Foreign Body in Jugal Mucosa

Abstract

Introduction Foreign body in the oral cavity may be asymptomatic for long time and only sometimes it can lead to a typical granulomatous foreign body reaction. Some patients may complain of oral pain and present signs of inflammation with purulent discharge. A granuloma is a distinct, compact microscopic structure composed of epithelioid-shaped macrophages typically surrounded by a rim of lymphocytes and filled with fibroblasts and collagen. Nowadays, the increase of cosmetic invasive procedures such as injection of prosthetic materials in lips and cheeks may lead to unusual forms of inflammatory granulomas. Objectives Describe an unusual presentation of a foreign body reaction in the buccal mucosa due to previous injection of cosmetic agent. Resumed Report A 74-year-old woman was referred to the Department of Otorhinolaryngology, Head and Neck Surgery to investigate the presence of multiple painless, bilateral nodules in the buccal mucosa, with progressive growth observed during the previous 2 months. The histologic results showed a foreign body inflammatory reaction. Conclusion Oral granulomatosis lesions represent a challenging diagnosis for clinicians and a biopsy may be necessary. Patients may feel ashamed to report previous aesthetic procedures, and the clinicians must have a proactive approach.

Foreign Body Granuloma in the Tongue by a Pequi Spine

“…The time for the appearance of a foreign body granuloma can vary from a few days to years [ 15 ], and, clinically, it presents as a local inflammatory reaction, associated or not with purulent secretion, pain [ 3 , 5 , 16 ], material migration [ 5 , 16 ], slight swelling, ulcerations [ 4 ], and color changes, which range from grayish black to bright red [ 17 ]. It is rare to find cases in which the foreign body granuloma developed in the oral cavity is asymptomatic [ 3 , 5 , 16 ]. The signs and symptoms found in the case in question confirm what is described in the literature, since the patient had noticeable swelling on the side of the tongue, pain, and difficulty in swallowing.…”

“…True granulomas are compact microscopic structures, formed by the collection of epithelioid histiocytes, surrounded by inflammatory cells and filled with fibroblasts and collagen fibers, in response to the persistence of some stimulus [ 1 – 3 ]. The presence of multinucleated giant cells, formed by the coalescence of macrophages, can also be observed [ 2 ].…”

Foreign body reaction simulating mandibular osteosarcoma—Case report

“…Granulomas show preference for female individuals, probably because women seek cosmetic care more often [7]. Tamiolakis et al [3] reported two cases of foreign body granuloma following the use of soft tissue fillers, presenting a review of the literature about the matter.…”

“…Granulomas are microscopic structures composed of macrophages, surrounded by lymphocytes and filled with collagen fibers and fibroblasts [7]. Although they can occur with all injectable dermal fillers, the incidence is very rare (0.01–1.0%) and usually appears after a latency period, which may be several months to years after the injection [8].…”