Fertility preservation in gynecologic cancer patients

Abstract

Fertility preservation in cancer patients is possible through conservative surgery or assisted reproduction techniques.• Patients of childbearing age with a diagnosis of malignancy benefit from reproductive counseling.• Oncological and reproductive information results in lower rates of regret, even when the patient chooses to abandon conservative treatment. • Criteria for indicating conservative treatment in cervical, endometrial and ovarian cancer are presented in this position statement. • Conservative treatment modalities in cervical, endometrial and ovarian cancer are discussed together with the respective oncological and reproductive outcomes. FEBRASGO POSITION STATEMENTFertility preservation in gynecologic cancer patients

Fertility preservation in gynecological cancers: an updated overview

“…Additionally, there should be no parametrial invasion, lymph node metastases, or known infertility. Neuroendocrine and non-HPV-associated adenocarcinoma are not suitable for conservative treatment [8], [9].…”

“…Ultrasound-guided cervical length monitoring, vaginal progesterone and vaginal cerclage, as well as detection of asymptomatic bacteriuria are all suggested. Priority is given to elective cesarean section [9].…”

“…The recommended follow-up term for pregnancy is 6-12 months. After pregnancy, radical treatment is not recommended [8], [9].…”

“…Some studies indicate that lower doses, such as 10 mg/day of MPA and 160 mg/day of MA, may induce improved responses. The duration of treatment can range between eight weeks and nine months [9], [16], [21]. Possible adverse effects include weight gain, thrombosis, mood fluctuations, headache, and tension in the breasts [9].…”

“…The duration of treatment can range between eight weeks and nine months [9], [16], [21]. Possible adverse effects include weight gain, thrombosis, mood fluctuations, headache, and tension in the breasts [9].…”