italy, Estonia, Pakistan, and Spain. Statistical analysis revealed that almost all observed heterogeneity reflects real differences in prevalence between studies, considering I2 was very high in the meta-analysis. Conclusions HCV in incarcerated settings is still a significant problem with a higher prevalence than in the general population. It is of utmost importance to start screening for HCV (Ab and RNA) in incarcerated settings to give clear, reliable and recent figures to plan further treatment. This is all in the context of meeting the 2030 WHO targets which are only less than a decade away. Trial registration PROSPERO: CRD42020162616

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Prevalence of Hepatitis B and C Among Stroke Patients in Khairpur

Jamali,

Ahmad,

Hussain

et al. 2023

PBMJ

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Hepatitis C virus (HCV) infection is associated with a high likelihood of ischaemic cerebral stroke. Patients with HCV-related stroke tend to be younger, have fewer traditional risk factors, and have elevated levels of systemic inflammation. Objective: To investigate the correlation between hepatitis C virus (HCV) infection, hepatitis B virus (HBV) infection and their functional outcome of stroke. Methods: This cross-sectional study included 157 individuals diagnosed with all types of strokes. Every patient underwent meticulous history collection and comprehensive clinical and neurological assessment. HCV infection was diagnosed using a quantitative HCV RNA assay. Results: Out of the 157 patients, 15 (29.4 %) had Hepatitis B, and thirty-six (70.6 %) had hepatitis C, with an overall prevalence of 51 (32.5%). Among the male patients, HBV and HCV were present in 8 (27.6%) and 21 (72.4%), respectively, with an overall prevalence of 29 (56.9%) (Table 2). Similarly, among female patients, HBV and HCV were present in 7 (31.8%) and 15 (68.8%) patients, respectively, with an overall prevalence of 22 (43.1%). Conclusions: An increased prevalence of Hepatitis C Virus (HCV) and Hepatitis B Virus (HBV) has been noted in patients who have experienced a stroke.

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Prevalence of HCV infection in a prison population of the greater Florianópolis area

Cited by 3 publications

References 11 publications

A Cross-Sectional Screening Survey on the Seroprevalence of Hepatitis B and Hepatitis C Amongst the General Population of Rural Districts of Sindh, Pakistan

A Cross-Sectional Screening Survey on the Seroprevalence of Hepatitis B and Hepatitis C Amongst the General Population of Rural Districts of Sindh, Pakistan

Hepatitis C prevalence in incarcerated settings between 2013–2021: a systematic review and meta-analysis

Prevalence of Hepatitis B and C Among Stroke Patients in Khairpur

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