Position article and guidelines 2018 recommendations of the Brazilian Society of Rheumatology for the indication, interpretation and performance of nailfold capillaroscopy

Kayser, Cristiane; Bredemeier, Markus; Caleiro, Maria Teresa Correia; Capobianco, Karina Gatz; Fernandes, Tatiana; Fontenele, Sheila Márcia de Araújo; Freire, Eutília Andrade Medeiros; Lonzetti, Lílian Scussel; Miossi, Renata; Sekiyama, Juliana; Müller, Carolina de Souza

doi:10.1186/s42358-018-0046-4

Cited by 21 publications

(31 citation statements)

References 96 publications

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“…We used the recommendations issued by the Brazilian Society of Rheumatology (BSR) and the American College of Rheumatology (ACR) while reporting and analyzing NFC findings. 5,6 Accordingly the number of capillaries, normal morphological variants (namely, hairpin or U-shaped capillaries, tortuous capillaries, one cross capillaries, two cross capillaries, and meandering capillaries), architecture, and abnormal capillaries were noted. Normal architecture as described in the literature included homogeneous, regular, palisaded, and perpendicular capillaries to nailfold.…”

Section: Nfc Image Analysismentioning

confidence: 99%

“…Studies have shown good diagnostic accuracy of dermatoscope [1][2][3] and ophthalmoscope 4 to discriminate systemic sclerosis (SSc) from healthy control. 5 The current recommendation 5,6 is to examine a central 2-mm contiguous area in each digit Abnormalities like reduced density, capillary dropouts, enlarged capillaries, and giant capillaries are found in SSc, and the term "scleroderma pattern" is used to describe these findings. 7,8 NFC findings are categorized into early, active, and late patterns.…”

Section: Introductionmentioning

confidence: 99%

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Effect of skin phototype on quantitative nailfold capillaroscopy

Bairwa

Kavadichanda

Dunga

et al. 2022

Journal of Scleroderma and Related Disorders

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Objectives: To determine the impact of Fitzpatrick scale-based skin phototype on visualization of capillary density using nailfold capillaroscopy in healthy Indian adults. Methods: In this cross-sectional study, healthy adults were examined for nailfold capillaroscopy findings utilizing a portable capillary microscope at 800× magnification. Photographs of two contiguous areas measuring 1 mm2 each of the distal row of capillaries were captured. Images were captured from the central area of all fingers except thumb in both hands. Capillary density and morphology of nailfold capillaroscopies were assessed by two blinded assessors. The nailfold capillaroscopy parameters were compared between the Standard Fitzpatrick scale-based skin phototypes. Results: A total of 118 healthy adults were enrolled in the study. Type III, IV, V, and VI skin phototypes were seen in 27 (22.90%), 32 (27.19%), 29 (24.58%), and 30 (25.42%) participants, respectively. All participants (100%) had normal nailfold capillaroscopy morphology and architecture. Zero capillaries were visible in 11 fingers among 5 patients (4.24%) and all of them had Type VI phototype. The median capillary density per mm was 5.19 (interquartile range = 4.37–6.75) with 90 (76.27%) participants having less than seven capillaries. The median average capillary density was significantly different ( p-value < 0.0001) across Type III (8.13, interquartile range = 6.44–8.88), Type IV (5.67, interquartile range = 4.41–6.98), Type V (4.94, interquartile range = 4.19–5.38), and Type VI (4.53, interquartile range = 3.72–4.91) phototypes ( p < 0.05). Conclusion: The number of capillaries visualized during nailfold capillaroscopy decreases as the skin pigmentation increases. There is a need to redefine the nailfold capillaroscopy density and avascularity by taking skin phototype as one of the determinants before labeling a nailfold capillaroscopy finding with less visualized capillaries as abnormal.

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Section: Nfc Image Analysismentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Effect of skin phototype on quantitative nailfold capillaroscopy

Bairwa

Kavadichanda

Dunga

et al. 2022

Journal of Scleroderma and Related Disorders

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“…Discrete variations, such as tortuous, particularly elderly patients and "meandering" loops and a visible subpapillary venous plexus, may occur, particularly among light-skinned individuals. [17][18][19] These changes, which can be observed with age, remain within defined normal limits. Therefore, this result may not be an important limitation of our study.…”

Section: Discussionmentioning

confidence: 73%

Use of nailfold video capillaroscopy in polycythemia vera

Ersözlü¹,

Bakırcı²,

Sunu³

et al. 2021

Arch Rheumatol

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Objectives: In this study, we aimed to investigate capillary vessel diameters and structural changes of capillaries by using nailfold video-capillaroscopy in patients with Polycythemia Vera. Patients and Methods: This cross-sectional study was conducted with 24 patients (19 males, 5 females; mean age: 62.5±2 years; range, 50.2 to 68 years) with Polycythemia vera and 15 healthy controls (11 males, 4 females; mean age: 40±2 years; range, 36 to 44 years) between June 2016 and February 2017. Nailfold video-capillaroscopy was performed by an experienced rheumatologist, blinded to clinical data. The apical, arterial, and venous limb diameters of capillaries were measured and microvascular changes of capillaries were scored. Results: When capillaries were evaluated in terms of morphological structures, giant capillary was detected 67% in the patients with Polycythemia vera, while it was not detected in the control group. The arterial, venous and apical diameters of the capillaries were significantly higher in the patients with Polycythemia vera compared to the control group [(38.33 µm vs. 21.23 µm, p <0.001), (48.41 µm vs. 27.48 µm p <0.001), (55.80 µm etc. 36.61 µm, p <0.001), respectively]. Conclusion: The presence of giant capillaries and the marked increase of arterial, venous, and apical diameters of capillaries seem to be related to Polycythemia vera.

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“…71,79 Structural abnormalities such as devascularization and distortion of architecture, which characterize late microvascular damage, are strong predictors of occurrence of digital ulcers. 80 Available evidence indicates a positive correlation between nail-fold capillaroscopy abnormalities and involvement of target organs. 80…”

Section: Systemic Sclerosis (Grade Of Recommendation -A)mentioning

confidence: 99%

Nail-fold capillaroscopy for the dermatologists

Grover¹,

Jakhar

Mishra³

et al. 2021

IJDVL

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Nail fold is one of the most accessible sites for studying changes in the microcirculation in various microangiopathies. The characterization of changes in microvasculature can provide useful clues towards the diagnosis and prognosis of a disease. The diagnostic utility of nail fold capillaroscopy has improved and expanded over the past couple of decades. Beyond connective tissue diseases, it is now explored for its role in various systemic and dermatological diseases. Incorporation of nail-fold capillaroscopy in the diagnostic criteria of systemic sclerosis has generated interest among dermatologists. The current review is aimed at providing knowledge about nail-fold capillaroscopy to dermatologists. For the purpose of review, a PubMed search was done using the keywords “nail fold capillaries” and “nail fold capillaroscopy”. All the articles were retrieved and classified into reviews and clinical studies of various types. The final data were then analyzed and presented in a narrative fashion.

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Position article and guidelines 2018 recommendations of the Brazilian Society of Rheumatology for the indication, interpretation and performance of nailfold capillaroscopy

Cited by 21 publications

References 96 publications

Effect of skin phototype on quantitative nailfold capillaroscopy

Effect of skin phototype on quantitative nailfold capillaroscopy

Use of nailfold video capillaroscopy in polycythemia vera

Nail-fold capillaroscopy for the dermatologists

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