Reproductive Outcomes in Cases of Subclinical Hypothyroidism and Thyroid Autoimmunity: A Narrative Review

Abstract

Thyroid diseases are relatively common in women in the reproductive period. It is currently understood that clinically-evident thyroid disorders may impair ovulation and, consequently, fertility. However, to date it has not been proven that high serum levels of thyroid-stimulating hormone and/or positivity for antithyroid antibodies are associated to a reduction in fertility, mainly in the absence of altered thyroxine levels. The present comprehensive review aims to present current data on the association between subclinical hypothyroidism and/or thyroid autoimmunity and reproductive outcomes.

Repercussion of thyroid dysfunctions in thyroidology on the reproductive system: Conditio sine qua non?

“…Clinical hypothyroidism and hyperthyroidism necessitate treatment. In addition, it was propounded that the treatment for subclinical hypothyroidism in gestation is useful as it is on the occasion of autoimmune thyroid disease 9,10 . Herewith, hormones…”

“…Clinical hypothyroidism and hyperthyroidism necessitate treatment. In addition, it was propounded that the treatment for subclinical hypothyroidism in gestation is useful as it is on the occasion of autoimmune thyroid disease 9 , 10 . Herewith, hormones of this delicate 11 , 12 , 13 endocrine gland are crucial and vital, sine qua non , in terms of miscellaneous physiological processes of humans and animals.…”