Paleoparasitology: the origin of human parasites

Araújo, Adauto; Reinhard, Karl J.; Ferreira, Luiz Fernando; Pucu, Elisa; Chieffi, Pedro Paulo

doi:10.1590/0004-282x20130159

Cited by 43 publications

(40 citation statements)

References 28 publications

(34 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…For Chagas disease, the Latinamerican trypanosomiasis 31 , caused by trypanosoma cruzi, the detailled immunoglobulin response pattern is not available. But reports 13 which state normal CSF values or only slight increase of proteins may represent the different pathomechanism as an expression of the parasitism described 31 .…”

Section: Neurotrypanosomiasismentioning

confidence: 99%

See 1 more Smart Citation

Cerebrospinal fluid data compilation and knowledge-based interpretation of bacterial, viral, parasitic, oncological, chronic inflammatory and demyelinating diseases. Diagnostic patterns not to be missed in neurology and psychiatry

Reiber

2016

Arq. Neuro-Psiquiatr.

View full text Add to dashboard Cite

REVIEWCerebrospinal fluid data compilation and knowledge-based interpretation of bacterial, viral, parasitic, oncological, chronic inflammatory and demyelinating diseases. Diagnostic patterns not to be missed in neurology and psychiatry Liquido cefalorraquidiano: compilação dos dados e interpretação avançada de doenças bacterianas, virais, parasitarias, oncológicas, inflamatórias cronicas e desmielinizantes. Padrões diagnósticos que não devem faltar em neurologia e psiquiatria Hansotto ReiberGeorg August-University, Former Neurochemistry Laboratory, Goettingen, Germany. AbstrACtThe analysis of intrathecal IgG, IgA and IgM synthesis in cerebrospinal fluid (CSF) and evaluation in combined quotient diagrams provides disease-related patterns. The compilation with complementary parameters (barrier function, i.e., CSF flow rate, cytology, lactate, antibodies) in a cumulative CSF data report allows a knowledge-based interpretation and provides analytical and medical plausibility for the quality assessment in CSF laboratories. The diagnostic relevance is described for neurological and psychiatric diseases, for which CSF analysis can't be replaced by other diagnostic methods without loss of information. Dominance of intrathecal IgM, IgA or three class immune responses give a systematic approach for Facial nerve palsy, Neurotrypanosomiasis, Opportunistic diseases, lymphoma, Neurotuberculosis, Adrenoleucodystrophy or tumor metastases. Particular applications consider the diagnostic power of the polyspecific antibody response (MRZ-antibodies) in multiple sclerosis, a CSF-related systematic view on differential diagnostic of psychiatric diseases and the dynamics of brain-derived compared to blood-derived molecules in CSF for localization of paracytes.Keywords: cerebrospinal fluid; immunoglobulins; antibody; nervous system diseases; clinical record. resumo A análise da síntese intratecal de IgG, IgA e IgM no liquido cefalorraquidiano (LCR) e a avaliação destas em diagramas com quocientes sugere padrões de diversas doenças. Estes dados, juntamente com outros parâmetros como a função de barreira, o fluxo liquórico, a citologia, o lactato e a pesquisa de anticorpos, integrados em uma ficha de paciente, permite uma interpretação baseada em conhecimento e permite também uma aferição da qualidade em laboratórios de LCR. A relevância diagnóstica é descrita para doenças neurológicas e psiquiátricas pois a análise do LCR não pode ser substituída por outros metódos diagnósticos sem perda de informação para o diagnóstico do paciente. O aumento da síntese intratecal de IgM, IgA ou das 3 classes de imunoglobulinas sugerem um diagnóstico sistemático de paralisia facial periférica, neurotripanosomiase, doenças oportunísticas, linfoma, neurotuberculose, adrenoleucodistrofia ou metástases de tumores cerebrais. A resposta poliespecífica de anticorpos contra sarampo, rubéola e varicela zoster (MRZ reação) é sugestiva de esclerose múltipla. Uma visão sistemática considera o diagnóstico diferencial de doenças psiquiátricas e doenças chrônicas. A...

show abstract

Section: Neurotrypanosomiasismentioning

confidence: 99%

“…But reports 13 which state normal CSF values or only slight increase of proteins may represent the different pathomechanism as an expression of the parasitism described 31 .…”

Section: Neurotrypanosomiasismentioning

confidence: 99%

Cerebrospinal fluid data compilation and knowledge-based interpretation of bacterial, viral, parasitic, oncological, chronic inflammatory and demyelinating diseases. Diagnostic patterns not to be missed in neurology and psychiatry

Reiber

2016

Arq. Neuro-Psiquiatr.

View full text Add to dashboard Cite

show abstract

“…Upon their arrival in the Americas, humans began be exposed to parasite species that circulate in the extant fauna (Araújo et al., 2013). Even now, though to a lesser extent, we are still exposed to the wild environment, its wildlife and their parasites.…”

Section: Introductionmentioning

confidence: 99%

Wild and synanthropic reservoirs of Leishmania species in the Americas

Roque

Jansen

2014

International Journal for Parasitology: Parasites and Wildlife

231

195

View full text Add to dashboard Cite

show abstract

“…As long as life has existed on earth, there have been parasites [ 1 ]. In fact, there is not a single organism that is protected against parasites [ 1 ].…”

Section: Introductionmentioning

confidence: 99%

A systematic review of zoonotic enteric parasitic diseases among nomadic and pastoral people

Barnes¹,

Davaasuren²,

Baasandagva³

et al. 2017

PLoS ONE

View full text Add to dashboard Cite

IntroductionZoonotic enteric parasites are ubiquitous and remain a public health threat to humans due to our close relationship with domestic animals and wildlife, inadequate water, sanitation, and hygiene practices and diet. While most communities are now sedentary, nomadic and pastoral populations still exist and experience unique exposure risks for acquiring zoonotic enteric parasites. Through this systematic review we sought to summarize published research regarding pathogens present in nomadic populations and to identify the risk factors for their infection.MethodsUsing systematic review guidelines set forth by PRISMA, research articles were identified, screened and summarized based on exclusion criteria for the documented presence of zoonotic enteric parasites within nomadic or pastoral human populations. A total of 54 articles published between 1956 and 2016 were reviewed to determine the pathogens and exposure risks associated with the global transhumance lifestyle.ResultsThe included articles reported more than twenty different zoonotic enteric parasite species and illustrated several risk factors for nomadic and pastoralist populations to acquire infection including; a) animal contact, b) food preparation and diet, and c) household characteristics. The most common parasite studied was Echinococcosis spp. and contact with dogs was recognized as a leading risk factor for zoonotic enteric parasites followed by contact with livestock and/or wildlife, water, sanitation, and hygiene barriers, home slaughter of animals, environmental water exposures, household member age and sex, and consumption of unwashed produce or raw, unprocessed, or undercooked milk or meat.ConclusionNomadic and pastoral communities are at risk of infection with a variety of zoonotic enteric parasites due to their living environment, cultural and dietary traditions, and close relationship to animals. Global health efforts aimed at reducing the transmission of these animal-to-human pathogens must incorporate a One Health approach to support water, sanitation, and hygiene development, provide education on safe food handling and preparation, and improve the health of domestic animals associated with these groups, particularly dogs.

show abstract

Paleoparasitology: the origin of human parasites

Cited by 43 publications

References 28 publications

Cerebrospinal fluid data compilation and knowledge-based interpretation of bacterial, viral, parasitic, oncological, chronic inflammatory and demyelinating diseases. Diagnostic patterns not to be missed in neurology and psychiatry

Cerebrospinal fluid data compilation and knowledge-based interpretation of bacterial, viral, parasitic, oncological, chronic inflammatory and demyelinating diseases. Diagnostic patterns not to be missed in neurology and psychiatry

Wild and synanthropic reservoirs of Leishmania species in the Americas

A systematic review of zoonotic enteric parasitic diseases among nomadic and pastoral people

Contact Info

Product

Resources

About