Cavernous Sinus Ewing's Sarcoma

Abstract

Ewing's sarcomas (ES) are malignant tumors mostly found in children and young adults 1,2,3. There are only six cavernous sinus ES reported in the literature 1,2,3,4,5. A 21-year-old male presented with diplopia and left VI nerve palsy. Imaging revealed a lesion in the left cavernous sinus (Figure 1). A pretemporal craniotomy was performed with partial resection and recovery. The tumor consisted of small round cells on histopathological examination (Figure 2), positive for CD99, CD56, BCL-2 and Ki 67 positive in 10% of the cells and were negative for desmin, synaptophysin, GFAP, S-100 protein, CLA, cytokeratin 7 and 20, 34BE12, AE1/AE3, consistent with Ewing's sarcoma.