Substance use and sexual function in juvenile idiopathic arthritis

Weelden, Marlon van; Lourenço, Benito; Viola, Gabriela R.; Aikawa, Nádia E.; Queiroz, Lígia Bruni; Silva, Clóvis A.

doi:10.1016/j.rbre.2016.02.007

Cited by 7 publications

(13 citation statements)

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“…Su utilización en diferentes países y en distintos contextos ha dado muestras de su enorme potencial (Agley, Gassman, Jun, Nowicke y Samuel, 2015;Bernard et al, 2005;Cote-Menendez et al, 2013;Cummins et al, 2003;Dieppe, Stanhope y Rakhra, 2009;Harris et al, 2016Harris et al, , 2014Karila et al, 2007;Van Weelden et al, 2016). En España, aunque algunos profesionales e investigadores han utilizado ocasionalmente el CRAFFT, todavía no existen estudios psicométricos que garanticen el adecuado funcionamiento de este instrumento en nuestro país.…”

Section: Discussionunclassified

Validación empírica del CRAFFT Abuse Screening Test en una muestra de adolescentes españoles

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Section: Discussionunclassified

Validación empírica del CRAFFT Abuse Screening Test en una muestra de adolescentes españoles

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“…Dr. Eneas Carvalho Aguiar, 647 -Cerqueira César, São Paulo, SP 05403-000, Brazil. 4 Adolescent Unit, Children's Institute, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, São Paulo, SP, Brazil.…”

Section: Acknowledgementsmentioning

confidence: 99%

“…This painful and disable disease occurs mainly in females during the adolescence and young adulthood. Patients may have a precocious sexual activity with a possibility of sexually transmitted infections (STI) [4].…”

Section: Introductionmentioning

confidence: 99%

Lower genital tract infections in young female juvenile idiopathic arthritis patients

et al. 2019

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Background: To evaluate human papillomavirus (HPV), Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) infections in juvenile idiopathic arthritis (JIA) patients. Methods: After exclusion, 33 female adolescent and young JIA patients (ILAR criteria) and 28 healthy controls were selected for this study. Demographic data, gynecological, sexual function, cervical cytology and histological abnormalities were evaluated. JIA clinical/laboratorial parameters and treatment were also assessed. HPV-DNA, CT-DNA and NG-DNA testing in cervical specimens were performed by Hybrid Capture 2 assays. Results: The mean current age was similar in JIA patients and controls (23.3 ± 6.24 vs. 26.1 ± 6.03 years, p = 0.09). The frequencies of sexual intercourse (76% vs. 89%, p = 0.201) and abnormal cervical cytology (24% vs. 11%, p = 0.201) were similar in JIA compared to controls. The higher frequency of HPV infection in JIA patients than controls (30% vs. 11%, p = 0.155) did not reach statistical significance. CT (0% vs. 7%, p = 0.207) and NG infections (0% vs. 4%, p = 0.459) were also alike in both groups. Further evaluation of JIA patients with abnormal and normal cervical cytology showed that the former group had a higher frequency of HPV infection (87% vs. 12%, p = 0.0002) with a low frequency of HPV vaccination (0% vs. 8%, p = 1.0). No differences were evidenced between these two JIA groups regarding demographic data, sexual function and clinical/laboratorial parameters. The frequencies of methotrexate (p = 0.206) and biological agent use (p = 0.238) were similar in both JIA groups. Conclusions: To our knowledge, this was the first study to assess lower genital infections in JIA patients allowing the identification of HPV as main cause of cervical dysplasia. Methotrexate and biological agents do not seem to increase risk of lower genital tract infections in JIA patients.

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“…It is, therefore, time for general pediatrics [3,4] and pediatric specialties [5], including pediatric rheumatic patients, to rethink the age limit in pediatric care. The upper age limit of 21 years for adolescence was first suggested by American Academy of Pediatrics [2,6].…”

Section: Upper Age Limit For Adolescencementioning

confidence: 99%

“…For rheumatic disease patients, there are other challenges that occur in daily clinical practice in late adolescence. These issues may be related to emotional immaturity, delayed financial independence, disease activity, medications, nervous central system cumulative damage, non-adherence to drug treatment and appointments, licit/illicit drugs use, violence (bullying, suicide), risk of sexually transmitted infection, infertility issues, as well as precocious sexuality and pregnancy, reinforcing the need of age cut-off extension [5].…”

Section: Challenges For Rheumatic Disease Patientsmentioning

confidence: 99%

Pediatric rheumatic disease patients: time to extend the age limit of adolescence?

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Adolescence and young adulthood definitions Adolescence (aged 10-19 years) according to World Health Organization is a period involving biological, psychological, sociocultural expressions and cognitive development. During this stage, adolescents become gradually more independent, with parents' autonomy, attachment with the peers, beginning sexual interests and with penal responsibility [1, 2]. Young adulthood (aged 18-26 years) is a lifespan period that generally occurs complete independency, romantic relationships, end of college, begin working, become financially autonomous, leave home and start a family [3].

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Substance use and sexual function in juvenile idiopathic arthritis

Abstract: A high risk for substance abuse/dependence was observed in both JIA and controls. JIA substance users were more likely to have sexual intercourse. Therefore, routine screening is suggested in all visits of JIA adolescents.

Cited by 7 publications

References 11 publications

Validación empírica del CRAFFT Abuse Screening Test en una muestra de adolescentes españoles

Validación empírica del CRAFFT Abuse Screening Test en una muestra de adolescentes españoles

Lower genital tract infections in young female juvenile idiopathic arthritis patients

Pediatric rheumatic disease patients: time to extend the age limit of adolescence?

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