Oral Iron Supplementation in Pregnancy: Current Recommendations and Evidence-Based Medicine

Duarte, Ana Filipa Moreira; Carneiro, Ana Catarina Simões Viana; Peixoto, Ana; Montenegro, Daniela Filipa Pereira; Campos, Débora Sofia Carvalho; Alves, Ana Patrícia Ribeiro; Costa, Ana Rita Mota Magalhães; Fino, Patrícia

doi:10.1055/s-0041-1736144

Cited by 3 publications

(1 citation statement)

References 12 publications

(12 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Women should be extensively counselled about the need for a varied and balanced diet during pregnancy in order to maximize short and long-term maternal and perinatal outcomes [ 46 , 47 , 48 ]. Furthermore, because pregnancy is not commonly planned, it is also necessary to raise awareness of the importance of a balanced diet and correct lifestyle among women of childbearing age [ 49 ].…”

Section: Discussionmentioning

confidence: 99%

Systematic Review and Critical Evaluation of Quality of Clinical Practice Guidelines on Nutrition in Pregnancy

et al. 2022

View full text Add to dashboard Cite

Objective: To report the quality and clinical heterogeneity of the published clinical practice guidelines (CPGs) on nutrition in pregnancy. Methods: MEDLINE, Embase, Scopus, and ISI Web of Science databases were searched. The following aspects related to nutrition in pregnancy were addressed: specific requirements during pregnancy, description of a balanced diet, weight gain, prevention of food-borne, nutrition in peculiar sub-groups of women, and maternal or perinatal outcomes. The assessment of the risk of bias and quality assessment of the included CPGs were performed using “The Appraisal of Guidelines for REsearch and Evaluation (AGREE II)” tool divided in six quality domains: scope and purpose, stakeholder involvement, rigor of development, clarity of presentation, applicability, editorial independence. Mean ± standard deviation (SD) was used to summarize the scores across all the guidelines per domain. The quality of each guideline was computed using the scoring system proposed by Amer et al. A cut-off of >60% was sued to define a CGP as recommended. Results: Eighteen CPGs were included. There was a substantial heterogeneity in the recommended dose for vitamins, folic acid, and micronutrient intake during pregnancy among the different published CPGs. 27.8% (5/18) of the CPGs recommended a daily intake of folic acid of 200 mcg, 38.8% (7/18) 400 mcg, 16.7% (3/18) 600 mcg while the remaining CPGs suggested dose between 400 and 600–800 mc per day. Adequate maternal hydration was advocated in the large majority of included CPGs, but a specific amount of water intake was not reported in 83.3% (15/18) cases. There was also significant heterogeneity in various other aspects of nutrition recommendation among the different CPGs, including gestational weight gain (55.5%), prevention of food-borne diseases in pregnancy (72.2%), nutrition in particular groups of pregnant women (83.3%), maternal and perinatal outcomes (72.2%). The AGREE II standardized domain scores for the first overall assessment (OA1) had a mean of 65% but only half scored more than 60%. Conclusion: The published CPGs on nutrition in pregnancy show an overall good methodology, but also a substantial heterogeneity as regard as different major aspects on nutrition in pregnancy.

show abstract

Section: Discussionmentioning

confidence: 99%

Systematic Review and Critical Evaluation of Quality of Clinical Practice Guidelines on Nutrition in Pregnancy

et al. 2022

View full text Add to dashboard Cite

show abstract

Iron deficiency and overload in men and woman of reproductive age, and pregnant women

Liu

Duan

Tan

et al. 2023

Reproductive Toxicology

View full text Add to dashboard Cite

Nutritional support during pregnancy

Mozes,

Elgina,

Mozes

et al. 2024

Akušerstvo, ginekologiâ i reprodukciâ

View full text Add to dashboard Cite

Aim: to summarize new data regarding the effectiveness of nutritional support during pregnancy.Materials and Methods. A search for publications was carried out in the PubMed/MEDLINE, Scopus, Web of Science, RSCI databases by retrieving queries for the following keywords: nutritional support, pregnancy, micronutrients, vitamins, macronutrients, without language restrictions. 71 sources with full text access were selected for analysis.Results. Nutritional status during pregnancy markedly impacts on mother's and neonate’s health. During pregnancy, requirements for macro- and micronutrients increase to maintain maternal homeostasis and support fetal growth. Increasing calorie intake in general female population demonstrates modest effects on pregnancy and fetal outcomes, whereas for pregnant women in poor income countries it results in no long-term benefits for children by assessing their anthropometric parameters and neurocognitive development. Despite the lack of conclusive evidence, in many countries sensible calorie restriction during pregnancy is recommended. Some micronutrients are vital for mother and fetus, because their deficiency is accompanied by increased risk of adverse pregnancy outcomes. For instance, folic acid deficiency is associated with the risk of developing fetal neural tube defects, iodine deficiency is coupled to the risk of emerging pediatric intellectual development disorders associated with congenital hypothyroidism, and calcium deficiency is related to a high risk of maternal hypertensive disorders. Therefore, micronutrient supplementation represents a technology with good potential in fighting for maternal and child health. Nonetheless, despite some advances in understanding nutritional support in pregnant women, many studies provide controversial data substantiating a need to conduct further investigations.Conclusion. Overall, recent year research confirms that the supplementation of micro- and macronutrients during pregnancy is an effective tool for “fetal programming” allowing to impact on maternal and fetal health. At the same time, an analysis of the literature showed a significant lack of research in the field of creating individual nutrition programs and nutritional support for pregnant women belonging to different segments of the population, living in different geographical regions, etc.

show abstract

Oral Iron Supplementation in Pregnancy: Current Recommendations and Evidence-Based Medicine

Cited by 3 publications

References 12 publications

Systematic Review and Critical Evaluation of Quality of Clinical Practice Guidelines on Nutrition in Pregnancy

Systematic Review and Critical Evaluation of Quality of Clinical Practice Guidelines on Nutrition in Pregnancy

Iron deficiency and overload in men and woman of reproductive age, and pregnant women

Nutritional support during pregnancy

Contact Info

Product

Resources

About