Zika virus: - a review of the main aspects of this type of arbovirosis

Abstract

The objective of this study was to integrate findings related to Zika virus from the scientific literature. An integrative review of Medline was conducted, and data search was performed using the Health Sciences Descriptor Zika virus and the following filters: full texts available; studies in humans; full articles; and publications in Portuguese, French, English, and Spanish. After application of the filters, followed by reading of the titles, abstracts, and full texts, 44 studies were included in the review, for which content analysis was performed. A large part of the literature comprised review articles (84%; N=37); the majority was in English (95%, N=42). In 2016, 84% (N=37) of our sample articles was published, while in 2017, 16% (N=7) was published. The main form of viral transmission was thorough the mosquito Aedes aegypti (N=30). In addition, sexual transmission (N=09), transmission through blood transfusion (N=16), vertical transmission (N=21) and transmission from occupational activities (N=03) occurred. It was possible to diagnose the disease by testing blood (N=22), urine (N=14), saliva (N=06), semen/sperm (N=03), cerebrospinal and amniotic fluid, and other tissues (N=02). Symptomatology occurred in 1-5 people (N=10) between 3 and 7 days after a mosquito bite (N=09). Complications observed were Guillain Barré syndrome (N=27); neurological Zika syndrome (N=27); meningitis, meningoencephalitis, and myelitis (N=07); deaths and/or newborns (N=03). The review provides scientific evidence that contributes to the care, planning and implementation of public policies.

Vector Competence of Aedes aegypti, Aedes albopictus and Culex quinquefasciatus from Brazil and New Caledonia for Three Zika Virus Lineages

“…The number of cases in Brazil peaked in 2016 with nearly 215,320 probable Zika cases [ 12 ], followed by 17,593 and 10,768 reported cases annually between 2017 and 2019 [ 13 , 14 ]. The occurrence of microcephaly and other congenital neurological malformations associated with ZIKV infections has been described worldwide [ 15 , 16 , 17 ], and the virus continues to be considered an important threat [ 18 ].…”

Diagnostic Advances in Acute Viral Meningitis: Any Novelty for the Physician?

“…9,10 The mosquito Aedes aegypti was most commonly accused of viral transmission, followed by sexual transmission, vertical transmission, and blood transfusion. 11 Its diagnosis is somewhat elusive. Blood and urine testing were proved most useful in acute diagnosis.…”

In vitro antiviral activity against Zika virus from a natural product of the Brazilian red seaweed Bryothamnion triquetrum

“…ZIKV often causes self-limited and mild illness commonly characterized by fever, rash, myalgia, arthralgia, and conjunctivitis (Dias et al, 2018). However, severe manifestations were associated with this disease, such as Guillain-Barré syndrome (Cao-Lormeau et al, 2016) and Zika congenital syndrome in infants (Brasil et al, 2016;Honein et al, 2017).…”